Navigation Links
Inflammatory Bowel Diseases Cured By Parasitic Worms

Parasitic worms scores better to fight against bowel diseases, reported Linda Mansfield, a researcher of Michigan State University. // Her research is sponsored by Food and Waterborne Diseases Integrated Research Network.

Her research is part of a more than $10 million National Institutes of Health grant supporting the Food and Waterborne Diseases Integrated Research Network of laboratories launched by the National Institutes of Allergy and Infectious Diseases.

Some researchers argue that improved hygiene throughout the developed world may be responsible for inflammatory bowel disease, as well as a whole range of autoimmune disorders. According to this ‘hygiene hypothesis,’ immune systems require exposure to infections of all sorts early in life in order to develop sufficiently.

Intriguingly, inflammatory bowel disease, which has two forms – Crohn's disease and ulcerative colitis – is virtually unknown in the developing world, while it is increasing dramatically in developed societies. When people from developing countries move to developed ones, their incidence of the disease tends to increase.

‘We know from veterinary medicine that many bacterial and protozoan pathogens, especially those that multiply inside of cells, elicit an immune response in the host that would normally cause inflammation, but that worm parasites mount an anti-inflammatory defense that modulates it,’ said Mansfield, a professor of large animal clinical sciences. ‘The greater the immune response, the greater the anti-inflammatory effect.

‘It's possible that the human immune system developed in a way that is dependent on parasitic worms to regulate immune responses.’

The particular worm that Mansfield and colleagues are studying as a potential treatment is known as the whipworm, or Trichuris suis, which is a parasite that afflicts pigs. Early studies have shown that giving humans a concoction of whipworm eggs and Gatorade is very e ffective in treating inflammatory bowel disease.

Mansfield and colleagues are using some of the NIH funding to develop an animal model to test the effectiveness of the worms on inflammatory bowel disease and other maladies. Also, she is waiting for word on a new NIH grant that will support efforts to learn how the treatment works.

‘The bottom line right now is that we know none of the mechanisms of how this works,’ she said.

Mansfield, as well as other researchers, also wants to apply this effort to a variety of autoimmune conditions, such as asthma, diabetes and multiple sclerosis. Some researchers suggest that all of these conditions can be explained as combinations of the hygiene hypothesis and genetics.

Source: Erekalert
'"/>




Related medicine news :

1. The Usage Of Anti-Inflammatory Drugs Questioned
2. Hope For Patients With Inflammatory Bowel Disease
3. FDA to bring about changes in Marketed Non-Steroidal Anti-Inflammatory Drugs
4. Inflammatory bowel disease linked to genetic abnormality
5. Elevated Insulin Levels To Influence Levels Of Inflammatory Markers
6. Cannabinoids - Antidepressant And Inflammatory Bowel Disease Treatment
7. Ambiguous Efficacy Of Opioid Drugs In Chronic Inflammatory Joint Pain Relief
8. A Component In Milk May Help Control Inflammatory Diseases
9. Five New Anti-Inflammatory Compounds Produced By Indian Scientists
10. Australian Scientists Develop Novel Drug To Combat Inflammatory Diseases
11. Spanish Initiative Looks At Inflammatory Markers To Predict Strokes
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/26/2016)... ... June 26, 2016 , ... PawPaws brand pet supplements owned by ... to enhance the health of felines. The formula is all-natural and is made from ... the PawPaws Cat Kidney Support Supplement Soft Chews are Astragalus Root Extract ...
(Date:6/25/2016)... ... ... temporary closing of Bruton Memorial Library on June 21 due to a possible lice infestation, ... aspect of head lice: the parasite’s ability to live away from a human host, and ... necessary one in the event that lice have simply gotten out of control. , As ...
(Date:6/25/2016)... ... ... Friday, June 10, Van Mitchell, Secretary of the Maryland Department of Health and Mental ... exemplary accomplishments in worksite health promotion. , The Wellness at Work Awards took place ... BWI Marriott in Linthicum Heights. iHire was one of 42 businesses to receive an ...
(Date:6/24/2016)... CA (PRWEB) , ... June 24, 2016 , ... Marcy was in a crisis. Her ... would lash out at his family verbally and physically. , “When something upset him, he ... he would use it. He would throw rocks at my other children and say he ...
(Date:6/24/2016)... ... June 24, 2016 , ... Topical BioMedics, Inc, makers of Topricin and MyPainAway Pain Relief ... a minimum wage raise to $12 an hour by 2020 and then adjusting it yearly ... lost value of the minimum wage, assure the wage floor does not erode again, and ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... HILLS, Calif. , June 23, 2016 Any ... the many challenges of the current process. Many of them ... because of the technical difficulties and high laboratory costs involved. ... have to offer it at such a high cost that ... afford it. Dr. Parsa Zadeh , founder ...
(Date:6/23/2016)... INDIANAPOLIS , June 23, 2016 Roche ... received 510(k) clearance for its Elecsys BRAHMS PCT (procalcitonin) ... severe sepsis or septic shock. With this clearance, Roche ... provide a fully integrated solution for sepsis risk assessment ... associated with bacterial infection and PCT levels in blood ...
(Date:6/23/2016)... 23, 2016 Research and Markets has ... 52" report to their offering. ... creates a favourable commercial environment for MedImmune to enter. The ... that will serve to drive considerable growth for effective anti-influenza ... to cap sales considerably, but development is still in its ...
Breaking Medicine Technology: