Navigation Links
Hypertension Drug of Choice for African Americans

A beta-blocker called Nebivolol, may be the best drug to control high blood pressure, especially// among black Americans of African origin according to a new study.

At The International Society on Hypertension in Blacks (ISHIB2005), Nebivolol was shown to be statistically significantly better than placebo in reducing systolic and diastolic blood pressure among African-American hypertensive patients in a multicenter, randomized, double-blind, placebo-controlled study.

“Beta-blockers are under-utilized among African Americans due to the perception that this form of anti-hypertensive medication is not effective,” stated Dr. Saunders, who was one of the researcher of the study, he also added: “This study shows that nebivolol lowered blood pressure in a dose-dependent manner and was well-tolerated”.

The study found no statistically significant differences in the incidence of adverse events between the nebivolol and placebo groups. The most commonly reported adverse events were: headache (5.6% vs 4.1%, respectively); dizziness (3.6% vs 0%, respectively); arthralgia (3.6% vs 2.0%, respectively); diarrhea (3.2% vs 2.0%, respectively); fatigue (2.8% vs 0%, respectively); nasopharyngitis (2.4% vs 0%, respectively); and urinary tract infections (2.4% vs 0%, respectively).

Nebivolol is believed to have dual action. It works by selectively blocking beta1-receptors in the heart and other organs of the body and prevents action of noradrenline and adrenaline. It also works as a modest vasodilator via enhanced release of nitric oxide,(2-3) which means it can widen the blood vessels, contributing to the maintenance of arterial pressure levels within the normal range. The combination of these two actions, as a beta-blocker and a direct vasodilator, may help provide a drug therapy that is both effective and better tolerated by the hypertensive patient.

References
1. Weiss, R. Nebivolol in the treatment of patient s with stage 1 and stage 2 hypertension: results of a randomized, double-blind, placebo-controlled study. San Francisco: 20th Annual Scientific Meeting of the American Society on Hypertension. 2005: Poster-251.
2. Zwieten P. Nebivolol and endothelium dysfunction in salt-sensitive Dahl rats. J Hypertens. 2002;20:357.
3. Broeders MAW, Doevendans PA, Bekkers BCAM, et al. Nebivolol: a third-generation beta-blocker that augments vascular nitric oxide release. Circ.2000;102:677.

Further information on Hypertension from Medindia

- High blood pressure (hypertension) is often called the silent killer because you can have it for years without knowing it.

- High blood pressure or hypertension means high pressure (tension) in the arteries. The arteries are the vessels that carry blood from the pumping heart to all of the tissues and organs of the body.

- Blood pressure is typically recorded as the systolic pressure (as the heart beats) over the diastolic pressure (as the heart relaxes between beats). A consistent blood pressure reading of 140/90 mm Hg or higher is considered high blood pressure, another term for hypertension.

For more information read:

http://www.medindia.net/patients/
patientinfo/highbloodpressure_about.htm
'"/>





Related medicine news :

1. New viewpoint on Hypertension
2. Hypertension drugs could lower Disability
3. FDA Approves Remodulin for Pulmonary Hypertension
4. Glaucoma & Ocular Hypertension more likely in patients with refractive errors
5. Hypertension lowered by Bedtime Dosing
6. Better Treatment For Hypertension
7. Treating Pulmonary Arterial Hypertension In Children With Viagra
8. Hypertension can be caused by Inhalation of Salt
9. Inhaling Salt Can Lead To Hypertension
10. Elderly Women Remain At Risk From Hypertension
11. Elderly Women Remain At Risk From Hypertension
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/30/2020)... (PRWEB) , ... March 30, 2020 , ... ... as the coronavirus pandemic sweeps the country. In an effort to keep frontline ... solutions are enabling police interaction with community members while minimizing direct contact. They ...
(Date:3/28/2020)... ... 2020 , ... With social distancing, or more accurately physical ... people of all ages are challenged to find different ways to connect socially. ... best of times—the physical distance mandated to prevent the pandemic’s spread can be ...
(Date:3/28/2020)... ... March 27, 2020 , ... To ... is now offering telemedicine as an alternative approach to seeing their patients. This ... in the comfort of their own home or office using video conference and ...
(Date:3/28/2020)... ... March 28, 2020 , ... iPatientCare, a ... management, and patient engagement solutions has expanded the availability of telehealth services and ... of crisis, telemedicine has a big role in fighting coronavirus . Increasing ...
(Date:3/27/2020)... ... March 27, 2020 , ... Justin P. ... Top Docs. Dr. Kubeck has been approved every year consecutively since 2016. Dr. ... in Spinal Surgery. , Dr. Kubeck’s medical education began at Thomas Jefferson ...
Breaking Medicine News(10 mins):
(Date:4/5/2020)... (PRWEB) , ... April 04, 2020 , ... ... their baby blanket manufacturing facility into a factory producing non-medical cloth facemasks. , ... strategy to approve the use of non-medical cloth face masks if no medical-grade ...
(Date:4/5/2020)... , ... April 04, 2020 , ... ... infections, urgent needs arise for medical supplies, diagnostics, and treatments. Shortages of such ... professionals at risk. , Tran & Associates supports the fight against ...
(Date:4/2/2020)... (PRWEB) , ... April 02, 2020 , ... NCPDP has ... at the Meeting of the NCPDP Board of Trustees on Wednesday, May 6, 2020. ... Pooja Babbrah, M.B.A., PBM Practice Lead, Point-of-Care Partners, newly elected to the Board of ...
Breaking Medicine Technology: