Navigation Links
Indian Scientists Identify Cataract Causing Genes

A joint study by the Indian and foreign scientists have claimed that they have identified three new cataract-causing genes, which are often carried // on for many generations in families in India.

Scientists from the Center for Genetic Disorders of Guru Nanak Dev University in collaboration with researchers from the National Institute of Health, USA and the Institute of Human Genetics in Berlin have claimed after 30 years of research in the field of ophthalmology, to discover three genes that cause cataracts.

The research team led by Dr Jai Rup Singh the Coordinator at the Center for Genetic Disorders achieved the breakthrough by identifying and localizing the genes in Indian families. It was stated that the three genes identified by the scientists cause fan-shaped cataract, cerulean cataract and sutural cataract. Dr Jai Rup Singh, while releasing his research work among press, stated that this research had been carried out on congenital cataract for the past 30 years.

Explaining that they had collected DNA samples from more than 2,400 persons suffering from genetic disease of the eye, he said that the DNA analysis on these cases was initiated in 1990. He further stated that the DNA analysis on many more families with congenital cataract is still in progress. Singh explained that the first breakthrough came in 2001 when two new genes were identified. The first of these, was a fan-shaped cataract gene that is caused by a single nucleotide alteration which changes the structure of alpha-crystalline, an essential lens protein, ultimately leading to congenital cataract that is associated with micro cornea.

The second cataract-causing gene that leads to Cerulean Cataract was discovered during molecular studies by Singh’s team that identified a new type of mutation found in a family of three generations. Singh explained that they found that in this case the replacement of Lysine, an amino acid, with Arginine was found to ul timate lead to Cerulean cataract. He also stated that, the two genes, along with a newly discovered third, have been localized to Indian families.

Singh said that congenital cataract affected about three per 10,000 newborns and was one of the significant causes of blindness in children and often led to life-long visual disability. There is hope that with this discovery there could be a possible breakthrough in finding possible cures for the disease that affects many newborns causing blindness and other visual problems.
'"/>




Related medicine news :

1. Indian Prime Minister has successful Knee Replacement Surgery
2. Development of AIDS vaccine -- Chiron Corp in talks with four Indian cos
3. Indian Doctor granted US patent on organ regeneration
4. Heart attack kills one in every 10 Indians
5. Indian Cherry: Richest Source of Vitiamin C
6. Indian Nationals with Foreign Medical Degrees can now practice in India
7. An Indian Bride with signs of SARS
8. Are Indians aware of SARS ?
9. Indians Stay Away from Coke, Pepsi After Toxin Scare
10. Indian pharma industry upbeat on WTO drug deal
11. Indian Treatment for Iraqi Babies
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/26/2016)... ... June 27, 2016 , ... Quality metrics are proliferating in cancer care, ... remain in the eye of the beholder, according to experts who offered insights and ... Journal of Managed Care. For the full issue, click here . , For ...
(Date:6/26/2016)... Lake Orion, Clarkston, Michigan (PRWEB) , ... June ... ... direction with respect to fertility once they have been diagnosed with endometriosis. These ... tolerable intercourse but they also require a comprehensive approach that can help for ...
(Date:6/25/2016)... ... ... First Choice Emergency Room , the largest network of independent freestanding ... of its new Mesquite-Samuell Farm facility. , “We are pleased to announce Dr. ... James M. Muzzarelli, Executive Medical Director of First Choice Emergency Room. , Dr. ...
(Date:6/24/2016)... ... ... A recent article published June 14 on E Online details ... to state that individuals are now more comfortable seeking to undergo not only the ... and cheek reduction. The Los Angeles area medical group, Beverly Hills Physicians (BHP) notes ...
(Date:6/24/2016)... ... June 24, 2016 , ... Global law firm Greenberg Traurig, P.A. announced that ... chosen by their peers for this recognition are considered among the top 2 percent ... special honors as members of this year’s Legal Elite Hall of Fame: Miami ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016  In a startling report released ... failing their residents by lacking a comprehensive, proven plan to eliminate ... a definitive ranking of how states are tackling the worst drug ... only four states – Kentucky , ... Vermont . Of the 28 failing states, three – ...
(Date:6/23/2016)... June 23, 2016 Capricor ... ), a biotechnology company focused on the discovery, ... that patient enrollment in its ongoing randomized HOPE-Duchenne ... exceeded 50% of its 24-patient target. Capricor expects ... third quarter of 2016, and to report top ...
(Date:6/23/2016)... , June 23, 2016 , ... on Thursday, July 7, 2016 , , , , LOCATION: ... , , , , EXPERT PANELISTS:  , , , ... Senior Industry Analyst, Christi Bird; Senior Industry Analyst, Divyaa Ravishankar and ... The global pharmaceutical industry is witnessing an exceptional era. ...
Breaking Medicine Technology: