Navigation Links
Increase in Pneumococcal Infections That are Not Covered by Vaccine

Children, native of Alaska, are experiencing increased rates of serious infections caused by strains of pneumococcal bacteria that are not covered by the current childhood pneumococcal vaccine,// according to a study.

Before introduction of 7-valent pneumococcal conjugate vaccine (PCV7), Alaska Native children and adults experienced high rates of invasive pneumococcal disease (IPD) compared with non–Native Alaskans. Introduction of PCV7 into the routine childhood vaccination schedule in 2001 resulted in decreases in vaccine-type IPD and consequent decreases in all IPD among U.S. children, according to background information in the article. With the introduction of PCV7, one concern has been the potential for nonvaccine serotypes to emerge and diminish the disease prevention gains made through the use of PCV7.

Rosalyn J. Singleton, M.D., M.P.H., of the Centers for Disease Control and Prevention, Anchorage, and colleagues evaluated IPD in Alaska children for evidence of the emergence of nonvaccine serotype disease. The researchers conducted a statewide population-based laboratory surveillance of invasive Streptococcus pneumoniae infections (such as pneumonia, meningitis, or bacteremia [bacteria in the blood stream]) from January 1, 1995, through December 31, 2006.

The authors found that in the three years after introduction of PCV7 (2001-2003), IPD decreased 67 percent among Alaska Native children younger than 2 years and 61 percent in non–Native Alaska children in the same age group. Between 2001-2003 and 2004-2006, IPD rates did not change for non–Native Alaska children younger than 2 years but increased 82 percent among Alaska Native children so that the overall IPD reduction in these children was only 39 percent during 2004-2006 compared to before vaccine introduction. Since 2004, the invasive pneumococcal disease rate caused by nonvaccine serotypes has increased 140 percent compared with the prevaccine period (from 95.1 per 100 ,000 in 1995-2000 to 228.6 in 2004-2006). During the same period, there was a 96 percent decrease in heptavalent vaccine serotype disease.

"The rapid success of PCV7 in Alaska has led to the near elimination of PCV7-serotype disease and elimination of a health disparity for types covered by the vaccine. However, for Alaska Native children there now exists a substantially elevated risk for IPD from serotypes not contained in PCV7. The demonstration of replacement IPD in Alaska Native children may signify a limit to the usefulness of the currently available vaccine and emphasizes the importance of development of extended valency vaccines or vaccines not dependent on serotype-specific prevention. These data also highlight the value of continued surveillance and other epidemiological investigations to monitor the effects of pneumococcal vaccines," the authors conclude.

Source-Eurekalert
'"/>




Related medicine news :

1. Use of Cellular Phones associated with Increased risk of Brain Tumors
2. Increase in sugar...decrease in brain function!!!
3. Increase in tobacco deaths
4. Increased Heart Attack Risk From Celebrex,Vioxx
5. Deep Sleep Doesnt Increase Memory
6. Allergy Risk Increased by Kerosene Use
7. IVF technique May Increase The Risk Of Birth Defects
8. Step Aerobics Increases good cholesterol
9. Increase in renal problems
10. Fewer teeth & Increased Ischemic Stroke risk
11. Painkillers Increase Risk of Miscarriage
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/31/2016)... ... 31, 2016 , ... To meet a growing demand for ... The University of Scranton is adding a Certificate in Health Informatics to its ... rapidly growing field of healthcare information. , Healthcare organizations are under growing ...
(Date:5/30/2016)... ... 30, 2016 , ... As the CDC relaxes its stance on traditional No-Nit ... keep their households lice free. , According to a May 26 article from ... kids in the classroom despite the fact that they may be harboring an infestation. ...
(Date:5/30/2016)... ... May 30, 2016 , ... Shaolin Institute officially starts the ... special intensive summer training camp starts on June 17th on Shaolin Institute Atlanta ... children a fun and unique experience with an opportunity to learn KungFu martial ...
(Date:5/29/2016)... ... May 29, 2016 , ... Whole Health Supply is happy to ... KP-240L clipper is available to the public. This is an unusual clipper because it ... the average clipper. , Everything about this product is concentrated on ease of use, ...
(Date:5/28/2016)... (PRWEB) , ... May 28, 2016 , ... "Color Grading ... drag and drop a preset onto their media," said Christina Austin - CEO of ... Studios, editors can quickly and easily add stylish color grades to their footage. A ...
Breaking Medicine News(10 mins):
(Date:5/30/2016)... , May 30, 2016 On ... eliminate viral hepatitis by 2030. At the 69 th ... ever Global Viral Hepatitis Strategy, signalling the greatest global commitment ... a goal of eliminating hepatitis B and C by 2030 ... if reached, will reduce annual deaths by 65% and increase ...
(Date:5/27/2016)... 27, 2016  A new study highlights the necessity of health literacy within the ... the American College of Radiology , a majority of oncology patients undergo imaging screenings ... http://photos.prnewswire.com/prnh/20160527/373022 ... ... Medical Diagnostic Imaging Ampronix ...
(Date:5/27/2016)... 27, 2016 Kitov ... focused on late-stage drug development, today announced the ... of pivotal batches required for registration of KIT-302 ... This follows Kitov,s announcement in December ... met its primary efficacy endpoint. "We ...
Breaking Medicine Technology: