Navigation Links
Immune Cells Destroy Bone In Gum Disease

Immune cells play a big role in the bone loss that results due to periodontal or gum disease, according to researchers at The Forsyth Institute. Earlier researchers had// speculated that the immune system was involved in destruction of bone in periodontal disease, but this is the first time it has been confirmed in human gum tissue. Forsyth researchers hope that the finding would help create new ways to stop bone loss in gum disease.

The study, led by Toshihisa Kawai, D.D.S., Ph.D., examined whether immune response to periodontal bacteria is protective or pathogenic in the context of gum disease. Periodontal disease is an infection of the teeth, and their supporting structures, which results in soft tissue and bone destruction, leading to tooth loss. Dr. Kawai and his colleagues had found that B cells (B and T lymphocytes are immune cells) can contribute to increased periodontal bone loss coordinating with activated T-cells. Both cell types had previously been found to manifest a host immune response to the bacteria causing bone loss in animal models, by his group.

"This research validates our hypothesis that immune cells are harmful in gum disease," said Dr. Kawai. "It's a groundbreaking discovery because it truly gives a new understanding of periodontal disease, while also raising interesting questions about immune cells. We hope this work will help us save people's teeth in the future."

Research Overview

RANKL is a protein that is a major factor in the regulation of osteoclasts (cells that destroy bone). Dr. Kawai's research examined the receptor activator of NF-kB ligand, (RANKL)-mediated osteoclastogeneis, and the pivotal role it plays in inflammatory bone resorption. The aim of this study, which will be published in the September issue of the American Journal of Pathology, was to identify the cellular source of RANKL in the bone resorptive lesions of periodontal disease. An active periodontal lesion is characterize
'"/>




Page: 1 2

Related medicine news :

1. Immune cells halt round in space
2. Immune function could benefit from exercise
3. Reviving the Immune System
4. Wrestling found To Be Good for the Immune System
5. Immune Boost With LHRH To Help Cancer And Transplant Patients
6. Researchers Find Out The Cause Of Immune Attacks Behind Hearing Loss
7. Block Immune System Chemical For Treating Asthma
8. Immune Response Of Human Beings Can Be Re-energized
9. Weizmann Institute of Science says Immune Cells Could Help Maintain Brain Function
10. Antidepressant drugs interacts with Immune cells
11. Specific Immune Mechanism against DNA viruses
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Immune Cells Destroy Bone Gum Disease

(Date:4/19/2015)... has released a new blog post explaining what motorcycles ... plan . , Motorcycles can be difficult to ... auto insurance plans. Insurance brokers have gathered a list ... cheaper to insure. , The budget that a ... auto insurance plan that he/she will buy. When comparing ...
(Date:4/19/2015)... has released a new blog post explaining that ... family members. , Accidental death and dismemberment insurance ... in an accident. The policy will cover car accidents ... plan. However, AD&D insurance can also be an independent ... The newly blog post presents the advantages of owning ...
(Date:4/19/2015)... Fla. (PRWEB) April 19, 2015 The ... DO, MPH, MHCM, FACS, as the inaugural winner of ... at its annual meeting, April 18, in Las Vegas, ... Medical Group, vice chairman of the department of surgery ... and Medical Center in Hartford, Connecticut, was instrumental in ...
(Date:4/19/2015)... April 19, 2015 Broccoli sprout extract ... in a small group of healthy human volunteers, the ... with UPMC CancerCenter , announced today at the ... Meeting in Philadelphia. , The promising results will ... will recruit participants at high risk for head and ...
(Date:4/19/2015)... Carinsurancehints.com has released a new blog post providing a ... insurance benefits . , Drivers who were involved in ... information for claiming auto insurance benefits. Exchanging insurance information is ... most of the damages. The newly released blog post explains ... , Drivers can compare online rates and find the best ...
Breaking Medicine News(10 mins):Health News:Buying Auto Insurance for Motorcycles - Models That Are Cheap to Cover! 2Health News:Accidental Death and Dismemberment Insurance Can Provide Financial Security! 2Health News:Dr. Scott Ellner named inaugural Roger Schenke Award winner 2Health News:Dr. Scott Ellner named inaugural Roger Schenke Award winner 3Health News:Preventing Cancer with Broccoli Sprout Extract 2Health News:Preventing Cancer with Broccoli Sprout Extract 3Health News:An Online Guide About Claiming Auto Insurance Benefits After an Accident 2
... properties of bacteria to form barrier against illness , , ... Polytechnic Institute say that have solved the mystery of ... study, published in the current issue of Colloids ... the thermodynamic properties of bacteria in the urinary tract ...
... National Institutes of Health has awarded $128 million to ... Jeffrey Krischer, PhD, to coordinate worldwide studies on the ... a seven-year award, supports Dr. Krischer,s coordination of the ... , The award adds to the $169 million received ...
... Masimo provides Aurora with technology and sensor standardization ... its facilities - creating efficiencies and cost savings, ... inventor,of Pulse CO-Oximetry and Measure-Through-Motion-and-Low-Perfusion Pulse,Oximetry, announced that ... Masimo SET pulse oximetry technology. The integrated health,care ...
... As tens of thousands of Americans,prepare to attend the ... injury or illness -- and how to deal with ... adequate, appropriate medical care in foreign lands can be,daunting, ... themselves,peace of mind," said Angelo Masciantonio, CEO and co-founder ...
... 31 /Xinhua-PRNewswire/ -- Chindex International,Inc. (Nasdaq: CHDX ... products and services in the People,s Republic of ... fiscal 2009 first quarter,financial results on Thursday, August ... a conference call at 8:00 am ET that ...
... Feat could one day lead to tailor-made cells to treat ... -- Scientists have turned skin cells from patients with Lou ... the patients, own neurons. , An unlimited number of these ... a capability which should result in a better understanding of ...
Cached Medicine News:Health News:Study Explains How Cranberries Prevent Urinary Infections 2Health News:University of South Florida receives new multimillion award to assess juvenile diabetes treatments 2Health News:University of South Florida receives new multimillion award to assess juvenile diabetes treatments 3Health News:Aurora Health Care Completes System-Wide Conversion to Masimo SET Pulse Oximetry Technology 2Health News:Aurora Health Care Completes System-Wide Conversion to Masimo SET Pulse Oximetry Technology 3Health News:Aurora Health Care Completes System-Wide Conversion to Masimo SET Pulse Oximetry Technology 4Health News:Aurora Health Care Completes System-Wide Conversion to Masimo SET Pulse Oximetry Technology 5Health News:Americans Attending Beijing Olympics Should Plan Ahead for Medical Emergencies 2Health News:Chindex International to Report Fiscal 2009 First Quarter Financial Results 2Health News:Chindex International to Report Fiscal 2009 First Quarter Financial Results 3Health News:Scientists Turn Skin Cells Into Motor Neurons in ALS Patients 2Health News:Scientists Turn Skin Cells Into Motor Neurons in ALS Patients 3
(Date:4/19/2015)... , April 19, 2015  Blueprint Medicines today ... candidate BLU-285 has significant anti-tumor activity in treatment-resistant ... and maintained complete tumor regression in all mice ... were presented at the American Association for Cancer ... advances in treating GIST, there are still subsets ...
(Date:4/17/2015)... /CNW/ - The issue: In ... one lot (lot 710535) of Clavulin-400 (70mL) after receiving a ... found in one bottle of the  product. No other lots ... Clavulin-400 is an oral antibiotic used in adults and ... infections. Clavulin-400 comes as a powder in bottles and is ...
(Date:4/17/2015)... Contego Medical, the first and only ... for angioplasty balloon and stent delivery catheters, announces ... financing round led by Hatteras Venture Partners, an ... medical devices, biopharmaceuticals, diagnostics and related opportunities in ... Partners, Lookout Capital and Medical Mutual. ...
Breaking Medicine Technology:Blueprint Medicines Presents New Preclinical Data Demonstrating Significant Anti-Tumor Activity of BLU-285 in Treatment-Resistant GIST and on Novel Cancer Drug Targets 2Blueprint Medicines Presents New Preclinical Data Demonstrating Significant Anti-Tumor Activity of BLU-285 in Treatment-Resistant GIST and on Novel Cancer Drug Targets 3Blueprint Medicines Presents New Preclinical Data Demonstrating Significant Anti-Tumor Activity of BLU-285 in Treatment-Resistant GIST and on Novel Cancer Drug Targets 4Advisory - Clavulin-400 liquid oral antibiotic: One lot recalled after glass pieces found in one bottle 2Contego Medical Closes $5.6 Million in Series B Funding 2Contego Medical Closes $5.6 Million in Series B Funding 3
... ANGELES, March 3, 2011 InstaCare Corp. (OTC Bulletin ... prescription drugs, home testing products for the chronically ill, ... programs, and a leading developer of revolutionary patent pending ... today announced that it has migrated its recently patent ...
... Virtual Radiologic (vRad), a technology-enabled national ... Central Illinois-based radiology practice serving Champaign/Urbana, Effingham, ... of a strategic alliance, merging Lakeland with ... practice will be called Lakeland Radiology Alliance, ...
Cached Medicine Technology:InstaCare Extends MD@Hand & MD@Work Mobile EMR/EHR Technology to Smart Pad Systems 2InstaCare Extends MD@Hand & MD@Work Mobile EMR/EHR Technology to Smart Pad Systems 3Virtual Radiologic and Lakeland Radiologists Partner to Create Lakeland Radiology Alliance 2Virtual Radiologic and Lakeland Radiologists Partner to Create Lakeland Radiology Alliance 3
Inquire...
The Spex SkinSkan is the only in-vivo, fibre-optic spectrofluorometer designed specifically for skin-fluorescence measurements. It is also ideal for many remote sensing steady-state fluorescence appl...
The unique RF-1501 optical design provides exceptional sensitivity in an incredibly compact instrument....
... of DNA, RNA, Or Fluorescent Tags. Accurate quantitation ... critical to life science research. The RF-Mini 150 ... quantities as small as 1ng/ml of DNA specific ... excitation and emission filters, the RF-Mini 150 can ...
Medicine Products: