Navigation Links
Importance Of Early Diagnosis And Treatment For Muscular Dystrophy Patients

Cardiac disease is the major cause of mortality in patients with muscular dystrophy and is present in most boys with Duchenne muscular dystrophy and approximately 70 % of those with Becker muscular dystrophy. // These are the two common forms of muscular dystrophy caused by defects in a gene called dystrophin. Both are frequently associated with dilated cardiomyopathy (DCM), heart failure and premature death.

Cardiac symptoms typically appear late in the course of cardiomyopathy, in part because affected individuals are usually wheelchairchair bound and often physically inactive. Heart disease progresses quickly, leading to premature death, often before 25 years of age.

According to new research published online (October 24, 2005) in the journal Circulation, early diagnosis and treatment of DCM in DMD/BMD patients may lead to ventricular remodeling and that specific dystrophin gene mutations may predict cardiac involvement, while other mutations may protect against or inhibit development of DCM.

For the study, 69 boys, 62 with DMD and 7 with BMD were referred to the Cardiovascular Genetics Clinic for evaluation, including echocardiography and DNA analysis. Follow-up evaluations were scheduled yearly until the first abnormal echocardiogram indicative of DCM and quarterly thereafter. After the first abnormal echocardiogram, which occurred at 14-15 years, 31 boys were started on ACE inhibitor or beta blocker therapy. During the follow-up two patients remained stable with their dilated cardiomyopathy, eight showed improvement and 19 normalized both heart size and function.

The authors, from the Baylor College of Medicine (BCM) and Texas Children's Hospital in Houston add that further studies evaluating the impact of early intervention strategies on left ventricular geometry and function in muscular dystrophy patients seem warranted.
'"/>




Page: 1

Related medicine news :

1. Importance of Fatty food In Hypercholestrolemia
2. Importance of soy protein in your diet
3. Importance of type of sex in organ transplantation
4. Importance of An Active Lifestyle
5. Importance of An Active Lifestyle
6. The Importance Of “ Good ”Control Of Diabetes During Pregnanc
7. The Importance Of Skin Cancer Screening
8. The Importance Of Folic Acid Supplements
9. The Importance Of Vitamin D Supplements
10. More Importance To Be Given To Prenatal Nutrition
11. Beauty Queens Urge On The Importance Of Maintaining Bone Integrity
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/21/2017)... ... 2017 , ... Seamild, the largest manufacturer of oats in China, is now ... founder. As Oat is recognized globally as one of the healthiest cereals, XieQingkui, the ... it is a move to sow the seed of good karma. Buddhism spirit featuring ...
(Date:1/21/2017)... ... January 21, 2017 , ... Santa Rosa Orthopaedics (SRO) ... located at 167 Lynch Creek Way. The Petaluma office features three comfortable patient ... and rehabilitation services and on-site x-ray services. Two multi-specialist orthopaedic surgeons Dr. ...
(Date:1/20/2017)... ... , ... A new partnership between Goodwill® and Roadie, Inc. aims to make ... clothes to couches to dressers and bicycles. Roadie — the national on-the-way delivery network ... donation center through February 28th. , “January is an exciting time when resolutions ...
(Date:1/20/2017)... (PRWEB) , ... January 20, 2017 , ... Bionic Sports ... all walks of life, announced it had a successful January ECRM Trade Show in ... in the United States, which allows it to provide its products to all clients ...
(Date:1/20/2017)... ... January 20, 2017 , ... Michael and Betsy Brauser celebrated 5 years of ... the clinical trial has been life-saving as she has been on the trial ... Brauser was diagnosed with ovarian cancer in 2009. She underwent standard chemotherapy but a ...
Breaking Medicine News(10 mins):
(Date:1/21/2017)... Research and Markets has announced the addition of the "Advanced ... End User - Forecast to 2025" report to their offering. ... The Global Advanced ... around 7.8% over the next decade to reach approximately $330.70 billion ... markets for Advanced Drug Delivery across all the given segments on ...
(Date:1/20/2017)... 2017 Research and Markets has announced ... Devices, Implant Types, OTC Amplifiers, Diagnostic Instruments), Sales Volume, Company ... ... Hearing Aids Market Sales Volume, Company Analysis and Forecast to ... aid industry. The growing prevalence of hearing impairment ...
(Date:1/20/2017)... , Jan 20, 2017 Research and ... Testing Market Trends, Opportunities, and Future" report to their offering. ... This research ... emerging trends, and technologies, and provides a snapshot of the key ... 2015 and forecasts are provided from 2016 to 2020. The market ...
Breaking Medicine Technology: