Navigation Links
Indian Scientists Identify New Way Of Combating TB

Scientists belonging to India’s National Institute of Immunology are reported to have identified an important element which helps us to understand how the tuberculosis (TB) bacteria survives in the human body. // This will help in developing newer and more effective medicines to combat the disease, which claims as many as 2 million lives across the world annually. The research team led by Rajesh S. Gokhale have identified the genes that enable the mycobacterium tuberculosis to acquire the iron it needs to grow and promote the infection of the disease in humans. This discovery will contribute towards combating the multi-drug resistant tuberculosis.

Iron is essential for the mycobacterium to survive and for its enzymatic action, according to Gokhale. It takes the iron from the host cell and to get it the mycobacterium develops siderophores, molecules synthesized by it for its own utility. The new anti-TB drugs being developed can use this pathway to attack the mycobacterium.

When the mycobacterium infects humans, it takes up residence in immune cells called macrophages. To survive in this harsh environment, the mycobacterium, like many other types of bacteria, need iron to carry out life-sustaining functions, such as creating proteins and synthesizing nucleotides to form DNA.

Gokhale's group identified the location of the genes that help the mycobacterium gather the iron more efficiently by observing that the expression of the genes, which increased significantly in response to low iron concentrations.

Edited (IANS)
'"/>




Page: 1

Related medicine news :

1. Indian Prime Minister has successful Knee Replacement Surgery
2. Development of AIDS vaccine -- Chiron Corp in talks with four Indian cos
3. Indian Doctor granted US patent on organ regeneration
4. Heart attack kills one in every 10 Indians
5. Indian Cherry: Richest Source of Vitiamin C
6. Indian Nationals with Foreign Medical Degrees can now practice in India
7. An Indian Bride with signs of SARS
8. Are Indians aware of SARS ?
9. Indians Stay Away from Coke, Pepsi After Toxin Scare
10. Indian pharma industry upbeat on WTO drug deal
11. Indian Treatment for Iraqi Babies
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/24/2017)... ... March 24, 2017 , ... In just two ... Frame vertical micro-veggies garden on Kickstarter . Surpassing the $100,000 milestone so ... nearly 2,000 consumers (and counting) already backing the campaign. , “We are ...
(Date:3/24/2017)... NY (PRWEB) , ... March 24, 2017 , ... The ... and White Plains, N.Y., is pleased to announce Westchester resident Lauren C. Enea has ... law clerk for the firm, will concentrate her practice in elder law, Medicaid planning ...
(Date:3/24/2017)... ... March 24, 2017 , ... Judy Buchanan, co-owner of Serenity ... MD. Judy says, “I am passionate about sharing Reiki as a holistic, complementary ... and challenging time.” , A Certified Medical Reiki™ Master trained by Raven Keys ...
(Date:3/24/2017)... ... March 24, 2017 , ... “The Communion of Saints: A ... God in congregations across the United States. “The Communion of Saints” is ... who has served congregations in seven states throughout his long career of devotion ...
(Date:3/23/2017)... ... March 23, 2017 , ... The physicians of KSF Orthopaedic ... greater Houston Area. The new location is located at 2255 E. Mossy Oaks Rd., ... Village. This newest location will provide patients living in the north Houston area (The ...
Breaking Medicine News(10 mins):
(Date:3/23/2017)... Research and Markets has announced the addition ... Replacement Procedure By Technique, Repair Procedure By Technique, By Region, By ... ... forecasted to grow at a CAGR of 13.35% during 2016-2021 ... rising aging population, growth in population with heart disease and rising ...
(Date:3/23/2017)... , March 23, 2017 ... report created through extensive primary research (inputs from ... report aims to present the analysis of global ... Procedure (Replacement and Repair); Replacement Procedure By Technique ... By Technique (Surgical Devices, Balloon Valvuloplasty, Transcatheter Mitral ...
(Date:3/23/2017)... 23, 2017 As a result of ... the prevalence of allergic diseases, cutting edge developments ... revolutionising the ways in which pharmaceutical and biotech ... promises to be both a high quality meeting ... interest groups, immunologists, research scholars and doctors. The ...
Breaking Medicine Technology: