Navigation Links
Increase in Pneumococcal Infections That are Not Covered by Vaccine

Children, native of Alaska, are experiencing increased rates of serious infections caused by strains of pneumococcal bacteria that are not covered by the current childhood pneumococcal vaccine,// according to a study.

Before introduction of 7-valent pneumococcal conjugate vaccine (PCV7), Alaska Native children and adults experienced high rates of invasive pneumococcal disease (IPD) compared with non–Native Alaskans. Introduction of PCV7 into the routine childhood vaccination schedule in 2001 resulted in decreases in vaccine-type IPD and consequent decreases in all IPD among U.S. children, according to background information in the article. With the introduction of PCV7, one concern has been the potential for nonvaccine serotypes to emerge and diminish the disease prevention gains made through the use of PCV7.

Rosalyn J. Singleton, M.D., M.P.H., of the Centers for Disease Control and Prevention, Anchorage, and colleagues evaluated IPD in Alaska children for evidence of the emergence of nonvaccine serotype disease. The researchers conducted a statewide population-based laboratory surveillance of invasive Streptococcus pneumoniae infections (such as pneumonia, meningitis, or bacteremia [bacteria in the blood stream]) from January 1, 1995, through December 31, 2006.

The authors found that in the three years after introduction of PCV7 (2001-2003), IPD decreased 67 percent among Alaska Native children younger than 2 years and 61 percent in non–Native Alaska children in the same age group. Between 2001-2003 and 2004-2006, IPD rates did not change for non–Native Alaska children younger than 2 years but increased 82 percent among Alaska Native children so that the overall IPD reduction in these children was only 39 percent during 2004-2006 compared to before vaccine introduction. Since 2004, the invasive pneumococcal disease rate caused by nonvaccine serotypes has increased 140 percent compared with the prevaccine period (from 95.1 per 100 ,000 in 1995-2000 to 228.6 in 2004-2006). During the same period, there was a 96 percent decrease in heptavalent vaccine serotype disease.

"The rapid success of PCV7 in Alaska has led to the near elimination of PCV7-serotype disease and elimination of a health disparity for types covered by the vaccine. However, for Alaska Native children there now exists a substantially elevated risk for IPD from serotypes not contained in PCV7. The demonstration of replacement IPD in Alaska Native children may signify a limit to the usefulness of the currently available vaccine and emphasizes the importance of development of extended valency vaccines or vaccines not dependent on serotype-specific prevention. These data also highlight the value of continued surveillance and other epidemiological investigations to monitor the effects of pneumococcal vaccines," the authors conclude.

Source-Eurekalert
'"/>




Related medicine news :

1. Use of Cellular Phones associated with Increased risk of Brain Tumors
2. Increase in sugar...decrease in brain function!!!
3. Increase in tobacco deaths
4. Increased Heart Attack Risk From Celebrex,Vioxx
5. Deep Sleep Doesnt Increase Memory
6. Allergy Risk Increased by Kerosene Use
7. IVF technique May Increase The Risk Of Birth Defects
8. Step Aerobics Increases good cholesterol
9. Increase in renal problems
10. Fewer teeth & Increased Ischemic Stroke risk
11. Painkillers Increase Risk of Miscarriage
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... June 19, ... the dangers associated with chronic pain and the benefits of holistic treatments, Serenity ... who are suffering with Sickle Cell Disease. , Sickle Cell Disease (SCD) is a ...
(Date:6/24/2016)... ... 2016 , ... The Pulmonary Hypertension Association (PHA) learned during ... two significant new grants to support its work to advance research and patient ... recognizing patients, medical professionals and scientists for their work in fighting pulmonary hypertension ...
(Date:6/24/2016)... ... June 24, 2016 , ... Dr. Amanda Cheng, an ... Cheng has extensive experience with all areas of orthodontics, including robotic Suresmile technology, ... , Micro-osteoperforation is a revolutionary adjunct to orthodontic treatment. It can be ...
(Date:6/24/2016)... ... ... makers of Topricin and MyPainAway Pain Relief Products, join The ‘Business for a Fair Minimum ... by 2020 and then adjusting it yearly to increase at the same rate as the ... wage floor does not erode again, and make future increases more predictable. , The company ...
(Date:6/24/2016)... ... 24, 2016 , ... EB Medicine presented its first-ever “Issue ... conference in Ponte Vedra Beach, FL. The awards honor the outstanding work of ... and Pediatric Emergency Medicine Practice. , “With this award, we recognize the ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016 ... Markets has announced the addition of the " ... offering. This ... and provides an updated review, including its applications in ... the total market, which includes three main industries: pharmaceutical ...
(Date:6/24/2016)... BEIJING , June 24, 2016 Dehaier ... or the "Company"), which develops, markets and sells medical ... China , signed a strategic cooperation agreement with ... as "Hongyuan Supply Chain") on June 20, 2016, to ... Under the strategic cooperation agreement, Dehaier will leverage Hongyuan ...
(Date:6/24/2016)... 2016 According to a new ... Pen Needles, Safety Pen Needles), Needle Length (4mm, 5mm, ... Mode of Purchase (Retail, Non-Retail) - Trends & Global ... the market for the forecast period of 2016 to ... Billion by 2021 from USD 1.65 Billion in 2016, ...
Breaking Medicine Technology: