Navigation Links
Immunity carefully enhanced in elders by high-dose flu vaccines

High dose influenza vaccine not only provides protection against flu to the elderly people,// but also safely raises the resistance in these susceptible people without any major harmful effect. This was published in the May 22 issue of Archives of Internal Medicine, a JAMA/Archives journal.

Vaccines containing inactivated influenza virus have been available for 50 years to prevent flu and its complications, according to background information in the article. Immune responses decrease with age, however, and currently available flu vaccines are not always effective in the elderly. Recommended vaccines contain 15 micrograms (?g) of inactivated virus per strain.

Wendy A. Keitel, M.D., Baylor College of Medicine, Houston, and colleagues studied the response to vaccines containing 15, 30 and 60 ?g of virus among 202 individuals age 65 years and older (average age 72.4) in 2002. The 60-?g level was selected as the highest dosage because manufacturers would reasonably be able to produce that type of vaccine. Participants were randomly assigned to receive one of the three vaccines or a placebo injection and then were monitored daily for one week afterward. They were also examined 30 minutes, two days and 28 days after the vaccine and were contacted six months later to inquire about serious adverse events or side effects. Blood was drawn before the immunization and one month after.

On average, individuals who received higher dosages of vaccine had higher concentrations of antibodies against the flu virus in their blood one month later. In addition, a larger percentage of those who received the higher-dose vaccines had what physicians believe is a sufficient immune response to protect them from developing the flu if they were exposed to the virus. All three vaccine dosage levels were safe and well tolerated, according to the researchers. Although discomfort, redness or swelling at the site of the injection was more common among those who received t he 60 ?g dose than among those who received the 15 ?g dose, most reactions to the immunization were mild.

Although current vaccines are sufficient to protect younger adults from influenza, the elderly and others at high risk of hospitalization and death from the disease have not responded consistently, the authors write. “Improved vaccines are needed to reduce the morbidity and mortality associated with influenza in these vulnerable populations,” they write. “Increasing the dose of inactivated influenza vaccine consistently and safely increases the immunogenicity [immune response] of inactivated influenza virus vaccines; moreover, vaccines that contain higher doses have conferred significantly enhanced protection against naturally occurring influenza.”

Source: Newswie
'"/>




Related medicine news :

1. CCR5 Mutation Confers Immunity Against HIV But Not Against West Nile Virus Illness
2. Strengthen Your Childs Immunity Give Him A Cat
3. Protected Environment v/s Unprotected Affect Hygiene Health Immunity
4. Long Term Exposure to Lab Animals Increases Immunity against Asthma
5. Waxing And Waning Of Dengue Epidemics Attributed To Cross-Immunity
6. Natural Immunity Against Avian Flu may Be Possible
7. Immunity May Be Weakened By Insecure Feeling
8. Zinc Supplements Enhance Immunity in Children
9. Sex life enhanced by cycling
10. Combined modality approach for effective treatment and enhanced survival in bile duct cancer
11. Incidence of iron deficiency reduced by nutrient enhanced cereal- rice
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/26/2017)... (PRWEB) , ... May 26, 2017 , ... Mediaplanet is ... Wound Care" campaign in USA Today, which will educate readers on how to take ... the campaign, a large focus is placed on melanoma. Dancing with the Stars professional, ...
(Date:5/26/2017)... Clara, Calif. (PRWEB) , ... May 26, 2017 ... ... announces the integration of the CareFusion NOX-T3 portable sleep monitor with its Somnoware ... provides a consistent, browser-based interface for diagnostic device operations. With this platform, initializing ...
(Date:5/26/2017)... , ... May 26, 2017 , ... After raising nearly ... Top gadget will continue to be available at a discounted crowdfunding price on ... stress wherever they are, I also wanted to bring a fidget toy to the ...
(Date:5/26/2017)... , ... May 26, 2017 , ... “When the Stars ... Home” is the creation of published author Laura Weigel Douglas, an avid reader who ... in a house that sometimes feels like Green Hills Adventure Camp. She couldn’t be ...
(Date:5/26/2017)... ... , ... Water damage to the flooring of several classrooms at The Fort ... with a number of critical issues to address before students could return to classes. ... little or no disruption to class schedules. Second, the project had to comply with ...
Breaking Medicine News(10 mins):
(Date:5/11/2017)... 11, 2017  Thornhill Research Inc. ( ... an $8,049,024 USD five-year, firm-fixed-priced, indefinite-quantity/indefinite-delivery contract by ... Commercial Corporation (CCC) ( Ottawa, Ontario, Canada ... administer general anesthesia to patients requiring emergency medical ... US Marine Corps have been a longtime partner ...
(Date:5/10/2017)... , May 10, 2017 Radiology has become ... its costs have also spiraled to the number one ... to radiology than ever before as the most complete ... a patient with lower back pain an MRI may ... reason for pain, resulting in entirely different treatment protocols.  ...
(Date:5/9/2017)... , May 9, 2017  Oramed Pharmaceuticals Inc. ... a clinical-stage pharmaceutical company focused on the development ... the Canadian Intellectual Property Office has granted Oramed ... Administration of Exenatide". The patent covers Oramed,s invention ... GLP-1 is an incretin hormone that stimulates ...
Breaking Medicine Technology: