Navigation Links
Hormone Therapy May Improve the Trip Down Memory Lane

Many women experience declines in their memory during and after menopause, a change thought to be due, in part, to the rapid hormonal changes they weather during that time. //

Now, research from the University of Michigan Health System suggests that hormone therapy might help women retain certain memory functions. In a study in the new issue of The Journal of Clinical Endocrinology & Metabolism, they report that a group of postmenopausal women showed more brain activity during a visual memory test than did women who were not taking the hormone therapy.

The 10 postmenopausal women in the study, ages 50-60, were given hormone therapy or a placebo for four weeks, followed by a month with no medications, and then four weeks of the other treatment. Their brain activation was measured as they were shown a complex grid of 81 squares, with 40 of them darkened to form a pattern.

Participants were asked to find the matching image from a choice of two, with the new set of images presented after varying time periods (one to four seconds). During the time that the two images were shown, participants were asked to choose the one that matched the initial grid by pressing one of two buttons on an MRI (magnetic resonance imaging)-compatible response pad.

Those who were taking combined estrogen-progestin hormone therapy showed significantly increased activity in the prefrontal cortex, a region of the brain that is critical in memory tasks, compared with those on placebo (a pill with no medicinal value). The researchers used images from functional MRI, or fMRI, to compare the participants’ brain activity.

“Our findings suggest that even relatively short periods of hormone therapy have effects on the memory systems that may be of benefit to some women during the perimenopausal transition or early postmenopause,” says lead author Yolanda R. Smith, M.D., associate professor in the Department of Obstetrics and Gynecology at the U -M Medical School.

“Other studies have indicated that long-term hormone therapy is not beneficial for the prevention of chronic illnesses,” Smith says. “But our study indicates that the effects of short-term hormone therapy on brain circuitry and function warrant further study.”

The role of estrogen in maintaining brain function is of great significance as the population ages and the incidence of dementia increases, says senior author Jon-Kar Zubieta, M.D., Ph.D., associate professor of psychiatry and radiology at the U-M Medical School and associate research scientist at U-M’s Molecular & Behavioral Neuroscience Institute (MBNI).

Zubieta notes that working memory – that is, a limited-capacity storage system that allows the brain to actively maintain and manipulate information that is critical for conducting many daily activities over short time periods – has been demonstrated to be less efficient in older adults. This decline has been linked with changes in the prefrontal cortex.

“Our finding of increased activation in the prefrontal cortex in older women using hormone therapy is important and suggestive of potential therapies that need to be explored further,” he says. “Eventually, this could lead to new options for women as they enter a time when memory problems typically develop.”

Source-Neswise
SRM
'"/>




Related medicine news :

1. Levothyroxine Thyroid Hormone Replacement, Approved for Hypothyroidism
2. Hormone replacement Therapy a headache
3. Ovarian cancer in relationship with Hormone therapy
4. Hormone contraceptives lead to bone problems
5. Hormone treatment helps obese people slim down
6. Hormone Deficiency Results In Miscarriage
7. Hormones Linked To Migraines
8. Hormone replacement therapy helps women
9. Decrease of Hunger Hormone after Obesity Surgery
10. Possible benefits of Hormone Replacement Therapy
11. Hormone replacement therapy improves sexual function
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/5/2016)... Seattle, WA (PRWEB) , ... May 05, 2016 ... ... one ranking for overall select performance in the industry’s gold standard KLAS ... Expertise? The Epic Consulting report assessed organizations that specialize in consulting services ...
(Date:5/5/2016)... ... May 05, 2016 , ... The U.S. Food ... requiring e-cigarette manufacturers to submit their products through an arduous federal approval process. ... products that entered the market since February 15, 2007. That would essentially ban ...
(Date:5/5/2016)... ... May 05, 2016 , ... TLC Laser Eye Centers ... California. The laser eye center will now be called “Gordon Schanzlin New Vision Institute, ... will remain at the full-service facility to ensure that patients continue to receive the ...
(Date:5/5/2016)... , ... May 05, 2016 , ... ... macroalgae can use ultraviolet light A (UV-A) for photosynthesis, researchers Juntian Xu and ... green, and brown seaweeds. The pair observed that when photosynthetically active radiation (i.e. ...
(Date:5/5/2016)... , ... May 05, 2016 , ... ... organization, announces McLaughlin & Smoak Benefits as the latest addition to its family ... has a dedicated team of compliance, wellness, human resources, and health care consumerism ...
Breaking Medicine News(10 mins):
(Date:5/5/2016)... 5, 2016 ... of the  "Europe Thrombocythemia Market and ... to their offering.       ... ,The latest research Europe Thrombocythemia Market ... provides comprehensive insights into Thrombocythemia pipeline ...
(Date:5/4/2016)...  Compass Diversified Holdings (NYSE: CODI ) ... leading middle market businesses, announced today its consolidated operating ... First Quarter 2016 Highlights , Generated ... "Cash Flow") of $13.6 million for the first quarter ... million for the first quarter of 2016; , ...
(Date:5/4/2016)... 2016 According to market research "Global ... Forecast to 2022 - Industry Insights by Slice Type (High, ... Others)" by P&S Market Research, the global computed tomography ... it is expected to grow at a CAGR of 5.0% ... segment is expected to witness the faster growth, CAGR of ...
Breaking Medicine Technology: