Navigation Links
Hypertension drugs could lower Disability

According to reseasrches, drugs used to treat hypertension could delay muscle loss and disability in seniors. Dr.Graziano Onder, research associate at University of Hopkins has suggested new, beneficial effects of (Angiotensin Converting Enzyme) ACE-inhibitor //drugs, which are widely used for hypertension, beneficial effects on muscle strength and overall physical performance in older adults. This research must be confirmed in future clinical trials.

The Food and Drug Administration has approved such ACE inhibitors as Accupril, Captopril, Altace and Vasotec. The retrospective study at Hokins, published in the medical journal The Lancet, involved analysis of three years of data from 1995 to 1999 on 650 hypertensive and partially disabled women over 60 who participated in the Women's Health and Aging Study, a project of the National Institute on Aging in Bethesda, Md.

The women on continuous ACE inhibitor therapy showed slower loss of walking speed and muscle strength compared to those using other hypertension drugs or using none. During repeated testing over the three-year period, the subjects walking speeds were measured and they were graded on muscle strength.

Correlating that data to pharmaceutical records, the researchers found women on continuous ACE inhibitor therapy had a lower average decline in muscle strength of 2.5 pounds over the three years, as compared to intermittent users of other antihypertensive drugs, at 7.5 pounds and non-users at minus 8.1 pounds.

Continuous ACE inhibitor users had a smaller loss in walking speed -- sixth-tenths of an inch per second compared with intermittent users of ACE inhibitors at 5.3 inches per second, 6.1 inches per second for intermittent users of other antihypertensive drugs and 7 inches per second for non-users.

"If these findings can be confirmed in randomized controlled trials, ACE inhibitors could not only be used as first-line treatment of older adults with h ypertension, but could also be used to slow physical decline in elderly people," Onder said. "However, pharmaceutical companies are not very interested in ACE-inhibitors right now."

ACE inhibitors have been on the market for more than 10 years, he added, and patents are soon expiring. Onder said he would seek governmental grant funding for a new clinical trial. Dr. Marjolein Visser, assistant professor of medicine suggested that muscle strength and loss of muscle strength is such an important factor in the development of disability in old age. The next step will be to find out whether the same results are obtained from a non-disabled population, to see whether people who use these common medications might actually delay the onset of disability in old age.


'"/>




Related medicine news :

1. New viewpoint on Hypertension
2. FDA Approves Remodulin for Pulmonary Hypertension
3. Glaucoma & Ocular Hypertension more likely in patients with refractive errors
4. Hypertension lowered by Bedtime Dosing
5. Better Treatment For Hypertension
6. Treating Pulmonary Arterial Hypertension In Children With Viagra
7. Hypertension Drug of Choice for African Americans
8. Hypertension can be caused by Inhalation of Salt
9. Inhaling Salt Can Lead To Hypertension
10. Elderly Women Remain At Risk From Hypertension
11. Elderly Women Remain At Risk From Hypertension
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/19/2017)... ... ... Braun Industries will be participating as an exhibitor at EMS Today 2017. ... 23-25, 2017 at the Calvin L. Rampton Salt Palace Convention Center in Salt Lake ... on display. , “JEMS is a leader in EMS news and education. ...
(Date:2/19/2017)... ... February 19, 2017 , ... "At your fingertips" electronic ... MEDfx and the Delaware Health Information Network (DHIN) have partnered to improve connectivity ... state-wide health information exchange, DHIN stores and shares real-time health data for more ...
(Date:2/18/2017)... (PRWEB) , ... February 17, ... ... Change for Devicemakers , Sponsored by Axendia, **FDAnews Free Webinar**, March 1, ... Are manufacturers looking to reduce their regulatory burden? Pay dividends in enhanced ...
(Date:2/18/2017)... ... ... Butler Mobility invited Ken Matthews to visit its manufacturing facility and showroom ... impressed with the safety and reliability of the Stannah Stairlift as well as with ... endorsement by Ken Matthews can be heard on News Radio WHP 580 weekdays from ...
(Date:2/18/2017)... ... 2017 , ... Park Cities Pet Sitter President, Joette White, has been featured ... network. The episode, which was posted this week, features a 30-minute interview of ... Park Cities Pet Sitter’s being awarded the 2017 National Association of Professional Pet Sitter’s ...
Breaking Medicine News(10 mins):
(Date:2/16/2017)... Pa. , Feb. 16, 2017 Absorption ... biologics, and medical devices, is pleased to announce that ... has been selected as a winner of the 2017 ... SmartCEO Magazine and recognizes driven executives for their ... work ethic. The awards ceremony and celebration is on ...
(Date:2/16/2017)... 2017  Aralez Pharmaceuticals Inc. (NASDAQ: ARLZ ... announced that executive management will participate in the RBC ... 22-23, 2017. Adrian Adams , Chief Executive Officer, ... p.m. local time on Wednesday, February 22, 2017. ... event may be accessed from the Investors section of ...
(Date:2/16/2017)... YORK , Feb. 16, 2017 Summary ... agreements entered into by the worlds leading healthcare companies. ... Description The Global Allergy ... to partnering deals and agreements entered into by the world,s leading ... - Top deals by value - Deals listed by company ...
Breaking Medicine Technology: