Navigation Links
Immunity carefully enhanced in elders by high-dose flu vaccines

High dose influenza vaccine not only provides protection against flu to the elderly people,// but also safely raises the resistance in these susceptible people without any major harmful effect. This was published in the May 22 issue of Archives of Internal Medicine, a JAMA/Archives journal.

Vaccines containing inactivated influenza virus have been available for 50 years to prevent flu and its complications, according to background information in the article. Immune responses decrease with age, however, and currently available flu vaccines are not always effective in the elderly. Recommended vaccines contain 15 micrograms (?g) of inactivated virus per strain.

Wendy A. Keitel, M.D., Baylor College of Medicine, Houston, and colleagues studied the response to vaccines containing 15, 30 and 60 ?g of virus among 202 individuals age 65 years and older (average age 72.4) in 2002. The 60-?g level was selected as the highest dosage because manufacturers would reasonably be able to produce that type of vaccine. Participants were randomly assigned to receive one of the three vaccines or a placebo injection and then were monitored daily for one week afterward. They were also examined 30 minutes, two days and 28 days after the vaccine and were contacted six months later to inquire about serious adverse events or side effects. Blood was drawn before the immunization and one month after.

On average, individuals who received higher dosages of vaccine had higher concentrations of antibodies against the flu virus in their blood one month later. In addition, a larger percentage of those who received the higher-dose vaccines had what physicians believe is a sufficient immune response to protect them from developing the flu if they were exposed to the virus. All three vaccine dosage levels were safe and well tolerated, according to the researchers. Although discomfort, redness or swelling at the site of the injection was more common among those who received t he 60 ?g dose than among those who received the 15 ?g dose, most reactions to the immunization were mild.

Although current vaccines are sufficient to protect younger adults from influenza, the elderly and others at high risk of hospitalization and death from the disease have not responded consistently, the authors write. “Improved vaccines are needed to reduce the morbidity and mortality associated with influenza in these vulnerable populations,” they write. “Increasing the dose of inactivated influenza vaccine consistently and safely increases the immunogenicity [immune response] of inactivated influenza virus vaccines; moreover, vaccines that contain higher doses have conferred significantly enhanced protection against naturally occurring influenza.”

Source: Newswie

Related medicine news :

1. CCR5 Mutation Confers Immunity Against HIV But Not Against West Nile Virus Illness
2. Strengthen Your Childs Immunity Give Him A Cat
3. Protected Environment v/s Unprotected Affect Hygiene Health Immunity
4. Long Term Exposure to Lab Animals Increases Immunity against Asthma
5. Waxing And Waning Of Dengue Epidemics Attributed To Cross-Immunity
6. Natural Immunity Against Avian Flu may Be Possible
7. Immunity May Be Weakened By Insecure Feeling
8. Zinc Supplements Enhance Immunity in Children
9. Sex life enhanced by cycling
10. Combined modality approach for effective treatment and enhanced survival in bile duct cancer
11. Incidence of iron deficiency reduced by nutrient enhanced cereal- rice
Post Your Comments:

(Date:11/26/2015)... Omaha, NE (PRWEB) , ... November 26, 2015 , ... ... careers searched by healthcare professionals and offered by healthcare staffing agency Aureus Medical ... top during the month of October 2015 among those searching for healthcare jobs through ...
(Date:11/26/2015)... CA (PRWEB) , ... November 26, 2015 , ... ... a new set of retro-fused, self-animating trailer titles with ProTrailer: Vintage. This newly ... options. These classically-influenced trailer titles work with any font, giving users limitless opportunities ...
(Date:11/25/2015)... ... 25, 2015 , ... Additional breast cancers found with MRI ... to a study published online in the journal Radiology. Researchers said that in ... a change in treatment. , Breast MRI is the most sensitive technique for ...
(Date:11/25/2015)... ... November 25, 2015 , ... Finnleo, a leader in the traditional and far-infrared ... traditional and far-infrared saunas. , For traditional saunas, Finnleo is offering ... sauna wood, and Finnleo uses only European Grade A Nordic White Spruce from sustainably ...
(Date:11/25/2015)... ... 2015 , ... Dr. John Pierce, Medical Director at the Ageless Forever clinic ... the Capillus272™ Pro laser therapy cap. FDA cleared for safety and efficacy, the Capillus272 ... need for surgery, prescription pills, or topical foams. , “Capillus272™ Pro is a ...
Breaking Medicine News(10 mins):
(Date:11/25/2015)... Nov. 26, 2015  The total global healthcare industry is ... 2015-2016. Latin America has the highest ... (excluding Japan ), is second with growth ... to face increased healthcare expenditure. In 2013-2014, total government funded ... 43.5% in 2008-2009 to 41.2% in 2013-2014. In real terms, ...
(Date:11/25/2015)... Nov. 25, 2015  The American Academy of ... (ACOG), and the March of Dimes cheered today,s ... Our Infants Act of 2015 (S.799), which ... newborns born exposed to drugs, such as opioids, ... introduction, all three organizations have worked together leading ...
(Date:11/25/2015)... Nov. 25, 2015 AAIPharma Services Corp./Cambridge ... of at least $15.8  Million to expand its ... NC . The expansion will provide additional ... the growing demands of the pharmaceutical and biotechnology ... expansion will provide up to 40,000 square feet ...
Breaking Medicine Technology: