( Recent studies undertaken at Wake Fores...)Hormone therapy may affect heart attack severity in women,Health

Recent studies undertaken at Wake Forest University Baptist Medical Center researcher and colleagues, showed promising signs after research in monkeys suggested //that the type of progestin in hormonal therapy could in fact affect heart attack severity.

At an annual meeting of the North American Menopause Society in Washington, D.C. today, Dr. J. Koudy Williams who is the lead investigator from Wake Forest Baptist formally announced, “One type of hormone therapy limited heart muscle damage to only 5 percent while another resulted in permanent damage to 35 percent of muscle. If we can learn more about this mechanism we might be able to identify better hormone therapies for postmenopausal women."

Hormone therapy had been prescribed for several years as a way to prevent heart vessel disease in women. However after several research studies, including the Women's Health Initiative, it was found that combination therapy (estrogen plus progestin) increased the risk of both a first and second heart attack in older women. These studies though holistic in itself did not look at the amount of heart damage that occurs if a postmenopausal woman has a heart attack. Dr Williams went on to say that it is gravely impotent to know this information as many women take combination therapy drugs for menopausal symptoms or to protect their bones even though the drugs are no longer recommended to prevent heart disease.

In a study of postmenopausal monkeys, Williams and colleagues compared the protestin in Prempro?, the most widely prescribed hormone therapy, with the progestin in Femhrt.

One group of monkeys where given estrogen and the Femhrt progestin, while a second group where given estrogen and the Prempro progestin and a third group where not given any hormone therapy. The monkey were given these drugs for a period of one year in the doses equivalent to those prescribed to women.

The researchers then measured the
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