Navigation Links
Immune System Protein Could Be the Key Infertility

develop in the testes and undergo a series of changes until they are mature and viable.

They begin life as round cells and as they mature they elongate and develop a tail.

Defects at any stage of this process can prevent the cells from maturing and lead to male infertility.

The team knocked out the function of the gene that controls production of JAM-C in mice.

They found that the male mice unable to produce JAM-C were infertile and had round instead of elongated sperm cells.

The team said the molecule was widely distributed in round sperm cells but could be found at a particularly high level on one side of the cell.

As the cells matured JAM-C was only found in the heads of elongated sperm.

The findings led the team to believe that JAM-C might have a role in defining which end of the sperm cell becomes the head.

To explore this further they studied the cellular distribution of molecules known to regulate the process.

They found that these molecules were distributed in the same areas as JAM-C during sperm development.

Lead researcher Dr Ralf Adams said: "We found that JAM-C is essential for sperm cells to mature in mice. Our results suggest that the molecule is key in determining which end becomes the head and which the tail in sperm cells."

To see if JAM-C played a similar role in human sperm, they studied its distribution in human testes.

They found a pattern that was strikingly similar to the one found in mice.

Dr Adams said: "We discovered JAM-C had a similar pattern of expression in human sperm to that found in mice. This suggests that defects in JAM-C could contribute to male infertility in humans. It will be important for scientists working in this area to investigate this further."




'"/>




Page: 1 2

Related medicine news :

1. Immune cells halt round in space
2. Immune function could benefit from exercise
3. Reviving the Immune System
4. Wrestling found To Be Good for the Immune System
5. Immune Boost With LHRH To Help Cancer And Transplant Patients
6. Researchers Find Out The Cause Of Immune Attacks Behind Hearing Loss
7. Block Immune System Chemical For Treating Asthma
8. Immune Response Of Human Beings Can Be Re-energized
9. Weizmann Institute of Science says Immune Cells Could Help Maintain Brain Function
10. Antidepressant drugs interacts with Immune cells
11. Specific Immune Mechanism against DNA viruses
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Immune System Protein Could the Key Infertility

(Date:11/26/2014)... 2014 Loffler Companies has been selected ... Imaging, an online information and news publication for resellers ... sixth consecutive year Loffler has earned this prestigious award ... Elite Dealer Awards honor the best and the brightest ... Dealer honorees were chosen for their innovative marketing and ...
(Date:11/26/2014)... Senior Planning Services, providing “expert guidance ... organization providing the adult demographic education and access ... navigate the rough seas of applying for Medicaid. Part ... the topic of Medicaid eligibility and proper planning, while ... applying for this coverage. , Senior Planning Services ...
(Date:11/26/2014)... Call 866-997-4948 (Us-Canada Toll Free) Tel: +1-518-618-1030 with ... sales(at)researchmoz(dot)us , Researchmoz.us announces a new research report ... deep study of the report on the diabetes topic ... The global glucose monitoring market has a growth rate ... diabetics in the world. Their numbers have prompted the ...
(Date:11/26/2014)... 2014 Louisiana Back Institute, leaders ... in minimally invasive spine surgery, announces today the ... rapidly growing provider network of orthopedic spine surgeons ... with the network’s continuing success providing the most ... residents who are suffering from orthopedic spine conditions ...
(Date:11/26/2014)... who enter puberty early are at increased risk for ... linked with a number of factors associated with depression, ... to the researchers. Early puberty was also linked to ... and having friends who were prone to getting into ... an association between early puberty and these factors, it,s ...
Breaking Medicine News(10 mins):Health News:Loffler Companies Recognized as an Elite Dealer for Sixth Consecutive Year 2Health News:Senior Planning Services Teams Up with SeniorNet To Educate Seniors On Medicaid Planning 2Health News:Latest Report on Diabetes Market 2014 - Global Market Size, Share, Trends and Forecast by Researchmoz.us 2Health News:Latest Report on Diabetes Market 2014 - Global Market Size, Share, Trends and Forecast by Researchmoz.us 3Health News:Louisiana Back Institute Welcomes Dr. K. Samer Shamieh into Medical Provider Network 2Health News:Early Puberty Linked to Increased Risk of Depression in Teens 2
... 2 BlueCross BlueShield of South Carolina announced today ... will be held during lunchtime hours on Wednesday, April ... country, as well as other employers, will encourage their ... and participate in a 30-minute lunchtime walk. The goal ...
... Accelerated Community Oncology Research Network (ACORN(TM)), an ... of its annual Principal Investigators, Meeting held in ... community-based oncology practices throughout the United States met ... treatment trends, as well as promising new molecules ...
... National Product Launch to Include 24-oz and Convenient ... PURE Bioscience (Nasdaq: PURE ) ... the distribution of PURE,s silver dihydrogen citrate (SDC)-based ... in Sterifide Laboratories, OneShot Plus product line. ...
... first Eklin RapidStudy(TM),digital radiography (DR) system in Adams ... Clinic which serves south central Pennsylvania,including Gettysburg, Fairfield ... Systems, the leader in veterinary care DR and ... patients,supporting the Clinic,s commitment to excellent patient care. ...
... SynCare, LLC, announces the extension of its contract with ... MHS, a Medicaid Managed Care Company, serving SCHIP and ... the company in providing comprehensive care and support services ... continuing our partnership with SynCare for prenatal care coordination ...
... and vegetarians most affected, study says , , MONDAY, March 2 (HealthDay ... their blood before and after conception have a greater chance of ... study says. , Most at risk may be vegans ... animal-based foods, noted an American and Irish research team whose findings ...
Cached Medicine News:Health News:S.C. BlueCross to Celebrate Third Annual National Walk @ Lunch Day With Community Events in Columbia, Charleston, Greenville 2Health News:ACORN's Success in Delivering Top Quality Research Portfolio to Community-Based Oncology Practices Presented at Annual Investigator Meeting 2Health News:ACORN's Success in Delivering Top Quality Research Portfolio to Community-Based Oncology Practices Presented at Annual Investigator Meeting 3Health News:Sterifide Laboratories to Launch 'Powered by SDC' OneShot Plus Disinfectant and Deodorizer 2Health News:Sterifide Laboratories to Launch 'Powered by SDC' OneShot Plus Disinfectant and Deodorizer 3Health News:Sterifide Laboratories to Launch 'Powered by SDC' OneShot Plus Disinfectant and Deodorizer 4Health News:Dr. Flake's Animal Wellness Clinic Installs Adams County's First Eklin Digital Radiography System 2Health News:Dr. Flake's Animal Wellness Clinic Installs Adams County's First Eklin Digital Radiography System 3Health News:SynCare Receives Managed Health Services Contract Renewal 2Health News:B12 Deficit May Boost Risk of Birth Defects 2
(Date:11/26/2014)... 26, 2014 The medical magnetic resonance ... of 4%, with world market revenues for 2013 ... and other types of medical imaging have led ... numerous medical conditions in children and adults, each ... report, Medical Imaging Markets , analyzes the ...
(Date:11/26/2014)...  At the American Dental Association,s Annual Meeting in ... Kerr Group was honored to be part of the ... to see and test the Best of Class winners ... on the latest developments in dental technology. This year, ... CariVu Caries Detection Device and Kerr Demi ™  ...
(Date:11/26/2014)...  Medtronic,s roughly $43 billion acquisition and ... in the media for its US Federal tax ... player in one of the fastest growing device ... research firm said  the two companies compete in ... of solutions spanning inpatient to home care, and ...
Breaking Medicine Technology:Kalorama: Steady Growth in the Medical MRI Market 2Kalorama: Steady Growth in the Medical MRI Market 3KaVo Kerr Group Showcased in Pride Institute Technology Expo at ADA Annual Meeting 2KaVo Kerr Group Showcased in Pride Institute Technology Expo at ADA Annual Meeting 3Medtronic - Covidien: Beyond Taxes, Deal Will Create Patient Monitoring Power, according to Kalorama Information 2Medtronic - Covidien: Beyond Taxes, Deal Will Create Patient Monitoring Power, according to Kalorama Information 3
... CMC Biologics today announced the execution of ... Sankyo,) to provide process development support and manufacture ... The two companies have recently begun work on ... manufacturing facility. Specific terms of the agreement were ...
... /PRNewswire-Asia/ -- Global Pharm Holdings Group, Inc. ... a China-based, growing vertically integrated pharmaceutical company ... Medicine ("TCM") herbs cultivation and processing business ... and Shandong provinces, today announced that it ...
Cached Medicine Technology:CMC Biologics Announces Agreement With Daiichi Sankyo Company to Develop and Manufacture Antibodies 2Global Pharm Announces the Closing of US$15 Million Redeemable Convertible Bonds Financing 2Global Pharm Announces the Closing of US$15 Million Redeemable Convertible Bonds Financing 3