Navigation Links
Hormone therapy may affect heart attack severity in women

Recent studies undertaken at Wake Forest University Baptist Medical Center researcher and colleagues, showed promising signs after research in monkeys suggested //that the type of progestin in hormonal therapy could in fact affect heart attack severity.

At an annual meeting of the North American Menopause Society in Washington, D.C. today, Dr. J. Koudy Williams who is the lead investigator from Wake Forest Baptist formally announced, “One type of hormone therapy limited heart muscle damage to only 5 percent while another resulted in permanent damage to 35 percent of muscle. If we can learn more about this mechanism we might be able to identify better hormone therapies for postmenopausal women."

Hormone therapy had been prescribed for several years as a way to prevent heart vessel disease in women. However after several research studies, including the Women's Health Initiative, it was found that combination therapy (estrogen plus progestin) increased the risk of both a first and second heart attack in older women. These studies though holistic in itself did not look at the amount of heart damage that occurs if a postmenopausal woman has a heart attack. Dr Williams went on to say that it is gravely impotent to know this information as many women take combination therapy drugs for menopausal symptoms or to protect their bones even though the drugs are no longer recommended to prevent heart disease.

In a study of postmenopausal monkeys, Williams and colleagues compared the protestin in Prempro?, the most widely prescribed hormone therapy, with the progestin in Femhrt.

One group of monkeys where given estrogen and the Femhrt progestin, while a second group where given estrogen and the Prempro progestin and a third group where not given any hormone therapy. The monkey were given these drugs for a period of one year in the doses equivalent to those prescribed to women.

The researchers then measured the amount of irreversible muscle damage that resulted after an experimentally produced heart attack. They found that the two progestins produced dramatically different results. The Femhrt group had 5 percent muscle damage, the group that didn't take hormone therapy had 20 percent damage, and the Prempro group had 35 percent damage.

The amount of heart muscle damage can affect risk of a future heart attack and risk of developing heart failure, the inability of the heart to meet the body's demands.

Williams said the results suggest that all hormone therapy drugs are not the same and that there may be better treatments than current formulations. He said, however, that the results are too preliminary to apply to women. The researches still have a long way to go. They want to learn how estrogen alone - without a progestin - will affect the amount of muscle damage, and what caused the differences in muscle damage. They suspect that it is related to the amount of inflammation that occurs after a heart attack. The group, wants to see how soy, which has anti-inflammatory properties, would affect muscle damage.

Other researchers were Irma Suparto, M.D., from the Institute Pertanian Bogor in Indonesia and Jacob Vinten-Johansen, Ph.D., a professor or surgery at Emory University.


'"/>




Related medicine news :

1. Levothyroxine Thyroid Hormone Replacement, Approved for Hypothyroidism
2. Hormone replacement Therapy a headache
3. Ovarian cancer in relationship with Hormone therapy
4. Hormone contraceptives lead to bone problems
5. Hormone treatment helps obese people slim down
6. Hormone Deficiency Results In Miscarriage
7. Hormones Linked To Migraines
8. Hormone replacement therapy helps women
9. Decrease of Hunger Hormone after Obesity Surgery
10. Possible benefits of Hormone Replacement Therapy
11. Hormone replacement therapy improves sexual function
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/23/2017)... ... May 23, 2017 , ... Therachat , a smart ... in an infographic on the current state of anxiety in support of National Mental ... was conducted in April 2017 and benchmarked general anxiety levels as well as identified ...
(Date:5/22/2017)... NC (PRWEB) , ... May 22, 2017 , ... ... Matthews Periodontics, is now welcoming new patients with periodontal plastic surgery treatments, including ... from a general dentist. Dr. Green provides these esthetic and functional procedures to ...
(Date:5/22/2017)... ... May 22, 2017 , ... Galena, Alaska, has a population of less ... headlines when it was targeted to build a nuclear plant by the TOSHIBA Corporation. ... manager Marvin L. Yoder describes the journey to get power to his small town, ...
(Date:5/21/2017)... (PRWEB) , ... May 19, 2017 , ... Chris Cornell, 52, was found dead on ... why one of the most respected lead singers in the rock industry would take his ... of mental illness. FindaTopDoc investigates how mental illness played a role in the death of ...
(Date:5/21/2017)... PARK, FL (PRWEB) , ... May 20, 2017 , ... ... sell it, find it, review it, and share its attributes like never before. More ... dispensary directory to connect cannabis enthusiasts to stores, strains, products – and for the ...
Breaking Medicine News(10 mins):
(Date:5/8/2017)...  Diplomat Pharmacy, Inc. (NYSE: DPLO)., has completed its ... health care service center company based in ... relationship management programs for leading pharmaceutical manufacturers and health ... WRB will join Envoy Health Management, LLC , ... biotech firms, and other service companies. Together, WRB and ...
(Date:5/4/2017)... May 4, 2017  A recent study published ... Ultraviolet-C light as a means of disinfection ... to reduce bioburden on anesthesia workstations. In the ... high-touch, complex medical equipment surfaces contaminated with three ... "This study further validates the body of ...
(Date:5/4/2017)... 2017   BioLife Solutions , Inc. (NASDAQ: ... of proprietary clinical grade hypothermic storage and ... today announced that the Company,s first quarter 2017 financial ... May 11, 2017, and that the Company will host ... PT that afternoon. Management will provide an overview of ...
Breaking Medicine Technology: