Navigation Links
In Search Of A New Drug To Target Cholesterol

Based on findings of a recent study researchers say cholesterol may be actually needed to help insulate the nerves and keep cells healthy , however researchers also say that too much of it could end up in // it being warehoused inside the arteries, where it builds up as plaque and can cause heart attacks and strokes.

Researchers suggest an enzyme called ACAT2 may be to blame for the build-up. ACAT2 is one of four enzymes responsible for helping cholesterol leave the liver, where it is made, and travel to other parts of the body. ACAT2 most often helps cholesterol travel to the arteries, where it builds up into the deadly plaque.

After studying mice who were genetically altered not to produce ACAT2 researchers came to the conclusion that the mice had 85-percent less hardening of the arteries than mice who still produced the enzyme. When the normal mice were given a molecule known to block the effects of ACAT2, the same results were seen.

Researchers then studied the enzyme in monkeys, looking specifically at whether certain foods might increase the effects of ACAT2 on cholesterol. It was seen that Monkeys who were fed diets high in monounsaturated fats like those contained in olive oil and nuts -- so-called “good” fats -- actually had the same rates of heart disease as monkeys who ate saturated, or so-called “bad” fats. Thus researchers suspect that monounsaturated fats, while reducing levels of “bad” cholesterol, are more susceptible to ACAT2.

Thus in conclusion researchers say they hope that in the future their findings may one day lead to a drug to target ACAT2 in humans, thereby reducing the incidence of heart disease caused by plaque build-up in the artries.
'"/>




Page: 1

Related medicine news :

1. In Search Of Drugs From the Ocean
2. In Search Of A New Drug To Target Cholesterol
3. Search For Bigfoot Creature To Be Delayed
4. Australia In Search Of A Better Way to Handle Critically Ill Patients and Balance Elective Surgery
5. Intensive Search On For Nurse Killer
6. Search for an Effective and Safe Hepatitis C Vaccine
7. A Futile Search for Cancer Gene
8. Search for Human Pheromone
9. Internet Searches Fail To Give Useful Information To Cancer Patients
10. Weight Loss and Intimacy -- A Search for Self
11. ‘Search and Destroy’ operation against dengue mosquitoes in Philippins
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/27/2017)... ... April 27, 2017 , ... The Incentive Research Foundation ... A Nudge Guide," a groundbreaking analysis of how behavioral economics can be applied ... immediately to IRR programs, the report highlights proven behavioral economics approaches and the ...
(Date:4/27/2017)... ... April 27, 2017 , ... Thinksport, ... the heels of Thinksport’s award-winning sunscreen they’ve used the same scientific approach to ... , Countless deodorants flood the aisles that contain harmful chemicals that should be ...
(Date:4/27/2017)... ... April 27, 2017 , ... Last night, ... CAREGiverSM of the Year for her extraordinary compassion and lifelong dedication to serve ... American professional caregivers for the prestigious award each year – identifying a CAREGiver ...
(Date:4/27/2017)... ... April 27, 2017 , ... Goodcents Deli Fresh Subs announced a franchise ... area this year. , The first new location will open at the corner ... at 84th and Northern Lights Drive this fall. And the third location is in ...
(Date:4/27/2017)... (PRWEB) , ... April 27, 2017 , ... Are you ... tragic spike in water-related accidents and drownings during the summer. While most of us ... that these situations occur every day. Very few people are taking the time to ...
Breaking Medicine News(10 mins):
(Date:4/18/2017)... Cogentix Medical, Inc. (NASDAQ: CGNT), a global medical device ... markets with innovative and proprietary products, will release financial ... after the market close on Tuesday, May 2, 2017. ... call and webcast to discuss its financial results the ... p.m. Eastern Time (3:30 p.m. Central Time). Darin ...
(Date:4/18/2017)... Research and Markets has announced the addition of the "Global ... ... at a CAGR of 6.35% during the period 2017-2021. ... based on an in-depth market analysis with inputs from industry experts. ... the coming years. The report also includes a discussion of the ...
(Date:4/18/2017)... and BLOOMINGTON, Minn. , ... IMMY ) ("Imprimis"), an ophthalmology-focused pharmaceutical ... ("Precision Lens"), today announced the signing of a ... Precision Lens will deploy a dedicated sales team ... in the U.S., primarily focused in 13 states ...
Breaking Medicine Technology: