Navigation Links
Initial Steps In Spread Of Cancer Identified

Scientists have now discovered how cancer cells are able to spread to distant parts of the body. It was previously though that these cells spread to the target site via the blood or the lymph// and then started forming a new tumor there.

It has now emerged that certain chemicals secreted by the tumors do the job of preparing the potential "landing" site by altering the conditions to make them ideal for cancer growth. Researchers from the Cornell University's Weill Medical College in New York have published their findings in today's issue of the journal Nature. Their study demonstrates that cancer cells induce certain bone marrow cells to migrate to distant organs and prepare the site for further colonization by the tumor. If these bone marrow cells can be blocked by drugs, then the spread of cancer, which is what makes the disease so deadly can be easily contained, "These nests provide attachment factors for the tumor cells to implant and nurture them. It causes them not only to bind but to proliferate. Once that all takes place we have a fully formed metastatic site or secondary tumor," said Lead researcher Dr David Lyden. He added that for the first time the initial steps involved in metastasis were mapped out. "By blocking bone marrow cells using antibodies, we are capable of preventing tumor cells implanting and thus the spread of cancer," he observed.

The current study shows that the initial protein that is sent out as an emissary is fibronectin. Once it has entrenched into the area, a second growth factor arrives and thus bone marrow cells can easily colonize this area. Once this happens, malignant cells that arrive later have a foundation that can begin the formation of secondary cancer. These steps were shown in mice, whose bone marrow cells were killed by irradiation. The researchers then injected skin cancer and lung cancer cells into these mice after supplying bone marrow cells tagged with green fluorescent protein. This enabled them t o track the progress of the cells in the body. The cancer cells were tagged with red fluorescent protein. The researchers found that green cells appeared in the lungs many days before the actual tumor cells arrived, thus signaling that they were preparing the site for invasion of the cancer cells.


'"/>




Related medicine news :

1. Detecting Lung Cancer In Its Initial Stages
2. New Screening Method Found To Detect Testicular Cancer In Its Initial Stages
3. Initial tests negative for bird flu in Romanian Woman
4. Elastrography, may Call the Shots During Initial Stage of Breast Screening
5. Steps To Improve Quality Of Plant-Based Drugs
6. Few Simple Steps to Lower The Incidence Of SIDS
7. Simple Steps To Help Fight Asthma
8. WHO Steps Up To Create A Public Awareness About The Consequences Of Exposure To Radon
9. Steps Taken To Maintain Inflation Rates Says Chidambaram
10. Government Takes Steps to Reduce Binge Drinking Among Britons
11. Its High Time the Australian Government Takes Steps against Diabetes
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/4/2016)... (PRWEB) , ... May 04, 2016 , ... ... April 2016. SS&A teamed up with one of the top website design companies ... portal contains informative legal articles related to the law firm's main practice areas. ...
(Date:5/4/2016)... ... May 04, 2016 , ... Nordic Naturals ... cellular and metabolic health. This synergistic combination of omega-3 fatty acids and potent ... 150 mg of reduced glutathione and 200 mg of N-Acetylcysteine (NAC). , ...
(Date:5/4/2016)... ... 2016 , ... Natalie Jill is a well respected lifestyle mentor ... the launch of her new book: Natalie Jill’s 7 Day Jump Start: Unprocess Your ... jump start a new healthy lifestyle featuring simple recipes using MitoXcell’s raw cacao formula. ...
(Date:5/4/2016)... ... May 04, 2016 , ... Bayco ... compact tactical (6.7 inch) dual-light flashlights in models NSP-9842XL and NSR-9844XL . ... retail starting at $59.95) uses 2 included CR-123 batteries to produce up to ...
(Date:5/4/2016)... ... May 04, 2016 , ... ... knees, ankles, and elbows. Engineered with athletes in mind, OMNIFORCE offers high-performance, ... to ineffective circular knitting, common in the industry) produces premium flat-knit construction ...
Breaking Medicine News(10 mins):
(Date:5/3/2016)... Research and Markets has announced the addition ... Outlook 2020" report to their offering. ... has improved significantly in past years due to which ... years. Many cancer drugs have been developed by utilization ... expected to be developed with its help. They are ...
(Date:5/3/2016)... may be familiar with watching a film or TV show in high definition, you may ... the Medical Industry.  Ampronix  is a renowned authorized reseller of the medical industry,s top brands ... http://photos.prnewswire.com/prnh/20160502/362730 ... ... ...
(Date:5/3/2016)... , May 3, 2016  Specialty Silicone ... tool that shows how a cleanroom works. The ... discussions about science and technology. ... "As a technology company, SSF enthusiastically supports the ... help educators foster the next generation of innovators. ...
Breaking Medicine Technology: