Navigation Links
In Search Of A New Drug To Target Cholesterol

Based on findings of a recent study researchers say cholesterol may be actually needed to help insulate the nerves and keep cells healthy , however researchers also say that too much of it could end up in // it being warehoused inside the arteries, where it builds up as plaque and can cause heart attacks and strokes.

Researchers suggest an enzyme called ACAT2 may be to blame for the build-up. ACAT2 is one of four enzymes responsible for helping cholesterol leave the liver, where it is made, and travel to other parts of the body. ACAT2 most often helps cholesterol travel to the arteries, where it builds up into the deadly plaque.

After studying mice who were genetically altered not to produce ACAT2 researchers came to the conclusion that the mice had 85-percent less hardening of the arteries than mice who still produced the enzyme. When the normal mice were given a molecule known to block the effects of ACAT2, the same results were seen.

Researchers then studied the enzyme in monkeys, looking specifically at whether certain foods might increase the effects of ACAT2 on cholesterol. It was seen that Monkeys who were fed diets high in monounsaturated fats like those contained in olive oil and nuts -- so-called "good" fats -- actually had the same rates of heart disease as monkeys who ate saturated, or so-called "bad" fats. Thus researchers suspect that monounsaturated fats, while reducing levels of “bad” cholesterol, are more susceptible to ACAT2.

Thus in conclusion researchers say they hope that in the future their findings may one day lead to a drug to target ACAT2 in humans, thereby reducing the incidence of heart disease caused by plaque build-up in the arteries.
'"/>




Page: 1

Related medicine news :

1. In Search Of Drugs From the Ocean
2. In Search Of A New Drug To Target Cholesterol
3. Search For Bigfoot Creature To Be Delayed
4. Australia In Search Of A Better Way to Handle Critically Ill Patients and Balance Elective Surgery
5. Intensive Search On For Nurse Killer
6. Search for an Effective and Safe Hepatitis C Vaccine
7. A Futile Search for Cancer Gene
8. Search for Human Pheromone
9. Internet Searches Fail To Give Useful Information To Cancer Patients
10. Weight Loss and Intimacy -- A Search for Self
11. ‘Search and Destroy’ operation against dengue mosquitoes in Philippins
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/6/2016)... ... 2016 , ... Research has shown that building shame resilience ... and level of relapse. , At the 2016 iaedp Symposium, the ... the critical tasks of the recovery phase and beyond including relapse prevention and ...
(Date:2/5/2016)... ... February 05, 2016 , ... Love is in the ... a variety of colors, assortments and packaging. This staple for Valentine’s Day is a ... location. , For Valentine’s Day, not only are long-stem roses available, but also ...
(Date:2/5/2016)... City, UT (PRWEB) , ... February 05, 2016 , ... ... Whole-Food Nutrition , announced that the much-anticipated feature with author Jahnavi Foster, specialist in ... Humans Amateur TV Network. , Each week, on his weekly Whole-Food Warrior TV show, ...
(Date:2/5/2016)... ... February 05, 2016 , ... The event is being held ... Event Center in Minneapolis, Minn. Triumph Over Parkinson’s will fund nearly $100,000 for research ... Schneiderman’s Furniture, lives with Parkinson’s disease and is the architect of this informative event ...
(Date:2/5/2016)... Santa Rosa, CA (PRWEB) , ... February 05, ... ... are pleased to announce the addition of micro-needling services in their Napa Valley ... appearance. The founders of Plastic Surgery Associates, Dr. Canales and Dr. Furnas, are ...
Breaking Medicine News(10 mins):
(Date:2/4/2016)... 2016 Wegener Polyangiitis - Pipeline Review, ... ,Wegener Polyangiitis - Pipeline Review, H2 2015, provides ... This report provides comprehensive information on the ... analysis at various stages, therapeutics assessment by drug ... (RoA) and molecule type, along with latest updates, ...
(Date:2/4/2016)... -- Omnicell, Inc. (NASDAQ: OMCL ), a leading provider of ... announced results for its fiscal year and fourth quarter ... --> GAAP results: Revenue for the fourth quarter ... 4.1% from the third quarter of 2015, and up ... 2014. Revenue for the year ended December 31, 2015 was ...
(Date:2/4/2016)... 2016  Blueprint Medicines Corporation (NASDAQ: BPMC ... selective investigational kinase medicines for patients with genomically ... board of directors of Lonnel Coats , ... of industry-related experience. Jeffrey Albers ... strong strategic experience developing and commercializing numerous oncology ...
Breaking Medicine Technology: