Navigation Links
Immune cells halt round in space

An immune cell swallows a small capsule-shaped bacteria. The immune cells which help protect us from disease does not generally work the way they should in space travellers and it could be something to do with their shape. Researchers at NASA's Johnson Space Center (JSC) have been studying how immune cells behave in microgravity as part of their research on the health effects of space on astronauts.//

It has been found that astronauts have elevated virus levels their sneezes contain up to ten times more Epstein-Barr virus than normal Earth sneezes, for example. Looking at the key immune cells, researchers have found that B-cells, which produce antibodies to flag invading micro-organisms for destruction, and T-cells which actually physically attack them, have both been found to behave differently in space.

In space, T-cells do not multiply properly, neither move or signal each other as well and overall seem less able to destroy invaders. While one possibility is that the unique physical and psychological stresses of space flight might trigger immune-altering hormones, another possibility is that the weightlessness of space might be affecting the immune cells directly. To investigate this, NASA has developed a "rotating bioreactor" which allows researchers to investigate the possible effects of microgravity on individual immune cells without the complications of hormone effects.

The bioreactor consists of a rotating container full of a fluid which allows cells to remain suspended for months at a time in continual free fall, just as they would be in Earth orbit. According to Neal Pellis, chief of JSC's Biological systems Office, the cells in the bioreactor began to change in the first 15 minutes. One of the first changes was that T-cells were somehow forced to remain round and the researchers believe this could be responsible for the problems seen.

On Earth, T-cells can change their shape, protruding portions of themselves s o they can move around like amoebas. T-cells need to move in order to get to sites of infections, tumors and immune system organs. The changed shape could also make it harder for cells to communicate as their ability to interact is reduced by the rigid round shape. Researchers do not understand why the T-cells stay round in microgravity but suggest that intermolecular or submolecular forces such as hydrogen bonding might play a larger role in determining the cell's shape in the absence of Earth's gravity.

They say finding out is important to both astronauts and people on Earth since understanding the way physical forces affect T-cells could eventually enable scientists to control them. "There are times when we don't want them to invade - transplants, for example. And there are cases when we want them to act vigorously, like in tumors," said Pellis.


'"/>




Related medicine news :

1. Immune function could benefit from exercise
2. Reviving the Immune System
3. Wrestling found To Be Good for the Immune System
4. Immune Boost With LHRH To Help Cancer And Transplant Patients
5. Researchers Find Out The Cause Of Immune Attacks Behind Hearing Loss
6. Block Immune System Chemical For Treating Asthma
7. Immune Response Of Human Beings Can Be Re-energized
8. Weizmann Institute of Science says Immune Cells Could Help Maintain Brain Function
9. Antidepressant drugs interacts with Immune cells
10. Specific Immune Mechanism against DNA viruses
11. Immune response in Occupational metal fume inhaling workers
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... Dickinson ... offers insurance and financial preparation services, is providing an update on a charitable ... , Rock City Rescue is a locally recognized nonprofit that provides shelter and ...
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... ... established the certification process to promote standards of excellence for the field of ... scheduled for March 22 – 25, 2018 in Orlando, Florida at the Omni ...
(Date:10/13/2017)... ... , ... Apple Rehab Shelton Lakes , which specializes in the delivery ... as part of a disaster drill on October 3rd. , Apple Rehab participated with ... Manager, as well as the Connecticut Long Term Care Mutual Aid Plan (LTC-MAP). ...
(Date:10/13/2017)... ... October 13, 2017 , ... Global Healthcare Management’s 4th Annual Kids Fun ... NJ. This free event, sponsored by Global Healthcare Management’s CEO, Jon Letko, is ... is geared towards children of all ages; it is a non-competitive, non-timed event, which ...
(Date:10/13/2017)... ... 2017 , ... “The Journey: From the Mountains to the Mission Field”: the ... in the Philippines. “The Journey: From the Mountains to the Mission Field” is the ... She has taught all ages and currently teaches a class of ladies at her ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)...  True Health, a leader in integrated diagnostics ... National Breast Cancer Awareness month to educate doctors ... Research recently published in ... than 10 million American women are at significant ... BRCA2 and have not had testing. These mutations can ...
(Date:10/5/2017)... Oct. 5, 2017  In response to the ... and Maxillofacial Surgeons (AAOMS) released prescribing recommendations that ... be used as a first-line therapy to manage ... Recognizing the value and ... Paper "Opioid Prescribing: Acute and Postoperative Pain Management" ...
(Date:10/2/2017)... -- Eli Lilly and Company (NYSE: LLY ) ... of 2017 on Tuesday, October 24, 2017. Lilly will ... the investment community and media to further detail the ... begin at 9 a.m. Eastern time. Investors, media and ... the conference call through a link that will be ...
Breaking Medicine Technology: