Navigation Links
IMP3 the Novel Biomarker for Metastatic Cancer

tant metastasis of renal cell carcinomas is the primary cause of death for affected patients and the metastatic potential of these tumors is often unpredictable. There is a great need for biomarkers that can accurately distinguish those tumors with a high probability of metastasis. In an effort to identify biomarkers for renal cell carcinoma, Dr. Jiang and colleagues chose to study IMP3, a protein that was already demonstrated to be highly expressed in primary tumors from other cancers, including lung and pancreatic cancers. Examining the tissue samples and clinical information from 406 patients with primary renal cell carcinomas who underwent radical or partial kidney removal at three different medical centers, the scientists found that the expression of IMP3 was significantly increased in the metastatic renal cell carcinomas.

They further demonstrated this elevated expression of IMP3 in primary renal cell carcinomas can predict tumor metastasis. Their data shows that the expression of IMP3 was significantly increased not only in metastastic renal cell carcinomas but most importantly also in patients with primary renal cell cancers who developed metastatic disease as compared with renal cell cancers without metastasis. Remarkably, Jiang and collaborators found that 80 percent of patients with IMP3 positivity in their localized renal cell carcinoma developed metastasis, whereas only 13 percent of patients without expression of IMP3 in their primary tumors developed metastases.

Because patients whose tumors express IMP3 have a high potential to develop metastasis, IMP3 provides a marker that can help identify those patients who might benefit from a different follow-up approach after partial or complete kidney removal. Surgical removal of primary renal cell carcinoma can be a curative treatment when the disease is localized; however because distant metastasis remains the primary cause of therapeutic failure, patients with metastatic disease are typ
'"/>




Page: 1 2 3

Related medicine news :

1. Novel "CYCLOSPORINE CAPSULE FORMULATION" to be launched
2. Novel biopsy technique for prostate cancer
3. Novel computer model for breast cancer
4. Novel research on liver cancer
5. Novel way to fight cancer
6. Novel test for bowel cancer
7. Novel Anti-Neutrophilic Effect produced by Salmeterol in mild asthma patients
8. Novel Therapy for Chronic Problem
9. Blood Sugar Kept In Control By Novel Protein
10. Novel antibiotic dressing developed for improved wound healing
11. United Kingdom Is Lagging In Novelty In The Field Of Pharmaceuticals
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: IMP3 the Novel Biomarker for Metastatic Cancer

(Date:12/25/2014)... Product liability lawsuits filed in the ... http://www.consumerinjurylawyers.com/DePuy/ ) continue to move forward in federal court, ... in the U.S. District Court, Northern District of Ohio ... conference on January 7, 2015, at the Paul G. ... Palm Beach, Florida. The Conference is scheduled to begin ...
(Date:12/25/2014)... 26, 2014 Recently, Dylan Queen, a ... excitedly released its collection of discounted prom dresses, most ... a senior spokesman of the company, the promotion is ... promotion is to expand the UK market. , The ... different colors, lengths, and styles: A-line strapless, empire strapless ...
(Date:12/25/2014)... sells many bamboo products and the business is famous ... announces big discounts on its bamboo mats , which ... the world’s leader in bamboo flooring. According to the ... 2015. , The bamboo mats are made from well-treated ... the bamboo strips for the mats are boiled and ...
(Date:12/25/2014)... has updated its blog to provide professional shopping tips on wedding ... at LunaDress.co.uk come with big discounts, up to 80 percent off. ... out to be a most exciting memory and can show off ... to a wedding. On the updated fashion blog, ladies can now ... big day . , Going out with friends to a party ...
(Date:12/25/2014)... (HealthDay News) -- Overeating is common during the holidays, but ... an expert says. "Don,t arrive at a party hungry. ... know you,ll be attending a party, but deprivation leads to ... at Northern Westchester Hospital in Mount Kisco, N.Y., said in ... during the day and even to have a snack before ...
Breaking Medicine News(10 mins):Health News:Federal Court Overseeing DePuy ASR Hip Lawsuit Set to Convene Conference in January, Bernstein Liebhard LLP Reports 2Health News:Federal Court Overseeing DePuy ASR Hip Lawsuit Set to Convene Conference in January, Bernstein Liebhard LLP Reports 3Health News:Dylan Queen: Cheap Prom Dresses for the UK Market 2Health News:Various Styles of Bamboo Mats in Many Colors from BambooFlooringChina.com 2Health News:LunaDress Provides Professional Tips On Shopping Wedding And Prom Dresses 2
... from recent challenges, effort to reduce costsST. LOUIS, Feb. ... announced today it is in the process of reducing ... is part of an overall cost-cutting program as the ... has encountered a number of substantial challenges over the ...
... 9 Bionovo, Inc. (Nasdaq: BNVI ) ... Ph.D., to the company,s Scientific Advisory Board. Dr. Gustafsson ... with pharmaceutical and biotech companies. "We are very excited ... as we are advancing our discovery platforms," said Isaac ...
... Poll on Children,s Health finds for children without dental ... ARBOR, Mich., Feb. 9 As the nation begins ... health care reforms, one important aspect of health must ... for children. If left untreated, tooth decay in childhood ...
... STAMFORD, Conn., Feb. 9 Practicing Clinicians Exchange (PCE) ... Control and Prevention (CDC) to provide immunization continuing education ... throughout the United States. In recognition of these vital ... will be providing Immunization Updates throughout the year as ...
... SHENZHEN, China, Feb. 9 /PRNewswire-Asia-FirstCall/ -- Mindray Medical,International ... developer, manufacturer and,marketer of medical devices worldwide, today ... the fourth quarter and fiscal year ended December ... 4, 2009. Mindray,s management will,hold an earnings conference ...
... NORD Names Discovery Health Media Partner and MYSTERY DIAGNOSIS Program ... 28, 2009 - - MYSTERY DIAGNOSIS Airs Mondays at ... The National Organization for Rare Disorders (NORD) announced that ... will serve as media and program partners for Rare Disease ...
Cached Medicine News:Health News:KV Pharmaceutical Company Reduces Workforce 2Health News:KV Pharmaceutical Company Reduces Workforce 3Health News:KV Pharmaceutical Company Reduces Workforce 4Health News:KV Pharmaceutical Company Reduces Workforce 5Health News:Jan Ake Gustafsson, M.D., Ph.D., Joins Bionovo's Scientific Advisory Board 2Health News:Jan Ake Gustafsson, M.D., Ph.D., Joins Bionovo's Scientific Advisory Board 3Health News:Jan Ake Gustafsson, M.D., Ph.D., Joins Bionovo's Scientific Advisory Board 4Health News:High Barriers to Dental Care Exist For 12 Million Children 2Health News:High Barriers to Dental Care Exist For 12 Million Children 3Health News:Practicing Clinicians Exchange Forms Partnership with CDC 2Health News:Mindray to Report Fourth Quarter and Fiscal Year 2008 Financial Results on March 4, 2009 2Health News:National Organization for Rare Disorders To Partner With Discovery Health and 'MYSTERY DIAGNOSIS' for Rare Disease Day 2009 2Health News:National Organization for Rare Disorders To Partner With Discovery Health and 'MYSTERY DIAGNOSIS' for Rare Disease Day 2009 3
(Date:12/24/2014)... CHENGDU, China , Dec. 23, 2014 /PRNewswire/ ... a pharmaceutical company that specializes in patented biopharmaceutical, ... active pharmaceutical ingredients (API) today announced that the ... for its Good Manufacturing Practice (GMP) certificate of ... & Drug Administration,s (CFDA). The public notice period ...
(Date:12/24/2014)... 23, 2014  Medical Science Liaisons play a large ... between the medical device industry and key stakeholders, the ... coming years as the device industry relies on them ... research by benchmarking firm, Best Practices, LLC, one area ... edge is by harnessing new technology to enable education. ...
(Date:12/22/2014)... VIEJO, Calif. , Dec. 22, 2014 ... into expanded corporate offices in Aliso Viejo ... announced that due to the tremendous growth and worldwide ... needed. Sales of patented SnoreRx, the anti snore cure ... offices. He said, "We are now in 23 ...
Breaking Medicine Technology:TPI QLF Achieved Public Notice Status of GMP Certification 2TPI QLF Achieved Public Notice Status of GMP Certification 3Role of Medical Science Liaisons Evolving in Medical Device Sector 2
... Beaumont Hospitals, world renowned heart center has expanded and ... the new Ernst Cardiovascular Center at Beaumont Hospital, Royal ... Cardiovascular Center offer breakthrough surgeries and treatments for people ... also the new home for Beaumont,s innovative "7 tests ...
... Riley Powell taught high school English, and spent her summers ... blood in her stool, she thought it was hemorrhoids, from ... she saw her doctor.  At age 34, she was diagnosed ... a colostomy.  Powell opted to travel out of the country ...
Cached Medicine Technology:Beaumont Hospital Opens New Ernst Cardiovascular Center 2New Choices for Colon Cancer Patients 2New Choices for Colon Cancer Patients 3New Choices for Colon Cancer Patients 4
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: