Navigation Links
Implanting Electrodes in the Brain Could Help Treat Severe Depression

Implanting electrodes in the brain could help treat people who are suffering from severe depression, but do not succeed in responding to traditional treatment.

Thomas Schlaepfer, professor of psychiatry and psychotherapy at University Hospital in Bonn, Germany and associate professor of psychiatry and mental health at Johns Hopkins University School of Medicine in Baltimore, and his team are examining the prospects of deep brain stimulation, a therapy used to treat tremors associated with Parkinson's disease, to treat depression.

The idea behind the study is to rearrange disordered neural activity in the brain in a parallel way to how a person might reboot a computer to terminate a problem.

The system consists of a neurostimulator, a device about the size of a hockey puck that is rooted in the chest wall. Wires attached to the stimulator run under the skin to two electrodes that are put in through small holes in the skull and joined to the bone.

The stimulator, which can be operated by the patient, carries electrical current to the electrodes. Depending on its force and frequency, the current controls brain activity in a specific area.

Because a significant symptom of major depression is anhedonia, the inability to find delight from activities formerly experienced as delightful, Schlaepfer's group concentrated on the brain's reward center, a region called the nucleus accumbens, which responds to stimuli from such things as food, sex, and some drugs.

During their most recent study, the researchers surgically implanted the system into three individuals who experienced major depression and who had not responded to other treatments, including drugs of electroconvulsive therapy.

All the patients reported that they sensed no sensations when the stimulator was turned on. They also reported that they felt no changes in their condition after the stimulator was turned on. Yet al l of them almost instinctively began preparing for pleasurable activities.

Focusing on the accumbens region of the brain not only seems right from a theoretical standpoint but also from an experimental point of view because it could be one node in a larger circuit that affects depression, said Helen Mayberg, professor of psychiatry and neurology at Emory University School of Medicine in Atlanta.

But experts claim that focusing on the brain's pleasure centre could also have some unpleasant consequences.

"The nucleus accumbens has been modeled as an area of craving. Could you get habituated to the chronic stimulation? Sometimes side effects are worse than your primary symptoms, the Discovery News quoted Mayberg, as saying.

Still, Mayberg added that an in-depth understanding about how the brain functions will lead to better treatments.

"If there's buy-in scientifically and conceptually to the idea of a circuit and that some nodes are more important than others, the engineers will advance the technology," Mayberg said.


'"/>




Related medicine news :

1. Radical Idea of Implanting Tiny Electrodes to the Deaf
2. Use of Cellular Phones associated with Increased risk of Brain Tumors
3. Brain death – How to cope with it
4. “Brain fingerprinting”- The new lie detectr
5. Nasal Spray Could Take Drugs Direct to Brain.
6. Virus Combats Brain Tumour
7. Nasal Spray Could Take Drugs Directly to Brain
8. Control of anger disorder connected to Brain Dysfunction
9. High Levels of Protein Linked to Brain Shrinkage
10. Brain damage affects artistic skill
11. Brain cells protected by new compounds
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/27/2016)... ... June 27, 2016 , ... ... only authorized OSHA Training Institute Education Center headquartered in Northern California, has issued ... from extreme heat at their worksites. Employers with workers exposed to high ...
(Date:6/27/2016)... ... ... "FCPX editors can now reveal their media with growing colorful split screen ... - CEO of Pixel Film Studios. , ProSlice Color brings the split screens ... reveal the media of their split screens with growing colorful panels. , ProSlice Color ...
(Date:6/27/2016)... (PRWEB) , ... June 27, 2016 , ... ... for mental health professionals, announced today its affiliation with Tennessee Counseling Association. ... solutions to the network of the Tennessee Counseling Association, adding exclusive benefits and ...
(Date:6/27/2016)... ... June 27, 2016 , ... ePAY ... partnership with Connance, a healthcare industry leader providing predictive analytics to optimize ... combine to provide health systems, hospitals and ambulatory surgical centers with dramatic ...
(Date:6/27/2016)... ... June 27, 2016 , ... A ... revolutionize the emergency ambulance transport experience for the millions of people who require ... has disrupted the taxi industry through the use of technology. Now, SmartEMS has ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... 26, 2016 One of Australia,s ... formation of a new biotechnology company, Noxopharm Limited [ABN 50 608 ... IPO and to list on the ASX. Noxopharm is ... to enter a Phase 1 clinical study later this year. ... one of the biggest problems facing cancer patients - the ability ...
(Date:6/26/2016)... Jazz Pharmaceuticals plc (Nasdaq: JAZZ ... Antitrust Improvements Act of 1976, as amended ("HSR"), with ... ("Celator"; Nasdaq: CPXX ) expired effective June ... As previously announced on May 31, 2016, Jazz ... under which Jazz Pharmaceuticals has commenced a tender offer ...
(Date:6/26/2016)... June 27, 2016  VMS Rehab Systems, Inc. ( ... take whatever measures required to build a strong and ... is currently listed on the OTC Markets-pink current trading ... and CEO, "We are seeing an anomaly in market ... not only by the Company, but shareholders and market ...
Breaking Medicine Technology: