Navigation Links
Human Stem Cell Therapy Restores Motor Function to Paralyzed Rats

Scientists at the University of California, San Diego (UCSD) School of Medicine have successfully restored motor function in paralyzed rats by grafting human spinal stem cells (hSSCs) in them.

"We demonstrated that when damage has occurred due to a loss of blood flow to the spines neural cells, by grafting human neural stem cells directly into the spinal cord we can achieve a progressive recovery of motor function," said lead researcher Dr. Martin Marsala, Professor of Anesthesiology, whose study has been published in the journal Neuroscience.

"This could some day prove to be an effective treatment for patients suffering from the same kind of ischemia-induced paralysis," he added.

The researchers are currently testing the safety and efficacy of human stem cell therapy in other animal models, and may begin clinical trials in humans by next year.

Sixteen rats were induced spinal cord ischemia during the study, and then they were injected with with human spinal stem cells 21 days after paralysis. The researchers also injected seven other rats with with medium that did not contain stem cells.

They found that three of the nine rats injected with hSSCs returned to walking at six weeks, and three others had improved mobility in all lower extremity joints. All nine animals achieved significantly better motor scores than those in the control group, and showed a consistent presence of transplanted cells in the spinal area.

It was also seen that the majority of transplanted human spinal stem cells survived, and became mature neurons, according to Marsala. The researcher revealed that a second study conducted over a three-month period also furnished similar results.

The researchers believe that the therapy may eventually prove even more effective in human patients.

"Physical therapy may accelerate integration of the grafted stem cells and enhance their therapeutic be nefit," said co-author Karl Johe, a researcher at Neuralstem, the company that manufactures the hSSCs used in the study.

The researchers say that their main goal is to provide a significant gain in functional mobility of the patients legs.

"These research findings could offer great hope to people with spinal ischemic injury who suffer from resulting spasticity and rigidity," said Marsala.


'"/>




Related medicine news :

1. Human Genome Project Achieves Technological Triumph
2. First Vaccine Designed for Africa Cleared for Testing in Humans
3. Human gene number increases
4. Scientists found ancient Human Germ Killer
5. New standards for Human Research Safety
6. Human wasting disease linked to a gene
7. The Human Mad Cow Case
8. Human Growth Hormone Found To be Dangerous For Human Use
9. Human Antibody That Can Block SARS
10. Human immunity system can battle HIV.
11. Two New Human Papilloma virus (HPV) vaccines to prevent cervical cancer
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/31/2016)... , ... May 31, 2016 , ... ... 4, 2016 Cool Vendors in Security Infrastructure Protection report by Gartner1 Inc. , ... a series of research reports evaluating these innovative vendors and their products and ...
(Date:5/31/2016)... (PRWEB) , ... May 31, 2016 , ... ... multichannel marketing services firm and statement solutions provider, for the tenth consecutive ... the May 2016 issue of Advertising Age, and SourceLink ranked eighteenth in the ...
(Date:5/31/2016)... N.J. (PRWEB) , ... May 31, 2016 , ... ... and print media enterprise focused on patients with cancer, has added Cancer ... readers and website visitors with more timely content on continuing successful careers while ...
(Date:5/30/2016)... ... May 30, 2016 , ... As the CDC relaxes ... children and their efforts to keep their households lice free. , According to ... enacting new policies that keep kids in the classroom despite the fact that they ...
(Date:5/30/2016)... ... May 30, 2016 , ... Zane Benefits, ... publication of an original infographic, " Health Benefits Reimbursement Compliance Timeline ." ... Zane Benefits complies with various federal regulations and reforms. , Navigating the new ...
Breaking Medicine News(10 mins):
(Date:5/26/2016)... ALBANY, New York , May 26, 2016 ... Transparency Market Research "Medical Waste Management Market - U.S. Industry ... the medical waste management market in the U.S. was valued ... expand at a CAGR of 3.4% from 2015 to 2023 ... report provides exhaustive analysis of current and emerging needle free ...
(Date:5/26/2016)... May 26, 2016   Change Healthcare ... analytics, network solutions and technology-enabled services designed ... entered into a strategic channel partnership with ... software solutions and revenue cycle management services ... and rehabilitation clinics to optimize revenue, operational ...
(Date:5/25/2016)... -- According to a new market research ... by Therapeutic Area (Oncology, Cosmeceutical/Plastic Surgery), by Application (Drug ... Hospitals/ Clinics) - Forecast to 2021", published by MarketsandMarkets, ... the forecast period of 2016 to 2021. This market ... from USD 117.3 Million in 2016, at a CAGR ...
Breaking Medicine Technology: