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IMP3 the Novel Biomarker for Metastatic Cancer

ically treated with systemic therapy. Systemic therapy, however, is associated with substantial toxicity and therefore is typically indicated only when a patient’s cancer has spread. With this paper, the researchers propose that IMP3 can be used at initial diagnosis, which would be the optimal time for considering early systemic therapy for those patients whose cancer has a high likelihood of metastasizing.

‘IMP3 testing is a simple, inexpensive and reliable assay that can be easily applied in routine clinical practice,’ explained Jiang. ‘If we can identify in those patients with early-stage disease the high potential to develop metastasis after surgery, we may be able to alter the course of therapy to improve outcomes and survival.’ Jiang and colleagues look forward to clinical studies to further evaluate the IMP3 testing in other cancers and the correlation to patient outcomes. The University of Massachusetts Medical School, one of the fastest growing academic health centers in the country, has built a reputation as a world-class research institution, consistently producing noteworthy advances in clinical and basic research. The Medical School attracts more than $174 million in research funding annually, 80 percent of which comes from federal funding sources.

Source: Newwise
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