Navigation Links
Indian Scientists Identify Cataract Causing Genes

A joint study by the Indian and foreign scientists have claimed that they have identified three new cataract-causing genes, which are often carried // on for many generations in families in India.

Scientists from the Center for Genetic Disorders of Guru Nanak Dev University in collaboration with researchers from the National Institute of Health, USA and the Institute of Human Genetics in Berlin have claimed after 30 years of research in the field of ophthalmology, to discover three genes that cause cataracts.

The research team led by Dr Jai Rup Singh the Coordinator at the Center for Genetic Disorders achieved the breakthrough by identifying and localizing the genes in Indian families. It was stated that the three genes identified by the scientists cause fan-shaped cataract, cerulean cataract and sutural cataract. Dr Jai Rup Singh, while releasing his research work among press, stated that this research had been carried out on congenital cataract for the past 30 years.

Explaining that they had collected DNA samples from more than 2,400 persons suffering from genetic disease of the eye, he said that the DNA analysis on these cases was initiated in 1990. He further stated that the DNA analysis on many more families with congenital cataract is still in progress. Singh explained that the first breakthrough came in 2001 when two new genes were identified. The first of these, was a fan-shaped cataract gene that is caused by a single nucleotide alteration which changes the structure of alpha-crystalline, an essential lens protein, ultimately leading to congenital cataract that is associated with micro cornea.

The second cataract-causing gene that leads to Cerulean Cataract was discovered during molecular studies by Singh’s team that identified a new type of mutation found in a family of three generations. Singh explained that they found that in this case the replacement of Lysine, an amino acid, with Arginine was found to ul timate lead to Cerulean cataract. He also stated that, the two genes, along with a newly discovered third, have been localized to Indian families.

Singh said that congenital cataract affected about three per 10,000 newborns and was one of the significant causes of blindness in children and often led to life-long visual disability. There is hope that with this discovery there could be a possible breakthrough in finding possible cures for the disease that affects many newborns causing blindness and other visual problems.
'"/>




Related medicine news :

1. Indian Prime Minister has successful Knee Replacement Surgery
2. Development of AIDS vaccine -- Chiron Corp in talks with four Indian cos
3. Indian Doctor granted US patent on organ regeneration
4. Heart attack kills one in every 10 Indians
5. Indian Cherry: Richest Source of Vitiamin C
6. Indian Nationals with Foreign Medical Degrees can now practice in India
7. An Indian Bride with signs of SARS
8. Are Indians aware of SARS ?
9. Indians Stay Away from Coke, Pepsi After Toxin Scare
10. Indian pharma industry upbeat on WTO drug deal
11. Indian Treatment for Iraqi Babies
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... PurhealthRX , a ... utilizing Purzorb™ technology. Applying the Purzorb™process to full spectrum CBD oil will revolutionize the ... a CBD form that can be easily incorporated into liquid products, while reducing costs ...
(Date:10/13/2017)... Shelton, CT (PRWEB) , ... October 13, 2017 , ... ... and long-term care services, staged a mock evacuation of the facility as part of ... Department, Shelton Fire Department, Echo Hose EMS and Shelton City Emergency Manager, as well ...
(Date:10/13/2017)... ... October 13, 2017 , ... Ellevate Network, the leading network for professional women, ... towards gender equality at their inaugural Summit in New York City in June. The ... social audience of over 3 million. To watch the Mobilize Women video, click ...
(Date:10/13/2017)... ... 2017 , ... Talented host, actor Rob Lowe, is introducing ... new episode of "Success Files," which is an award-winning educational program broadcasted on ... subject in-depth with passion and integrity. , Sciatica occurs when the sciatic nerve ...
(Date:10/13/2017)... ... October 13, 2017 , ... “America On The Brink”: the ... “America On The Brink” is the creation of published author, William Nowers. Captain ... As a WWII veteran, he spent thirty years in the Navy. Following his ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... Mich. , Oct. 2, 2017 Diplomat ... 8th Day Software and Consulting, LLC , and ... 8th Day Software, based in Tennessee ... LLC. 8th Day expands EnvoyHealth,s service offerings for health ... development. "In an ...
(Date:10/2/2017)... Oct. 2, 2017 The Rebound mobile app is ... to reverse the tide of prescription drug addiction. The app ... medicine intake and stepping down their dosage in a safe, ... in December 2017; the first 100,000 people to sign up ... http://www.rebound-solution.com/ ...
(Date:9/27/2017)... Israel and NEW YORK , Sept. 27, ... with mobile health and big data solutions, today announced that its MyDario ... Please check your local TV listings for when The Dr. Oz Show ... ... season this month. ...
Breaking Medicine Technology: