Navigation Links
Indian Scientists Identify New Way Of Combating TB

Scientists belonging to India’s National Institute of Immunology are reported to have identified an important element which helps us to understand how the tuberculosis (TB) bacteria survives in the human body. // This will help in developing newer and more effective medicines to combat the disease, which claims as many as 2 million lives across the world annually. The research team led by Rajesh S. Gokhale have identified the genes that enable the mycobacterium tuberculosis to acquire the iron it needs to grow and promote the infection of the disease in humans. This discovery will contribute towards combating the multi-drug resistant tuberculosis.

Iron is essential for the mycobacterium to survive and for its enzymatic action, according to Gokhale. It takes the iron from the host cell and to get it the mycobacterium develops siderophores, molecules synthesized by it for its own utility. The new anti-TB drugs being developed can use this pathway to attack the mycobacterium.

When the mycobacterium infects humans, it takes up residence in immune cells called macrophages. To survive in this harsh environment, the mycobacterium, like many other types of bacteria, need iron to carry out life-sustaining functions, such as creating proteins and synthesizing nucleotides to form DNA.

Gokhale's group identified the location of the genes that help the mycobacterium gather the iron more efficiently by observing that the expression of the genes, which increased significantly in response to low iron concentrations.

Edited (IANS)
'"/>




Page: 1

Related medicine news :

1. Indian Prime Minister has successful Knee Replacement Surgery
2. Development of AIDS vaccine -- Chiron Corp in talks with four Indian cos
3. Indian Doctor granted US patent on organ regeneration
4. Heart attack kills one in every 10 Indians
5. Indian Cherry: Richest Source of Vitiamin C
6. Indian Nationals with Foreign Medical Degrees can now practice in India
7. An Indian Bride with signs of SARS
8. Are Indians aware of SARS ?
9. Indians Stay Away from Coke, Pepsi After Toxin Scare
10. Indian pharma industry upbeat on WTO drug deal
11. Indian Treatment for Iraqi Babies
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Indian Scientists Identify New Way Combating

(Date:7/26/2014)... July 26, 2014 As the ... the true vision of Xoçai is ... its exclusive and healthy chocolate products. One such ... of cacao, açaí berries and blueberries, an ingredient ... high-antioxidant blend is utilized in all of Xoçai ...
(Date:7/25/2014)... Dental Perfection, a Derby cosmetic dentist ... general dentistry, clear braces and much more, has just ... in Derby. The new practice, which is scheduled to ... in Littleover, Derby. Patients may already pre-register for the ... dental practice, which is headed by Invisalign specialist and ...
(Date:7/25/2014)... Dallas, Texas (PRWEB) July 26, 2014 ... Global and China Gel Permeation Chromatography Industry” ... on the Global and China Gel Permeation ... Permeation Chromatography information, including Gel Permeation Chromatography ... as well as industry overview. This research ...
(Date:7/25/2014)... July 25, 2014 In recent years, men ... eager to reverse the symptoms associated with age-related testosterone decline. ... at large, a new case study from Renew ... of testosterone therapy using bioidentical hormones. , The case ... from Seattle who found himself beginning to feel the effects ...
(Date:7/25/2014)... American motor vehicle owners who are at higher ... premiums for vehicle insurance on average. The Quotes Pros ... SR22 insurance for high risk motorists this year at ... of local agencies providing direct price quotations for risk ... available for any car owner to access. One advantage ...
Breaking Medicine News(10 mins):Health News:Xocai-Asia Japanese Distributors in Hachioji, Japan Sanction Local Single-Source-Chocolate Investigative Report: MXI-Corp-Asia Discloses Direct-Sales Compensation Plan 2Health News:Xocai-Asia Japanese Distributors in Hachioji, Japan Sanction Local Single-Source-Chocolate Investigative Report: MXI-Corp-Asia Discloses Direct-Sales Compensation Plan 3Health News:Xocai-Asia Japanese Distributors in Hachioji, Japan Sanction Local Single-Source-Chocolate Investigative Report: MXI-Corp-Asia Discloses Direct-Sales Compensation Plan 4Health News:Derby Cosmetic Dentist Dental Perfection to Open New Practice in Littleover, Derby this September 2Health News:2014 China & Global GPC Industry - Gel Permeation Chromatography Development Trends Now at DeepResearchReports.com 2Health News:2014 China & Global GPC Industry - Gel Permeation Chromatography Development Trends Now at DeepResearchReports.com 3Health News:New Case Study Highlights Effectiveness of Testosterone Therapy in Fighting Weight Gain and Fatigue 2Health News:New Case Study Highlights Effectiveness of Testosterone Therapy in Fighting Weight Gain and Fatigue 3Health News:SR22 Insurance for High Risk Motorists Added to Local Quotes System at Insurer Website Online 2
... , , , ... Costs Will Increase , , ... Director Douglass Elmendorf about current legislative drafts proposed by the Senate and ... care costs in the U.S. -- chronic disease. , ...
... the treatment of disease ,The team, led ... Research at the University of Copenhagen and the Max Planck ... in 1,750 different proteins. "This is more than ... of known acetylation switches by a factor of six, and ...
... prevention, treatment and care throughout Europe by improving communications within ... the launch of a new website: www.eurocancercoms.eu . The ... from researchers and doctors to patients. The ... Oncology and is led by ECCO the European CanCer ...
... only four sites across the country to participate in a ... investigate the effectiveness of a chemotherapeutic agent, ThermoDox, used in ... treating recurrent chest wall breast cancer. Recurrent chest ... on the chest wall, most commonly presenting in the skin ...
... are diagnosed with pancreatic cancer. Few live very long, ... after diagnosis. There,s new hope, though, from the ... University,s Faculty of Life Sciences. His drug compound Salirasib ... passed Phase I/II clinical trials. The drug, given in ...
... at Ben-Gurion University of the Negev (BGU) have conducted a ... adolescents, demonstrating that strong social support from friends is a ... to be the first of its type, was published in ... The American Academy of Pediatrics. ...
Cached Medicine News:Health News:PFCD Urges Congress to Address Real Cost-Driver in Health Reform in Light of New CBO Statement 2Health News:New Web site launches $1.7 million project to improve European cancer communications 2Health News:New Web site launches $1.7 million project to improve European cancer communications 3Health News:RI Hospital first in country to enroll patient in new study for recurrent chest wall breast cancer 2Health News:New drug candidate prolongs the lives of pancreatic cancer patients 2Health News:Social support buffers adolescent depression after terrorist attacks: Ben-Gurion University 2
(Date:7/25/2014)... 25, 2014 Research and Markets ... Diagnostic Devices Market 2014-2018" report to their offering. ... About Ophthalmic Diagnostic Device An ophthalmic ... a defect or deficiency in the human visual pathway. ... such as presbyopia, cataracts, glaucoma, retinal disorders, conjunctivitis, and ...
(Date:7/25/2014)... Ore. , July 25, 2014  Semler ... an emerging medical risk assessment company that develops ... patients and evaluating chronic diseases, today reported financial ... ended June 30, 2014. "The ... for Semler," said Doug Murphy-Chutorian , M.D., ...
(Date:7/25/2014)... , July 25, 2014  Arena Pharmaceuticals, Inc. ... provide a corporate update and report second quarter 2014 ... on Friday, August 1, 2014. That same day, Arena ... a.m. Eastern Time (5:30 a.m. Pacific Time). ... 877.643.7155 for domestic callers and 914.495.8552 for international callers. ...
Breaking Medicine Technology:Global Ophthalmic Diagnostic Devices Market 2014-2018: Key Vendors are Alcon, Carl Zeiss, Haag-Streit and Topcon 2Semler Reports Second Quarter 2014 Financial Results 2Semler Reports Second Quarter 2014 Financial Results 3Arena Pharmaceuticals to Host Corporate Update and Financial Results Conference Call and Webcast on Friday, August 1 2Arena Pharmaceuticals to Host Corporate Update and Financial Results Conference Call and Webcast on Friday, August 1 3
... 10, 2011 Sildenafil, a drug used to ... possible use -- helping children and young adults ... Sildenafil significantly improved measures of exercise performance during ... according to researchers from The Children,s Hospital of ...
... seek ways to reduce Medicaid spending, they should start by ... model to the more efficient model used in some parts ... finds that the program could save $473 million over ... more like those in Medicare and commercial plans. Governors Chris ...
Cached Medicine Technology:Exercise Performance in Children and Young Adults with Single Ventricle Heart Disease Improves with Use of Drug for Erectile Dysfunction 2Exercise Performance in Children and Young Adults with Single Ventricle Heart Disease Improves with Use of Drug for Erectile Dysfunction 3Budget Solution? Modernizing Medicaid Pharmacy Could Save Florida $473 Million 2
PDA format of the well-known standard antimicrobial reference....
PDA application providing a complete guide for the diagnosis and management of electrolyte disorders....
Contains the most common procedures from all orthopedic sub-specialties organized by body area....
Consists of the print and PDA versions of Harrison's Manual of Medicine 15th Edition. Provides high-end medical content via PDA....
Medicine Products: