Navigation Links
Hypertension drugs could lower Disability

According to reseasrches, drugs used to treat hypertension could delay muscle loss and disability in seniors. Dr.Graziano Onder, research associate at University of Hopkins has suggested new, beneficial effects of (Angiotensin Converting Enzyme) ACE-inhibitor //drugs, which are widely used for hypertension, beneficial effects on muscle strength and overall physical performance in older adults. This research must be confirmed in future clinical trials.

The Food and Drug Administration has approved such ACE inhibitors as Accupril, Captopril, Altace and Vasotec. The retrospective study at Hokins, published in the medical journal The Lancet, involved analysis of three years of data from 1995 to 1999 on 650 hypertensive and partially disabled women over 60 who participated in the Women's Health and Aging Study, a project of the National Institute on Aging in Bethesda, Md.

The women on continuous ACE inhibitor therapy showed slower loss of walking speed and muscle strength compared to those using other hypertension drugs or using none. During repeated testing over the three-year period, the subjects walking speeds were measured and they were graded on muscle strength.

Correlating that data to pharmaceutical records, the researchers found women on continuous ACE inhibitor therapy had a lower average decline in muscle strength of 2.5 pounds over the three years, as compared to intermittent users of other antihypertensive drugs, at 7.5 pounds and non-users at minus 8.1 pounds.

Continuous ACE inhibitor users had a smaller loss in walking speed -- sixth-tenths of an inch per second compared with intermittent users of ACE inhibitors at 5.3 inches per second, 6.1 inches per second for intermittent users of other antihypertensive drugs and 7 inches per second for non-users.

"If these findings can be confirmed in randomized controlled trials, ACE inhibitors could not only be used as first-line treatment of older adults with h ypertension, but could also be used to slow physical decline in elderly people," Onder said. "However, pharmaceutical companies are not very interested in ACE-inhibitors right now."

ACE inhibitors have been on the market for more than 10 years, he added, and patents are soon expiring. Onder said he would seek governmental grant funding for a new clinical trial. Dr. Marjolein Visser, assistant professor of medicine suggested that muscle strength and loss of muscle strength is such an important factor in the development of disability in old age. The next step will be to find out whether the same results are obtained from a non-disabled population, to see whether people who use these common medications might actually delay the onset of disability in old age.


'"/>




Related medicine news :

1. New viewpoint on Hypertension
2. FDA Approves Remodulin for Pulmonary Hypertension
3. Glaucoma & Ocular Hypertension more likely in patients with refractive errors
4. Hypertension lowered by Bedtime Dosing
5. Better Treatment For Hypertension
6. Treating Pulmonary Arterial Hypertension In Children With Viagra
7. Hypertension Drug of Choice for African Americans
8. Hypertension can be caused by Inhalation of Salt
9. Inhaling Salt Can Lead To Hypertension
10. Elderly Women Remain At Risk From Hypertension
11. Elderly Women Remain At Risk From Hypertension
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/22/2017)... MT (PRWEB) , ... March 22, 2017 , ... Schneider ... to families and business owners throughout the Yellowstone Valley region, is launching a charity ... only zoo and botanical garden in all of Montana State, and is home to ...
(Date:3/22/2017)... OH (PRWEB) , ... March 22, 2017 , ... ... provides asset protection services and financial planning assistance to communities throughout central Ohio, ... Traumatic Brain Injuries. , Estimates from the Department of Defense and the Veteran's ...
(Date:3/22/2017)... ... March 22, 2017 , ... HumanHaus is proud to ... The conventional broom was great when it was invented, but our customers today ... working parents, the social young couple, the empty nesters and retired that want to ...
(Date:3/22/2017)... ... ... Nearly a decade after it was first recommended that men over the ... to stir controversy. The US Preventative Services Task Force (USPSTF) issued a recommendation against ... news from a study published in JAMA Oncology suggests that more men ...
(Date:3/22/2017)... Las Vegas, NV (PRWEB) , ... March 22, ... ... provider of educational programs and training standards for eating disorder specialists and other ... is proud to announce the opening of its 31st annual iaedp Symposium at ...
Breaking Medicine News(10 mins):
(Date:3/22/2017)... FinancialBuzz.com News Commentary ... is strongly contributing to job creation. A recent report ... for the cannabis industry, projects that by 2020, the ... million jobs for American workers. The legal cannabis market ... is projected to grow at a compound annual growth ...
(Date:3/22/2017)... LUND, Sweden , March 22, 2017 ... Saleh and Mr. Ed Tumaian , two global executive ... Tumaian will be joining the Operational Leadership Team and will report ... ... Saleh comes to TFS with 10 years of medical and ...
(Date:3/22/2017)... March 22, 2017 EMD Serono, the biopharmaceutical business ... the U.S. and Canada , today announced ... poster presentation session at the 65 th Annual Pacific ... California on March 24 th .   ... real-world database collected from July 2009 to December 2015 containing ...
Breaking Medicine Technology: