Navigation Links
In Search Of A New Drug To Target Cholesterol

Based on findings of a recent study researchers say cholesterol may be actually needed to help insulate the nerves and keep cells healthy , however researchers also say that too much of it could end up in // it being warehoused inside the arteries, where it builds up as plaque and can cause heart attacks and strokes.

Researchers suggest an enzyme called ACAT2 may be to blame for the build-up. ACAT2 is one of four enzymes responsible for helping cholesterol leave the liver, where it is made, and travel to other parts of the body. ACAT2 most often helps cholesterol travel to the arteries, where it builds up into the deadly plaque.

After studying mice who were genetically altered not to produce ACAT2 researchers came to the conclusion that the mice had 85-percent less hardening of the arteries than mice who still produced the enzyme. When the normal mice were given a molecule known to block the effects of ACAT2, the same results were seen.

Researchers then studied the enzyme in monkeys, looking specifically at whether certain foods might increase the effects of ACAT2 on cholesterol. It was seen that Monkeys who were fed diets high in monounsaturated fats like those contained in olive oil and nuts -- so-called “good” fats -- actually had the same rates of heart disease as monkeys who ate saturated, or so-called “bad” fats. Thus researchers suspect that monounsaturated fats, while reducing levels of “bad” cholesterol, are more susceptible to ACAT2.

Thus in conclusion researchers say they hope that in the future their findings may one day lead to a drug to target ACAT2 in humans, thereby reducing the incidence of heart disease caused by plaque build-up in the artries.
'"/>




Page: 1

Related medicine news :

1. In Search Of Drugs From the Ocean
2. In Search Of A New Drug To Target Cholesterol
3. Search For Bigfoot Creature To Be Delayed
4. Australia In Search Of A Better Way to Handle Critically Ill Patients and Balance Elective Surgery
5. Intensive Search On For Nurse Killer
6. Search for an Effective and Safe Hepatitis C Vaccine
7. A Futile Search for Cancer Gene
8. Search for Human Pheromone
9. Internet Searches Fail To Give Useful Information To Cancer Patients
10. Weight Loss and Intimacy -- A Search for Self
11. ‘Search and Destroy’ operation against dengue mosquitoes in Philippins
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/27/2016)... ... 27, 2016 , ... An educational campaign aimed at everyone ... courtesy of awareness-driven celebrities and thought leaders. It also provides insight to the ... leaders such as Bioness. , As patients feel increasingly concerned about the ...
(Date:5/27/2016)... , ... May 27, 2016 , ... ... scholarships to students studying complementary medicine. Allison Outerbridge is this year’s Life ... award on May 18 at the university’s Student Leadership Awards ceremony. , Outerbridge ...
(Date:5/26/2016)... ... May 26, 2016 , ... Cabot Corporation, ... defective respirators, according to court documents and SEC filings. A jury has ... Tyler v. American Optical Corporation, Case No. BC588866, Los Angeles County, California. The ...
(Date:5/26/2016)... ... 2016 , ... The Woodlands at John Knox Village , Florida’s first ... for living and healing, celebrated its grand opening, today. The Woodlands at John Knox ... by Empowered Staff. , “This is an incredibly fulfilling time for John Knox Village ...
(Date:5/26/2016)... ... May 26, 2016 , ... Dr. James Maisel will ... Long Island Chapter on June 4, 2016, 1:30-3:30 pm at the Farmingdale Public ... Retina Group of New York , is a Board Certified ophthalmologist who ...
Breaking Medicine News(10 mins):
(Date:5/24/2016)... 24, 2016 ARANZ Medical  Ltd ... healthcare sector, has been named the Coretex Hi-Tech Emerging Company ... Dr Bruce Davey , CEO of ARANZ ...  It,s really good to be recognised for the work we ... are used in 35 countries around the world from Sub-Saharan ...
(Date:5/24/2016)... BioMarketing as senior vice president of sales, announced Andrea Heslin Smiley , VMS ... company,s business development and sales team, exploring new opportunities for VMS to empower patients ... ... ... ...
(Date:5/24/2016)... May 24, 2016 ... , la première endoprothèse à double ... à l,intervention portant sur les membres inférieurs ... OrbusNeich, entreprise mondiale spécialisée dans la ... la vie, a élargi son portefeuille pour ...
Breaking Medicine Technology: