Navigation Links
Inflammation Linked to Colon Cancer

Inflammation may play a significant role in the development of colon cancer, find researchers publishing in an early online edition of the Proceedings of the National Academy of Sciences. //

Research has shown a role for inflammation in many types of cancer. Most of these studies link the condition to oxidative stress, which in turn causes mutations in specific genes. In this study, investigators from Vanderbilt Institute of Chemical Biology built on this previous work with a study aimed at determining whether the genetic damage resulting from chronic inflammation, called oxidative stress, is limited to the specific cells that are damaged, or whether it invades the cell's DNA as well and thus is passed on to new cells.

Study author Lawrence J. Mamett, Ph.D., explains, "When the body experiences oxidative stress, molecules called free radicals are produced, and these free radicals can damage cells -- the cell membrane and the DNA."

The laboratory study involved a type of DNA damage caused by a product of the COX-2 enzyme, which is known to play a role in inflammation and is blocked by aspirin and other drugs known as COX-2 inhibitors. Researchers took the damaged DNA molecule and inserted it into mammalian kidney cells to see if it would replicate, and it did. The mutations seen in the study are similar to those known to cause an inherited form of colon cancer.

The investigators conclude chronic inflammation causes genetic abnormalities that might lead to cancer.
'"/>




Page: 1

Related medicine news :

1. Inflammation may help battle infection in gums
2. Bee Venom Effective In Reducing Inflammation
3. Inflammation reduced by consuming oily fish
4. Research Shows Carbon Monoxide Prevents Inflammations
5. ‘Inflammation Gene’ identified by scientit
6. High-Fat Diet Can Ward Off Inflammation In The Gut
7. Inflammation May Indicate Heart Problems
8. Inflammation and WBC count has a link to deaths by cancer
9. Mediterranean Diet Lowers Inflammation Levels In Elderly
10. PET Scans Help In Monitoring Progress of Lung Inflammation
11. Single Sugar Enables Antibody to Treat Inflammation
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/24/2016)... (PRWEB) , ... May 24, 2016 , ... ... for physical disease or injury that focuses on repairing the musculoskeletal and neuromuscular ... With an emphasis on functional restoration, NYDNRehab began providing treatments for physical therapy ...
(Date:5/24/2016)... ... May 24, 2016 , ... Backed by decades of experience, ... job, ensuring the best suited solution to meet regulatory requirements. Their professional staff ... lab in Istanbul. , Metroloji Okulu specializes in MadgeTech’s line of medical and ...
(Date:5/24/2016)... (PRWEB) , ... May 24, 2016 , ... ... egg freezing, today announced the official relaunch of its community and education hub ... frozen eggs. Eggsurance's mission is to create a safe and welcoming place for ...
(Date:5/24/2016)... ... May 24, 2016 , ... The Radiosurgery Society ... of radiosurgery, is recognizing five medical residents and students for their outstanding contributions ... (SBRT). The awards will be presented at the 2016 SRS/SBRT Scientific Meeting taking ...
(Date:5/24/2016)... ... May 24, 2016 , ... The ... 9.3 million people, or 10% over last year, according to data in the ... group policies was comparatively stable, with a slight decrease in risk-based groups and ...
Breaking Medicine News(10 mins):
(Date:5/23/2016)... -- Experts from various countries ... role of technology in innovative healthcare ... International Conference of VPS-Penn Medicine opened in Abu ... Sheikh Nahyan bin Mubarak Al Nahyan, Minister of Culture and ... provide personalized medicine and tailor-made healthcare in disease treatment and ...
(Date:5/22/2016)... 2016 DS Biopharma (DS) ... anti-inflammatory compound DS102 in chronic obstructive pulmonary disease ... (NASH) patients. Recent DS preclinical data ... tissue and has bronchodilatory, anti-inflammatory and anti-fibrotic properties ... Company will publish further detail on these findings ...
(Date:5/20/2016)... , May 20, 2016 According ... driver is the increasing demand for affordable healthcare solutions as ... steadily on the rise. In countries like the US, the ... In the US, the consumer price index inflation rate stood ... inflation rate moved up to 3.62% during the same time ...
Breaking Medicine Technology: