Navigation Links
Inflammation Linked to Colon Cancer

Inflammation may play a significant role in the development of colon cancer, find researchers publishing in an early online edition of the Proceedings of the National Academy of Sciences. //

Research has shown a role for inflammation in many types of cancer. Most of these studies link the condition to oxidative stress, which in turn causes mutations in specific genes. In this study, investigators from Vanderbilt Institute of Chemical Biology built on this previous work with a study aimed at determining whether the genetic damage resulting from chronic inflammation, called oxidative stress, is limited to the specific cells that are damaged, or whether it invades the cell's DNA as well and thus is passed on to new cells.

Study author Lawrence J. Mamett, Ph.D., explains, "When the body experiences oxidative stress, molecules called free radicals are produced, and these free radicals can damage cells -- the cell membrane and the DNA."

The laboratory study involved a type of DNA damage caused by a product of the COX-2 enzyme, which is known to play a role in inflammation and is blocked by aspirin and other drugs known as COX-2 inhibitors. Researchers took the damaged DNA molecule and inserted it into mammalian kidney cells to see if it would replicate, and it did. The mutations seen in the study are similar to those known to cause an inherited form of colon cancer.

The investigators conclude chronic inflammation causes genetic abnormalities that might lead to cancer.
'"/>




Page: 1

Related medicine news :

1. Inflammation may help battle infection in gums
2. Bee Venom Effective In Reducing Inflammation
3. Inflammation reduced by consuming oily fish
4. Research Shows Carbon Monoxide Prevents Inflammations
5. ‘Inflammation Gene’ identified by scientit
6. High-Fat Diet Can Ward Off Inflammation In The Gut
7. Inflammation May Indicate Heart Problems
8. Inflammation and WBC count has a link to deaths by cancer
9. Mediterranean Diet Lowers Inflammation Levels In Elderly
10. PET Scans Help In Monitoring Progress of Lung Inflammation
11. Single Sugar Enables Antibody to Treat Inflammation
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Inflammation Linked Colon Cancer

(Date:7/11/2014)... Recently, MagicQuinceaneraDresses.com, the popular online supplier ... of 2014 Quinceanera dresses . The company’s new ... look fashionable without paying a large amount of money. ... 57% off. , The company’s online shop has become ... special occasion outfits. In addition to exquisite Quinceanera dresses, ...
(Date:7/11/2014)... The American Association of Poison Control Centers ... commending Senator Bill Nelson (D-FL) for his introduction of ... July 10, 2014. Along with fellow Senate co-sponsors, this ... to enact rules requiring safer, child-resistant packaging for any ... co-sponsors of the bill include: Sen. Richard Blumenthal (D-CT), ...
(Date:7/11/2014)... Down reports that tickets to the Argentina vs. Germany ... between Brazil and Netherlands are in high demand. ... 12th at Estadio Nacional de Brasilia Mane Garrincha Brasila, Federal ... July 13th at Estadio Jornalista Mario Filho - Estadio do ... Cup are guaranteed to be authentic and are covered by ...
(Date:7/11/2014)... 11, 2014 Butler Mobility has recently updated ... Platform Lifts . Previously the two standard colors were ... beautiful earth tone colors as standard colors at no additional ... the home but will enhance the beauty of the stairway. ... home color scheme or individual décor. , The new selection ...
(Date:7/11/2014)... (HealthDay News) -- People with the lowest incomes may have ... disease (PAD), a new study suggests. People with PAD ... limbs, most often the legs. The condition causes leg pain ... throughout the body. People with PAD have a higher risk ... nearly 6,800 people with PAD who took part in the ...
Breaking Medicine News(10 mins):Health News:Cheap Quinceanera Dresses Now Available At MagicQuinceaneraDresses.com 2Health News:AAPCC Issues Statement on the Introduction of the Child Nicotine Poison Prevention Act of 2014 2Health News:AAPCC Issues Statement on the Introduction of the Child Nicotine Poison Prevention Act of 2014 3Health News:Argentina vs. Germany World Cup Finals Tickets & Brazil vs. Netherlands 3rd Place World Cup Tickets Are in Huge Demand 2Health News:Butler Mobility Products Announces Five New Standard Colors for Their Inclined Platform Lifts 2Health News:Poor More Prone to Leg Circulation Trouble 2
... HealthDay Reporter , THURSDAY, Feb. 24 (HealthDay News) -- A ... of the organ a day after birth, scientists report. ... that ways can be found to help the human heart ... heart for regeneration, but they,re somehow permanently switched off," said ...
... New findings by a University of Maryland-led team of ... for a human anti-malarial antibody or a scorpion ... environmentally friendly tool for combating malaria, at a time ... is declining. In a study published in the ...
... By Steven Reinberg HealthDay Reporter , THURSDAY, Feb. ... decades ago, they are still pervasive in the United States ... a new study suggests. In fact, PCBs may account ... after IVF, the researchers said. "These findings may help ...
... redesign of the nation,s donor-liver distribution network developed by ... more people each year receiving the transplants they need. ... Management Science that donor livers currently are doled ... regard for geography and demographics, an arrangement that prevents ...
... State University has secured a $7.9 million award ... through increasing the African nation,s agricultural productivity, creating ... grant, funded by the U.S. Agency for International ... of Florida. The initiative employs trilateral cooperation, which ...
... California A new research study from Loma Linda ... may help contribute to heart health and disease prevention; ... of The Journal of Nutrition . ... as tocopherols, plus numerous phenolic substances, many of them ...
Cached Medicine News:Health News:Scientists Say Newborn Mice Can Regrow Damaged Hearts 2Health News:New study shows ability of transgenic fungi to combat malaria and other bug-borne diseases 2Health News:New study shows ability of transgenic fungi to combat malaria and other bug-borne diseases 3Health News:New study shows ability of transgenic fungi to combat malaria and other bug-borne diseases 4Health News:PCBs Might Be Linked to Failed IVF Attempts 2Health News:Redesign of US donor-liver network could boost transplants by several hundred per year 2Health News:Redesign of US donor-liver network could boost transplants by several hundred per year 3Health News:$7.9 million grant to improve food security, nutrition in Mozambique 2Health News:Antioxidants in pecans may contribute to heart health and disease prevention 2
(Date:1/15/2014)... -- ChinaMarketResearchReports.com adds "China Orthopedic Instrument Industry Report, 2013-2015" ... (Photo: http://photos.prnewswire.com/prnh/20140115/MN46792 ) Benefiting from aging ... China,s orthopedic instrument industry has seen rapid ... from 3.28 billion yuan in 2006 to 9.85 billion ...
(Date:1/15/2014)... Jan. 15, 2014 As health officials across the Midwest ... Meijer pharmacies in Michigan will offer ... patients, enabling Meijer pharmacists to administer tests and, in some ... a physician participating in the study. The ...
(Date:1/15/2014)... Corporation (the "Company") (NASDAQ: CLSN ) today ... to purchase an aggregate of approximately $15 million of ... offering, led by a dedicated health care fund. ... these investors pursuant to which the Company agreed to ...
Breaking Medicine Technology:Orthopedic Instrument Industry in China Markets Forecast to 2015 2Orthopedic Instrument Industry in China Markets Forecast to 2015 3Meijer Pharmacy Offers Free Flu, Strep Testing as Influenza Cases Rise Across the Midwest 2Meijer Pharmacy Offers Free Flu, Strep Testing as Influenza Cases Rise Across the Midwest 3Celsion Corporation Announces $15 Million At-The-Market Registered Direct Offering 2Celsion Corporation Announces $15 Million At-The-Market Registered Direct Offering 3
... 2011 Omeros Corporation (NASDAQ: OMER ) ... in the Company,s Phase 3 clinical program evaluating OMS302 ... proprietary PharmacoSurgery™ products, is added to standard irrigation solution ... maintain intraoperative mydriasis (pupil dilation) and reduce postoperative pain ...
... YORK, Oct. 11, 2011 Reportlinker.com announces ... available in its catalogue: ... 2016 http://www.reportlinker.com/p0336530/Asia-Pacific-Orthopedic-Devices-Market-Outlook-to-2016.html?utm_source=prnewswire&utm_medium=pr&utm_campaign=Orthopedic ... Outlook to 2016 Summary ...
Cached Medicine Technology:Omeros Announces First Patients Treated in Phase 3 Clinical Program Evaluating OMS302 2Omeros Announces First Patients Treated in Phase 3 Clinical Program Evaluating OMS302 3Asia-Pacific Orthopedic Devices Market Outlook to 2016 2Asia-Pacific Orthopedic Devices Market Outlook to 2016 3Asia-Pacific Orthopedic Devices Market Outlook to 2016 4Asia-Pacific Orthopedic Devices Market Outlook to 2016 5Asia-Pacific Orthopedic Devices Market Outlook to 2016 6Asia-Pacific Orthopedic Devices Market Outlook to 2016 7Asia-Pacific Orthopedic Devices Market Outlook to 2016 8Asia-Pacific Orthopedic Devices Market Outlook to 2016 9Asia-Pacific Orthopedic Devices Market Outlook to 2016 10Asia-Pacific Orthopedic Devices Market Outlook to 2016 11Asia-Pacific Orthopedic Devices Market Outlook to 2016 12Asia-Pacific Orthopedic Devices Market Outlook to 2016 13Asia-Pacific Orthopedic Devices Market Outlook to 2016 14Asia-Pacific Orthopedic Devices Market Outlook to 2016 15Asia-Pacific Orthopedic Devices Market Outlook to 2016 16Asia-Pacific Orthopedic Devices Market Outlook to 2016 17Asia-Pacific Orthopedic Devices Market Outlook to 2016 18Asia-Pacific Orthopedic Devices Market Outlook to 2016 19
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: