Navigation Links
Identifying bacteria made amiable

A Queensland group have developed an efficient method of identifying strains of bacteria, which will help to manage outbreaks of diseases such as meningococcal disease. The Cooperative Research Centre for Diagnostics, based at Queensland University of Technology (QUT) has taken advantage of two new technologies// that have emerged in the area of DNA sequencing recently - DNA chip technology and comparative gene sequence databases.

The Queensland team saw an opportunity. "All this comparative sequence data emerging at the same time as the emergence of the DNA chip technology meant that is was a superb opportunity to be able to make use of this explosion of data," said Dr Paul Giffard, a microbiologist and senior research fellow at the CRC for Diagnostics.

When DNA chip technology is combined with the vast amount of comparative gene sequences that are held on databases such as the Multi Locus Sequence Typing, there is a potential for fast, cheap bacteria strain identification.

DNA chips work in a similar way to microarrays. "It|s just a way of putting lots and lots of different bits of DNA onto a solid support and then subjecting that to some sort of reaction," explained Dr Giffard. They allow researchers to look at individual bases in a sample.

The group hypothesised that instead of doing sequencing to get a reliable genetic fingerprint, it was possible to 'mine' the data in multi-locus-sequence databases to find single bases or locations within genes - called single nucleotide polymorphisms - that are variable. Those bases or polymorphisms can then be interrogated using emerging DNA chip technology to obtain a genetic fingerprint.

The group focused on the meningococcal bacteria because it is a significant public health problem, and it is already routinely subjected to genetic fingerprinting by different methods by public authorities. It also happened to be the first multi-locus-sequence database put up on the web. There is an enormous amount of interest in tracking this organism.

When there is an outbreak of a disease like meningococcal disease, it is useful to know if people in different locations have been infected by the same strain or by two different strains coincidentally.

Comparative techniques that are currently being used for fingerprinting such as Pulse Field Gel Electrophoresis or Multi Locus Enzyme Electrophoresis have problems with replication between laboratories. The new system is not only fast, but highly replicable. While the team is currently looking at bacteria only, they anticipate extending the research to viruses in the future.


'"/>




Related medicine news :

1. Identifying brain lesions with impaired consciousness
2. Identifying Virus Found To Be Essential for HIV Patients
3. Identifying Those At Risk For Diabetes
4. Identifying Predictors Of Anthrax
5. Identifying The Risks Of Developing Schizophrenia
6. Identifying Irregular Heart Beats
7. Identifying Those At Risk For Diabetes
8. Identifying Heart Disease Early
9. Identifying The Risk For Kidney Infection
10. Identifying What Consumers Look For On Food Stuff Labels
11. Scientists Closer To Identifying Gene Connected To Alzheimers
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/20/2017)... ... June 20, 2017 , ... Dr. Manju ... OH for leading-edge care, whether or not they have a referral. Dr. Kejriwal ... WaterLase® iPlus™ laser, she targets bacteria and damaged tissue without affecting the surrounding ...
(Date:6/20/2017)... PA (PRWEB) , ... June 20, 2017 , ... ... at Allegheny Health Network’s (AHN) Jefferson Hospital is providing physicians with advanced capabilities ... scanner provides higher-resolution images than traditional MRIs, enabling doctors to get a more ...
(Date:6/20/2017)... ... June 20, 2017 , ... In ... Stevia Sweetener, Michael P. May, Ph.D., recently accepted the distinguished Sun Corridor Export ... selected Wisdom Natural Brands (WNB), and 16 other businesses from Pima, Pinal, and ...
(Date:6/20/2017)... , ... June 20, 2017 , ... ... agency, recently became re-accredited by the Joint Commission, which accredits and ... accreditation and certification is recognized nationwide as a symbol of quality that reflects ...
(Date:6/20/2017)... ... 20, 2017 , ... MEDI+SIGN, a healthcare technology company that ... Stanowski, DHA, FACHE to the MEDI+SIGN Advisory Board. , “We are eager ... provide invaluable direction for the company,” says Andrew Hoffman, President of MEDI+SIGN. ...
Breaking Medicine News(10 mins):
(Date:6/16/2017)... years ago today, the Monterey Pop Festival opened its gates ... Francisco "Summer of Love."  To celebrate the anniversary, Northern Light® ... market research portals that it will begin delivering to customers ... "Summer of Love (For Our Customers)."  ... Northern Light ...
(Date:6/14/2017)... June 14, 2017 The Bio Supply Management ... City of Fremont and the Biomedical Manufacturing ... industry in California by providing ... networking, and fostering workforce development. The primary focus of ... of start-ups, as well as small and mid-sized biomedical ...
(Date:6/13/2017)... Zimmer Biomet Holdings, Inc. (NYSE and SIX: ZBH), ... U.S. Food and Drug Administration (FDA) has notified the Company ... its Zhejiang, China manufacturing facility has ... successful clearance of the Warning Letter related to our ... measure of the progress we have made in our ongoing ...
Breaking Medicine Technology: