Navigation Links
Indian Scientists Identify Cataract Causing Genes

A joint study by the Indian and foreign scientists have claimed that they have identified three new cataract-causing genes, which are often carried // on for many generations in families in India.

Scientists from the Center for Genetic Disorders of Guru Nanak Dev University in collaboration with researchers from the National Institute of Health, USA and the Institute of Human Genetics in Berlin have claimed after 30 years of research in the field of ophthalmology, to discover three genes that cause cataracts.

The research team led by Dr Jai Rup Singh the Coordinator at the Center for Genetic Disorders achieved the breakthrough by identifying and localizing the genes in Indian families. It was stated that the three genes identified by the scientists cause fan-shaped cataract, cerulean cataract and sutural cataract. Dr Jai Rup Singh, while releasing his research work among press, stated that this research had been carried out on congenital cataract for the past 30 years.

Explaining that they had collected DNA samples from more than 2,400 persons suffering from genetic disease of the eye, he said that the DNA analysis on these cases was initiated in 1990. He further stated that the DNA analysis on many more families with congenital cataract is still in progress. Singh explained that the first breakthrough came in 2001 when two new genes were identified. The first of these, was a fan-shaped cataract gene that is caused by a single nucleotide alteration which changes the structure of alpha-crystalline, an essential lens protein, ultimately leading to congenital cataract that is associated with micro cornea.

The second cataract-causing gene that leads to Cerulean Cataract was discovered during molecular studies by Singh’s team that identified a new type of mutation found in a family of three generations. Singh explained that they found that in this case the replacement of Lysine, an amino acid, with Arginine was found to ul timate lead to Cerulean cataract. He also stated that, the two genes, along with a newly discovered third, have been localized to Indian families.

Singh said that congenital cataract affected about three per 10,000 newborns and was one of the significant causes of blindness in children and often led to life-long visual disability. There is hope that with this discovery there could be a possible breakthrough in finding possible cures for the disease that affects many newborns causing blindness and other visual problems.

Related medicine news :

1. Indian Prime Minister has successful Knee Replacement Surgery
2. Development of AIDS vaccine -- Chiron Corp in talks with four Indian cos
3. Indian Doctor granted US patent on organ regeneration
4. Heart attack kills one in every 10 Indians
5. Indian Cherry: Richest Source of Vitiamin C
6. Indian Nationals with Foreign Medical Degrees can now practice in India
7. An Indian Bride with signs of SARS
8. Are Indians aware of SARS ?
9. Indians Stay Away from Coke, Pepsi After Toxin Scare
10. Indian pharma industry upbeat on WTO drug deal
11. Indian Treatment for Iraqi Babies
Post Your Comments:

(Date:12/1/2015)... ... December 01, 2015 , ... Baptist ... the U.S. and is the only hospital in the region providing what is ... presentation of transcatheter pacing patients were revealed recently at a medical conference and ...
(Date:12/1/2015)... (PRWEB) , ... December 01, 2015 , ... ... however, there are professionals who believe that with innovative technologies and under the ... the patient to get the benefit of a dual-approach to his or her ...
(Date:12/1/2015)... ... December 01, 2015 , ... December 1, ... vast improvements in scientific research and discoveries, leading us to better understand the ... relief to those affected by HIV/AIDS. Mediaplanet’s cross-platform edition of “World AIDS Day” ...
(Date:12/1/2015)... ... December 01, 2015 , ... The workstation boundaries for imaging ... Information Systems launches MED-TAB™ -- the world’s first portable DICOM-calibrated medical image display, ... to December 4, 2015. , MED-TAB is expected to change teleradiology because ...
(Date:12/1/2015)... , ... December 01, 2015 , ... ... radiographic technicians must mark the film for accurate interpretation by the radiologist. The ... Fortunately, an inventor from Sacramento, Calif., has found a way to alleviate this ...
Breaking Medicine News(10 mins):
(Date:12/1/2015)... Va. , Dec. 1, 2015 As ... Drug Supply Chain Security Act (DSCSA) approaches, ... small and independent pharmacies comply with looming FDA ... InfiniTrak is entering endorsement agreements with State ... pharmacy services administration organization (PSAO) to exclusively provide ...
(Date:12/1/2015)... 2015  CytoSorbents Corporation (NASDAQ: CTSO ), ... blood purification technology to reduce deadly uncontrolled inflammation ... that Dr. Phillip Chan , President & ... the LD Micro Main Event 2015 and the ... which will be held in December. ...
(Date:12/1/2015)... A federal court has denied the state of ... filed by the Pharmaceutical Care Management Association (PCMA) challenging the ... law that forces employers and consumers to pay drugstores higher ... must now defend a law that raises health care ... Mark Merritt . --> Arkansas ...
Breaking Medicine Technology: