Navigation Links
Inflammation Linked to Colon Cancer

Inflammation may play a significant role in the development of colon cancer, find researchers publishing in an early online edition of the Proceedings of the National Academy of Sciences. //

Research has shown a role for inflammation in many types of cancer. Most of these studies link the condition to oxidative stress, which in turn causes mutations in specific genes. In this study, investigators from Vanderbilt Institute of Chemical Biology built on this previous work with a study aimed at determining whether the genetic damage resulting from chronic inflammation, called oxidative stress, is limited to the specific cells that are damaged, or whether it invades the cell's DNA as well and thus is passed on to new cells.

Study author Lawrence J. Mamett, Ph.D., explains, "When the body experiences oxidative stress, molecules called free radicals are produced, and these free radicals can damage cells -- the cell membrane and the DNA."

The laboratory study involved a type of DNA damage caused by a product of the COX-2 enzyme, which is known to play a role in inflammation and is blocked by aspirin and other drugs known as COX-2 inhibitors. Researchers took the damaged DNA molecule and inserted it into mammalian kidney cells to see if it would replicate, and it did. The mutations seen in the study are similar to those known to cause an inherited form of colon cancer.

The investigators conclude chronic inflammation causes genetic abnormalities that might lead to cancer.
'"/>




Page: 1

Related medicine news :

1. Inflammation may help battle infection in gums
2. Bee Venom Effective In Reducing Inflammation
3. Inflammation reduced by consuming oily fish
4. Research Shows Carbon Monoxide Prevents Inflammations
5. ‘Inflammation Gene’ identified by scientit
6. High-Fat Diet Can Ward Off Inflammation In The Gut
7. Inflammation May Indicate Heart Problems
8. Inflammation and WBC count has a link to deaths by cancer
9. Mediterranean Diet Lowers Inflammation Levels In Elderly
10. PET Scans Help In Monitoring Progress of Lung Inflammation
11. Single Sugar Enables Antibody to Treat Inflammation
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/2/2016)... , ... May 02, 2016 , ... Eating Recovery ... for eating, mood and anxiety disorders, has rebranded its eating disorder program under a ... residential eating disorder treatment facility on May 16. , To celebrate, ERC Chicago ...
(Date:5/2/2016)... ... 2016 , ... In honor of National Physical Fitness and Sports Month in ... their fitness journey on social media. , The foot care company, which specializes ... product voucher each week during May to one winner. , “Whether the goal is ...
(Date:5/2/2016)... CA (PRWEB) , ... May 02, 2016 , ... Dr. ... provide his patients with same day treatments. In the past, many necessary dental treatments ... or work, along with multiple anesthetic shots and extra chair time. Not only could ...
(Date:5/2/2016)... (PRWEB) , ... May 02, 2016 , ... MedPro Waste ... mail back service. MedPro now offers its mail back service for an all-inclusive ... we are now able to provide service to all of the clients in the ...
(Date:5/2/2016)... NV (PRWEB) , ... May 02, 2016 , ... ... Pharmacy Times, has announced a new Specialty Pharmacy Patient Satisfaction Award that will ... based on the quarterly results from Zitter Health Insights’ Specialty Pharmacy Patient Satisfaction ...
Breaking Medicine News(10 mins):
(Date:4/29/2016)... April 29, 2016 Acquisition ... Sciences, Product Development Capabilities in North ... Base . Indegene ( http://www.indegene.com ... the acquisition of Skura Corporation,s life science business. ... adaptive sales enablement technology for life science organizations ...
(Date:4/28/2016)... 2016  While Abbott,s announced purchase of St. ... repair and stent business, healthcare research firm Kalorama ... firmly into patient monitoring.  Kalorama said that patient ... areas, with double-digit growth expected the next 5 ... Remote Patient Monitoring . Abbott Laboratories agreed ...
(Date:4/28/2016)... , April 28, 2016 ... insights on healthcare, announced today that it has been ... Cool Vendor in Life Sciences, 2016, ... 2016.  The report focuses on life-science- oriented analytics, algorithms ... from patients and doctors, confirm medication ingestion, and analyze ...
Breaking Medicine Technology: