Navigation Links
Hypertension Drug of Choice for African Americans

A beta-blocker called Nebivolol, may be the best drug to control high blood pressure, especially// among black Americans of African origin according to a new study.

At The International Society on Hypertension in Blacks (ISHIB2005), Nebivolol was shown to be statistically significantly better than placebo in reducing systolic and diastolic blood pressure among African-American hypertensive patients in a multicenter, randomized, double-blind, placebo-controlled study.

“Beta-blockers are under-utilized among African Americans due to the perception that this form of anti-hypertensive medication is not effective,” stated Dr. Saunders, who was one of the researcher of the study, he also added: “This study shows that nebivolol lowered blood pressure in a dose-dependent manner and was well-tolerated”.

The study found no statistically significant differences in the incidence of adverse events between the nebivolol and placebo groups. The most commonly reported adverse events were: headache (5.6% vs 4.1%, respectively); dizziness (3.6% vs 0%, respectively); arthralgia (3.6% vs 2.0%, respectively); diarrhea (3.2% vs 2.0%, respectively); fatigue (2.8% vs 0%, respectively); nasopharyngitis (2.4% vs 0%, respectively); and urinary tract infections (2.4% vs 0%, respectively).

Nebivolol is believed to have dual action. It works by selectively blocking beta1-receptors in the heart and other organs of the body and prevents action of noradrenline and adrenaline. It also works as a modest vasodilator via enhanced release of nitric oxide,(2-3) which means it can widen the blood vessels, contributing to the maintenance of arterial pressure levels within the normal range. The combination of these two actions, as a beta-blocker and a direct vasodilator, may help provide a drug therapy that is both effective and better tolerated by the hypertensive patient.

References
1. Weiss, R. Nebivolol in the treatment of patient s with stage 1 and stage 2 hypertension: results of a randomized, double-blind, placebo-controlled study. San Francisco: 20th Annual Scientific Meeting of the American Society on Hypertension. 2005: Poster-251.
2. Zwieten P. Nebivolol and endothelium dysfunction in salt-sensitive Dahl rats. J Hypertens. 2002;20:357.
3. Broeders MAW, Doevendans PA, Bekkers BCAM, et al. Nebivolol: a third-generation beta-blocker that augments vascular nitric oxide release. Circ.2000;102:677.

Further information on Hypertension from Medindia

- High blood pressure (hypertension) is often called the silent killer because you can have it for years without knowing it.

- High blood pressure or hypertension means high pressure (tension) in the arteries. The arteries are the vessels that carry blood from the pumping heart to all of the tissues and organs of the body.

- Blood pressure is typically recorded as the systolic pressure (as the heart beats) over the diastolic pressure (as the heart relaxes between beats). A consistent blood pressure reading of 140/90 mm Hg or higher is considered high blood pressure, another term for hypertension.

For more information read:

http://www.medindia.net/patients/
patientinfo/highbloodpressure_about.htm
'"/>





Related medicine news :

1. New viewpoint on Hypertension
2. Hypertension drugs could lower Disability
3. FDA Approves Remodulin for Pulmonary Hypertension
4. Glaucoma & Ocular Hypertension more likely in patients with refractive errors
5. Hypertension lowered by Bedtime Dosing
6. Better Treatment For Hypertension
7. Treating Pulmonary Arterial Hypertension In Children With Viagra
8. Hypertension can be caused by Inhalation of Salt
9. Inhaling Salt Can Lead To Hypertension
10. Elderly Women Remain At Risk From Hypertension
11. Elderly Women Remain At Risk From Hypertension
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/24/2017)... , ... June 24, 2017 , ... The weather is ... time outdoors. Home and business owners should be aware that the summer months provide ... In fact, mechanical locks and keys can be negatively affected from direct exposure to ...
(Date:6/23/2017)... ... June 23, 2017 , ... The Rhode Island Quality ... Management Alerts and Dashboards, an innovative new service enabling healthcare providers to proactively ... Management Alerts and Dashboards provide near real-time data about patients admitted to and/or ...
(Date:6/23/2017)... , ... June 23, 2017 , ... By scoring 100% ... ninth consecutive four-star rating from premier online charity evaluator, Charity Navigator, validating ANRF's work ... 1% of all charities reviewed by Charity Navigator and earns ANRF a spot on ...
(Date:6/23/2017)... , ... June 24, 2017 , ... Studies show evidence ... reduce the risk of visual loss in these patients. , But how often do ... or smoking cessation to patients at risk of or with early symptoms of AMD? ...
(Date:6/23/2017)... (PRWEB) , ... June 23, 2017 , ... ... plastic surgeon practicing in Newburgh, New York, has recently begun offering three new ... to offering the best cutting-edge procedures and reducing downtime, Dr. Rubinstein is excited ...
Breaking Medicine News(10 mins):
(Date:6/1/2017)... June 1, 2017 Nutriceutical Holdings (NH), parent ... Solutions (VRS), and KD Pharma Group have decided to ... by KD Pharma Group. KD Pharma Group will become ... to acquire the entire company. "We believe ... are committed to growing the NH companies by providing ...
(Date:5/26/2017)... 26, 2017  Endo International plc (NASDAQ: ENDP ... CEO, will represent the Company in a fireside chat at ... Tuesday, June 13, 2017 at 10:40 a.m. PT / 1:40 ... in Rancho Palos Verdes, CA. ... will be available on the Company,s website at http://www.endo.com/investors/overview ...
(Date:5/22/2017)...  As the specialty pharmacy industry and the ... the revolutionary shift from volume-based to value-based care, ... patient outcomes and shaping the future of the ... from clinical trials and toward data that reveals ... therapy utilization in precise patient populations. Therigy ® ...
Breaking Medicine Technology: