Navigation Links
Inflammation Promotes Metastasis of Prostate Cancer

A new research strongly suggests that inflammation associated with the progression of tumors actually plays a key role in the metastasis of prostate cancer.//

According to this research conducted at the University of California, San Diego (UCSD) School of Medicine "mounting an immune response" or "having your body fight the cancer" may not be a good thing.

The research, appearing online March 19 in advance of publication in the journal Nature, was conducted by Michael Karin, Ph.D., and colleagues, identifies a mechanism which triggers metastasis, which is the spread of cancer in late stages of prostate cancer development.

Furthermore, this new work may lead to development of anti-metastatic therapies.

A major hypothesis in cancer research has been that whether the cancer metastisizes or not is determined by genetic changes within the cancer cell itself. But this hypothesis didn't explain why metastases appear many years after the initial tumor.

"Our findings suggest that promoting inflammation of the cancerous tissue, for instance, by performing prostate biopsies, may, ironically, hasten progression of metastasis," said Karin. "We have shown that proteins produced by inflammatory cells are the 'smoking gun' behind prostate cancer metastasis. The next step is to completely indict one of them."

One in six men will be diagnosed with prostate cancer, and one in 33 will die of metastatic disease. Early tumors confined to the prostate can be treated, but no effective treatments are available for metastatic disease, according to Steven L. Gonias, M.D., Ph.D., professor and chair of the UCSD Department of Pathology, a study investigator.

"This study helps explain the paradox that, in certain types of malignancy, inflammation within a cancer may be counterproductive," said Gonias.

In research using mouse models and confirmed in human tissue, the scientists observed that a protein kinase cal
'"/>




Page: 1 2 3

Related medicine news :

1. Inflammation may help battle infection in gums
2. Inflammation Linked to Colon Cancer
3. Bee Venom Effective In Reducing Inflammation
4. Inflammation reduced by consuming oily fish
5. Research Shows Carbon Monoxide Prevents Inflammations
6. ‘Inflammation Gene’ identified by scientit
7. High-Fat Diet Can Ward Off Inflammation In The Gut
8. Inflammation May Indicate Heart Problems
9. Inflammation and WBC count has a link to deaths by cancer
10. Mediterranean Diet Lowers Inflammation Levels In Elderly
11. PET Scans Help In Monitoring Progress of Lung Inflammation
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Inflammation Promotes Metastasis Prostate Cancer

(Date:2/26/2015)... PartnerTech Inc . has announced it has been named ... , The Movers & Makers Awards are presented in ... distribution of tangible products and will be held on March ... as Georgia’s largest local awards ceremony for manufacturing and supply ... local industry and business leaders. , “We are thrilled ...
(Date:2/26/2015)... (PRWEB) February 26, 2015 Participants ... Initiatives: What’s Working? What’s Not? What’s New? ,” ... dual-eligibles programs to achieve strong outcomes for duals-plan ... been happening in the implementation phase of programs ... been made? Which ones need to be implemented ...
(Date:2/26/2015)... The hip resurfacing procedure at Texas Orthopedics ... John Short to resume his active lifestyle, it has improved ... Mt. Kilimanjaro, the highest free-standing mountain in the world, in ... his late 20s, Short suffered from early onset degeneration. His ... were bone on bone. , Then about five years ...
(Date:2/26/2015)... February 26, 2015 Kantar Health ... The Sunday Times “100 Best Small Companies to Work For” ... UK has been included on the list, which measures employees’ ... fantastic team here at Kantar Health UK, and we are ... Kantar Health UK CFO Mark Hinton-Jones said. “The team is ...
(Date:2/26/2015)... Today, Highmark Health announced that longtime ... stepping down as chairman of the board of directors ... vice chairman of The PNC Financial Services Group, Inc. ... Highmark Health President and Chief Executive Officer David L. ... directors of Highmark Inc.; both changes are effective as ...
Breaking Medicine News(10 mins):Health News:PartnerTech Named a Finalist for Gwinnett County Chamber of Commerce 2015 Movers & Makers Award 2Health News:PartnerTech Named a Finalist for Gwinnett County Chamber of Commerce 2015 Movers & Makers Award 3Health News:Upcoming AIS Virtual Conference Will Explain What Is and Is Not Working in Medicare-Medicaid Dual Eligibles Programs 2Health News:Hip Resurfacing at Texas Orthopedics Enables Patient to Climb Mt. Kilimanjaro 2Health News:Hip Resurfacing at Texas Orthopedics Enables Patient to Climb Mt. Kilimanjaro 3Health News:Kantar Health UK Named One of The Sunday Times 100 Best Small Companies to Work For 2Health News:Highmark Health Appoints Joseph C. Guyaux Chairman of the Board of Directors 2Health News:Highmark Health Appoints Joseph C. Guyaux Chairman of the Board of Directors 3Health News:Highmark Health Appoints Joseph C. Guyaux Chairman of the Board of Directors 4
... Jan. 12 David M. Klein, Ph.D., original co-owner ... Arizona and a developer of that national brand, has ... centers to Arizona.Natural Weight(TM) For Optimized Living is a ... that enables you to become healthier at any weight, ...
... FRANCISCO, Jan. 12 Within health care, dermatology,professionals play ... , The Dermatology Nurses, Association ... practice in a variety,of learning formats and the opportunity ... annual conference slated for March,4-7 at the Hilton San ...
... Also Appoints Industry Veteran Steve Shulman to BoardHOUSTON, ... first and largest provider of outsourced medical implantable ... announced today that its board of directors has ... The company announced the appointment following its second ...
... providing high-quality speech pathology services, according to University ... , Completed through UQ,s School of Health and ... language disorders could be validly and reliably assessed ... , "Having worked clinically with people living with ...
... 12 A partnership between Command Spanish(R), Inc. and ... providers of nursing education, makes the two companies co-providers ... instruction being provided by the two companies allows nurses ... occupational Spanish. Two new courses are available online to ...
... Inc. (Nasdaq: ALXN ), today announced that ... fourth quarter and full year ended December 31, 2008 ... open. Following the release of the financials, Alexion management ... on Thursday, February 12, 2009, at 10:00 a.m. Eastern ...
Cached Medicine News:Health News:Dr. David M. Klein, Innovator of Smart for Life in Arizona, Brings New Weight Management and Wellness Concept to Arizona 2Health News:Dr. David M. Klein, Innovator of Smart for Life in Arizona, Brings New Weight Management and Wellness Concept to Arizona 3Health News:Hop the Trolley for DNA's 27th Annual Conference 2Health News:Access MediQuip Appoints Former Priority Healthcare CEO to Chairman of the Board 2Health News:Access MediQuip Appoints Former Priority Healthcare CEO to Chairman of the Board 3Health News:UQ research finds speech disorders can be assessed from a distance 2Health News:Nurses: Command Spanish Online's Occupational Spanish Language Course Accepted for Credit by the American Nurses Credentialing Center (ANCC) 2
(Date:2/26/2015)... Mass. , Feb. 26, 2015  Spring ... novel therapeutics for the treatment of Hepatitis B ... the closing of a $22 million financing. Funds ... SB 9200, a novel, broad spectrum antiviral agent ... nucleic acid hybrid (SMNH) chemistry platform, into Phase ...
(Date:2/26/2015)... ASHKELON, Israel , Feb. 26, 2015 ... developer of the GlucoTrack ® model DF-F, a ... Dr. Lutz Heinemann , Ph.D., will head its ... key opinion leaders in the field of Diabetes research, ... Heinemann , Ph.D has been Chief Executive Officer and ...
(Date:2/26/2015)... TEL-AVIV, Israel , February 26, 2015 /PRNewswire/ ... company developing a novel cardiac monitoring system for ... today that it has closed a $5 million ... RadBioMed incubator, which is owned jointly by Yehuda ... private investors, including Zohar Gilon, Gur Muntzer and ...
Breaking Medicine Technology:Spring Bank Pharmaceuticals Completes $22 Million Financing 2Integrity Applications Names Prof. Lutz Heinemann to Advisory Board 2Integrity Applications Names Prof. Lutz Heinemann to Advisory Board 3Integrity Applications Names Prof. Lutz Heinemann to Advisory Board 4Vectorious Medical Technologies Completes $5M Raise 2
... Heart IT, the global leader that pioneered the ... WebPAX®, announced today the award of its sixth ... technologies allow health care professionals to view medical ... Internet web browser. This includes Microsoft,s ...
... May 1, 2012  ProUroCare Medical Inc. (OCTBB: PUMD), ... it has received clearance from the U.S. Food ... mechanical imaging (PMI) system.  The approval paves the ... high-resolution visual documentations as an aid in detecting ...
Cached Medicine Technology:U.S. Patent Office Issues Sixth Patent Covering 'Zero-Footprint' Medical Image Viewers to Heart Imaging Technologies, LLC 2ProUroCare Medical Receives FDA Clearance for ProUroScan Elasticity Imaging System 2ProUroCare Medical Receives FDA Clearance for ProUroScan Elasticity Imaging System 3