Navigation Links
Hypertension Drug of Choice for African Americans

A beta-blocker called Nebivolol, may be the best drug to control high blood pressure, especially// among black Americans of African origin according to a new study.

At The International Society on Hypertension in Blacks (ISHIB2005), Nebivolol was shown to be statistically significantly better than placebo in reducing systolic and diastolic blood pressure among African-American hypertensive patients in a multicenter, randomized, double-blind, placebo-controlled study.

“Beta-blockers are under-utilized among African Americans due to the perception that this form of anti-hypertensive medication is not effective,” stated Dr. Saunders, who was one of the researcher of the study, he also added: “This study shows that nebivolol lowered blood pressure in a dose-dependent manner and was well-tolerated”.

The study found no statistically significant differences in the incidence of adverse events between the nebivolol and placebo groups. The most commonly reported adverse events were: headache (5.6% vs 4.1%, respectively); dizziness (3.6% vs 0%, respectively); arthralgia (3.6% vs 2.0%, respectively); diarrhea (3.2% vs 2.0%, respectively); fatigue (2.8% vs 0%, respectively); nasopharyngitis (2.4% vs 0%, respectively); and urinary tract infections (2.4% vs 0%, respectively).

Nebivolol is believed to have dual action. It works by selectively blocking beta1-receptors in the heart and other organs of the body and prevents action of noradrenline and adrenaline. It also works as a modest vasodilator via enhanced release of nitric oxide,(2-3) which means it can widen the blood vessels, contributing to the maintenance of arterial pressure levels within the normal range. The combination of these two actions, as a beta-blocker and a direct vasodilator, may help provide a drug therapy that is both effective and better tolerated by the hypertensive patient.

References
1. Weiss, R. Nebivolol in the treatment of patient s with stage 1 and stage 2 hypertension: results of a randomized, double-blind, placebo-controlled study. San Francisco: 20th Annual Scientific Meeting of the American Society on Hypertension. 2005: Poster-251.
2. Zwieten P. Nebivolol and endothelium dysfunction in salt-sensitive Dahl rats. J Hypertens. 2002;20:357.
3. Broeders MAW, Doevendans PA, Bekkers BCAM, et al. Nebivolol: a third-generation beta-blocker that augments vascular nitric oxide release. Circ.2000;102:677.

Further information on Hypertension from Medindia

- High blood pressure (hypertension) is often called the silent killer because you can have it for years without knowing it.

- High blood pressure or hypertension means high pressure (tension) in the arteries. The arteries are the vessels that carry blood from the pumping heart to all of the tissues and organs of the body.

- Blood pressure is typically recorded as the systolic pressure (as the heart beats) over the diastolic pressure (as the heart relaxes between beats). A consistent blood pressure reading of 140/90 mm Hg or higher is considered high blood pressure, another term for hypertension.

For more information read:

http://www.medindia.net/patients/
patientinfo/highbloodpressure_about.htm
'"/>





Related medicine news :

1. New viewpoint on Hypertension
2. Hypertension drugs could lower Disability
3. FDA Approves Remodulin for Pulmonary Hypertension
4. Glaucoma & Ocular Hypertension more likely in patients with refractive errors
5. Hypertension lowered by Bedtime Dosing
6. Better Treatment For Hypertension
7. Treating Pulmonary Arterial Hypertension In Children With Viagra
8. Hypertension can be caused by Inhalation of Salt
9. Inhaling Salt Can Lead To Hypertension
10. Elderly Women Remain At Risk From Hypertension
11. Elderly Women Remain At Risk From Hypertension
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/5/2016)... ... February 05, 2016 , ... Stuart Bentkover, MD, FACS ... Designed to provide the most effective tattoo removal today, Dr. Bentkover is the only ... Developed by Cynosure, the PicoSure has been approved by the Food and Drug Administration ...
(Date:2/5/2016)... ... 05, 2016 , ... Colorize is a web theme package created ... next using Colorize's dynamic moving camera. Colorize is perfect for personal and web related ... environment with 1 to 5 focus points per scene, stage floor scene presets that ...
(Date:2/5/2016)... ... ... Health and wellness is a topic that should concern all Americans; however, ... an illness. Migraines are a severe form of a headache and often are accompanied ... the pain on their worst enemy, the feeling can last for many hours and ...
(Date:2/5/2016)... Ramsey, NJ (PRWEB) , ... February 05, 2016 ... ... Optimizing Primary Care for Patients with Rare Diseases, a continuing medical education (CME) ... conference is the first of its kind—and a first for ACCORD, whose mission ...
(Date:2/5/2016)... ... February 05, 2016 , ... KICVentures ( http://www.kicventures.com ) announced ... in New York City on Thursday, January 21, 2016. Kingsley R. Chin, ... alumnus of the varsity Columbia soccer program) spoke at the event, offering professional ...
Breaking Medicine News(10 mins):
(Date:2/4/2016)...  The Senior Care Pharmacy Coalition (SCPC) today ... Jason Chaffetz (R-UT) and Ranking Member ... , "Developments in the Prescription Drug Market," to ... about abusive pharmacy benefit manager (PBM) pricing practices. ... Member Elijah Cummings (D-MD) are diligent, serious lawmakers ...
(Date:2/4/2016)... , Feb. 4, 2016  Montoya Love is ... in the field of Pharmaceuticals. Montoya is the Regulatory ... Manufacturing and ... Becton Dickinson provides healthcare institutions, clinical laboratories ... throughout fifty countries across the globe. ...
(Date:2/4/2016)... Mettler-Toledo International Inc. (NYSE: MTD ) today announced ... highlights: , Sales in local currency increased ... Reported sales decreased 3% as currency reduced sales growth ... per diluted share as reported (EPS) were $4.44, compared ... was $4.65, an increase of 10% over the prior-year ...
Breaking Medicine Technology: