Navigation Links
Initial Steps In Spread Of Cancer Identified

Scientists have now discovered how cancer cells are able to spread to distant parts of the body. It was previously though that these cells spread to the target site via the blood or the lymph// and then started forming a new tumor there.

It has now emerged that certain chemicals secreted by the tumors do the job of preparing the potential "landing" site by altering the conditions to make them ideal for cancer growth. Researchers from the Cornell University's Weill Medical College in New York have published their findings in today's issue of the journal Nature. Their study demonstrates that cancer cells induce certain bone marrow cells to migrate to distant organs and prepare the site for further colonization by the tumor. If these bone marrow cells can be blocked by drugs, then the spread of cancer, which is what makes the disease so deadly can be easily contained, "These nests provide attachment factors for the tumor cells to implant and nurture them. It causes them not only to bind but to proliferate. Once that all takes place we have a fully formed metastatic site or secondary tumor," said Lead researcher Dr David Lyden. He added that for the first time the initial steps involved in metastasis were mapped out. "By blocking bone marrow cells using antibodies, we are capable of preventing tumor cells implanting and thus the spread of cancer," he observed.

The current study shows that the initial protein that is sent out as an emissary is fibronectin. Once it has entrenched into the area, a second growth factor arrives and thus bone marrow cells can easily colonize this area. Once this happens, malignant cells that arrive later have a foundation that can begin the formation of secondary cancer. These steps were shown in mice, whose bone marrow cells were killed by irradiation. The researchers then injected skin cancer and lung cancer cells into these mice after supplying bone marrow cells tagged with green fluorescent protein. This enabled them t o track the progress of the cells in the body. The cancer cells were tagged with red fluorescent protein. The researchers found that green cells appeared in the lungs many days before the actual tumor cells arrived, thus signaling that they were preparing the site for invasion of the cancer cells.


'"/>




Related medicine news :

1. Detecting Lung Cancer In Its Initial Stages
2. New Screening Method Found To Detect Testicular Cancer In Its Initial Stages
3. Initial tests negative for bird flu in Romanian Woman
4. Elastrography, may Call the Shots During Initial Stage of Breast Screening
5. Steps To Improve Quality Of Plant-Based Drugs
6. Few Simple Steps to Lower The Incidence Of SIDS
7. Simple Steps To Help Fight Asthma
8. WHO Steps Up To Create A Public Awareness About The Consequences Of Exposure To Radon
9. Steps Taken To Maintain Inflation Rates Says Chidambaram
10. Government Takes Steps to Reduce Binge Drinking Among Britons
11. Its High Time the Australian Government Takes Steps against Diabetes
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/5/2016)... (PRWEB) , ... February 05, 2016 , ... Regular gym ... find themselves having to wait longer to access the treadmills. It’s a predictable trend. ... resolutions to lose weight and get in shape by joining gyms, starting new walking ...
(Date:2/5/2016)... ... ... Dr. Justin Scott and Dr. Lydia Muccioli of Pure Dental Health ... in need. The event is scheduled to take place on February 27, 2016 from ... dental care to community members in need. Each patient will be given the opportunity ...
(Date:2/5/2016)... ... February 05, 2016 , ... Health and wellness is a ... individuals in the event they are experiencing an illness. Migraines are a severe form ... are afflicted with migraines would not wish the pain on their worst enemy, the ...
(Date:2/5/2016)... ... 2016 , ... –This week, Atascadero water heater company First Call Plumbing ... To view the report, click here or see below. , There ... pros and cons, the type chosen is almost entirely up to personal preference. However, ...
(Date:2/4/2016)... ... February 04, 2016 , ... American Addiction Centers ... the start of Project HoldSpace. Through the partnership, the two organizations seek to ... youth between the ages of 13 and 18. Currently focused on Ohio schools, ...
Breaking Medicine News(10 mins):
(Date:2/5/2016)... 2016  Patients in Alabama seeking ... therapy no longer have to travel out of state. ... Urology Centers of Alabama to provide a total ... qualifying patients. Alabama is ... of prostate cancer using many different modalities. They are the ...
(Date:2/5/2016)... 2016 --> ... that the global active pharmaceuticals ingredients (APIs) market stood ... reach US$185.9 bn by 2020. It is expected to ... 2020. The title of the report is "Active Pharmaceutical ... and by Therapeutic Area) - Global Industry Analysis, Size, ...
(Date:2/5/2016)... 2016 Site Profile: --> ... - The Speech Recognition People, announced their latest primary healthcare case ... care, reduce turnaround times and to save the practice money. ... since 2013 Challenge: --> ,- Wirral CCG ... - Six doctors ,- Wirral CCG ,- VoicePower client since 2013 ...
Breaking Medicine Technology: