Navigation Links
Hydroxyurea derivatives kill colon cancer cells

A new class of drugs based on a widely used anticancer drug, hydroxyurea, shows potent colon cancer-killing effects in the laboratory and in mice, according to researchers. The new compounds seem to be very interesting for the treatment of these tumors. //

Previous drugs derived from hydroxyurea were extremely active in blocking the same cell targets as hydroxyurea, but had serious side effects. This prompted the researchers to synthesize similar drugs with different structures that they hypothesized would be less likely to cause complications.

The researchers tested the drugs against colon cancer implants in mice. One of the compounds, EPH116, blocked the tumor growth at doses that did not appear toxic. EPH116 brought considerable cancer cell death, but did so by as yet unknown mechanisms. In the laboratory, EPH116 and its relatives also showed activity against small cell lung cancer and malignant melanoma cells.


'"/>




Page: 1

Related medicine news :

1. Hydroxyurea Treatment For Children With Sickle Cell Disease
2. Benzotiophene derivatives exhibit antitumor activity
3. Radiotherapy helps in colon cancer
4. Benefit of colonoscopy
5. Wheat wards off colon cancer
6. Defeating colon cancer
7. Calcium reduces colon cancer risk
8. Smoking risk precedes colon cancer
9. Implication of virus in colon cancer
10. New virtual colonoscopy procedure for easier colon screening
11. Long-term use of calcium supplements to prevent colon cancer
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/18/2017)... (PRWEB) , ... August 18, 2017 , ... ... and financial planning assistance that serves communities throughout southern Florida, is working to ... provide scholarship assets to children from low income families. , The Take Stock ...
(Date:8/18/2017)... ... ... The Golseth Agency, a Texas based insurance management and financial planning assistance provider ... organized to provide support to Christina Upchurch and her two children after the loss ... returned from out of town to find her husband passed away and their home ...
(Date:8/18/2017)... ... 18, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The House of Yahweh in Abilene, ... on false teachings pertaining to the mother of the Savior whom the world calls “Mother ... different picture of the role of this historical woman. , “The world bows, kisses ...
(Date:8/18/2017)... Vermont (PRWEB) , ... August 18, 2017 , ... ... phone numbers and call tracking and monitoring solutions, announced today the launch of ... site include a modern navigation and aesthetic, fully responsive design, and an enhanced ...
(Date:8/18/2017)... ... August 18, 2017 , ... “Three Narrow Roads”: a vivid and provocative ... published author, Rev. Dr. Burnett King Sr., is currently the pastor-teacher-visionary at Simply the ... Faith Track Club, Inc., a track-and-field program geared towards youth. , King shares, “When ...
Breaking Medicine News(10 mins):
(Date:8/8/2017)... Aug. 8, 2017   ... diluted (GAAP) loss per share from continuing operations ... revenues increased 16 percent to $110 million ... 27 percent to $161 million ... from continuing operations increased 8 percent to $0.93 ...
(Date:8/7/2017)... , Aug. 7, 2017  Endo International plc ... reached agreements to resolve virtually all known U.S. mesh ... discussions to resolve the known remaining U.S. claims at ... payments beginning in the fourth quarter of 2017 and ... of its second quarter 2017 results, the Company intends ...
(Date:8/2/2017)... , Aug. 2, 2017   Marshall County Hospital in Benton, ... proactively reduce the risk of hospital-acquired infections (HAIs). The new addition, Tru-D SmartUVC , ... energy to kill deadly pathogens such as C. diff , MRSA, MERS, Ebola and ... Tru-D SmartUVC ... Tru-D in action in a patient room ...
Breaking Medicine Technology: