Navigation Links
Infections Of The Oral Cavity Can Be Treated By Photodynamic Therapy

Anti-biotic resistant bacterial and fungal infections of the oral cavity can be effectively treated by using photodynamic therapy (PDT)//, argue researchers from the University at Buffalo's School of Dental Medicine.

Photodynamic therapy is commonly employed in cancer treatment. PDT is currently employed in the treatment of Kaposi's sarcoma, breast cancer (spread to the chest wall) and cancer of the esophagus.

The treatment modality involves administration of a suitable drug (photosensitizer) followed by exposure to light of a specific wavelength, to kill the cancer cells in a specific way. Active research is being conducted to expand the potential of photodynamic therapy in the treatment of diseases other than cancer.

Following approval of the drug Photofrin? by the FDA, patients with esophageal and endobronchial cancers, peptic ulcer of the lower end of the esophagus (Barrett's esophagus) have had a new ray of hope regarding their treatment.

The researchers of the present study found that minimal doses of PDT delivered to organisms such as S. mutans (a bacteria) and fungal organisms belonging to the genus Candida (obtained from HIV/AIDS patients) resulted in enhanced killing, both in culture plates and biofilms grown on denture material.

In the present study, the FDA approved drug was added to the biofilms and the cultured samples, followed by which the treated samples were exposed to varying degrees of light (light of a specific wavelength, but of different intensities). In less than 15 minutes, PDT was found to destroy nearly 99.9% of the S. mutans bacteria. Significant killing activity could also be demonstrated against C. albicans (thrush), C. glabrata and C. krusei, derived from HIV patients.

Infections with these microorganisms are difficult to treat using conventional antibiotics. In most of the cases, it leads to the development of anti-biotic resistance. PDT, if found to be effective and safe, can overcome both these problems and pave way for the emergence of a new treatment modality. The results of this promising study were presented at the International Association of Dental Research meeting, held at Orlando, Fla.

'The results of the studies so far, while not completed, may have important implications in the treatment of oral infectious diseases currently confounding the medical and dental community. PDT may provide an adjunct to current antibiotic treatment or an alternative where antibiotics no longer are working. This may be vital for patients undergoing cancer therapy, HIV patients who demonstrate resistance to antibiotics and the elderly with persistent oral infections,' concluded Dr. Thomas S. Mang, the study author.


'"/>




Related medicine news :

1. Supplements for Ear Infections
2. Once-Daily Cipro(R) XR for Treating Complicated Urinary Tract Infections
3. Link Between Ear Infections And Asthma
4. Reducing The Rate Of Infections
5. Good News For Individuals Suffering From Frequent Throat Infections
6. Reducing The Rate Of Hospital Acquired Infections
7. Common Infections Found To Raise An Individuals Risk Of Having A Heart Attack Or Stroke
8. Risk Of Developing Infections High In Patients Who Suffer From Abdominal Trauma
9. Fungal Infections Effectively Controlled By Light Therapy
10. Infections in childhood may lead to adult heart disease
11. Understanding Chronic Infections May Help in Developing Therapeutic Vaccines
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/31/2016)... MN (PRWEB) , ... May 31, 2016 , ... DDL, ... the American Association for Laboratory Accreditation (A2LA) to include ISO 594-1 and ISO 594-2 ... common means of achieving a leak-free connection between two medical devices (e.g. a syringe ...
(Date:5/31/2016)... ... May 31, 2016 , ... Like jewels in a crown, the multiple awards ... is home to Ontario’s leading day spa and one of Canada’s few accredited 5 ... a unique concept to combine spa services with hair and beauty services ...
(Date:5/31/2016)... ... May 31, 2016 , ... The Orthopaedic Research and Education Foundation (OREF) ... David G. Lewallen, MD, began his term as president in March, succeeding John J. ... is OREF’s new president-elect. Richard F. Kyle, MD, will serve as chair, corporate development, ...
(Date:5/31/2016)... ... May 31, 2016 , ... ... 2016 Cool Vendors in Security Infrastructure Protection report by Gartner1 Inc. , Each ... series of research reports evaluating these innovative vendors and their products and services. ...
(Date:5/31/2016)... , ... May 31, 2016 , ... Super Powder, a ... to on the go individuals and dedicated athletes, continues to transform the nutritional supplement ... with whey, pea and milk protein, branched-chain amino acids (BCAA), alkaline minerals, wheat grass, ...
Breaking Medicine News(10 mins):
(Date:5/26/2016)... 26, 2016   Change Healthcare , ... network solutions and technology-enabled services designed to ... into a strategic channel partnership with SourceMed, ... solutions and revenue cycle management services that ... rehabilitation clinics to optimize revenue, operational efficiency ...
(Date:5/25/2016)... FDA 510(k) clearance covers Confocal Miniprobes ... and surgical applications Mauna Kea Technologies ... multidisciplinary confocal laser endomicroscopy (CLE) platform, today announced ... the 12 th 510(k) clearance from United ... FDA clearance covers Confocal Miniprobes indicated for use ...
(Date:5/25/2016)... Deutschland und GERMANTOWN, Maryland , ... Zusammenarbeit mit Therawis bedient dringenden ...   QIAGEN N.V. (NASDAQ: ... bekannt, eine Lizenz- und Entwicklungsvereinbarung mit Therawis Diagnostics ... die Onkologie eingegangen zu sein. Ein erstes Projekt ...
Breaking Medicine Technology: