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Hormone Replacement Therapy Can Reduce Heart attacks On Woman Under 60

and fractures in postmenopausal women had initially reported that HRT was linked to more heart attacks when they analysed the sample as a whole, in women with a mean age of 63 years, rather than breaking down women's ages after menopause. He explained that this is important because younger women may respond differently to HRT than older women. He said that now the WHI researchers had provided data for coronary heart disease events for younger and older women separately.

Salpeter and his colleagues, including his daughter, lead author Shelley Salpeter, a clinical professor of medicine at Stanford's School of Medicine and a physician at Santa Clara Valley Medical Center in San Jose, Calif, together pooled the data from the two WHI trials for younger women with all other randomised placebo-controlled trials and found a statistically significant 32 percent reduction in coronary heart disease events for women who start treatment in their 50s.

The study also found that HRT significantly reduces the risk of diabetes compared with placebo but increases the levels of a protein associated with inflammation in the body. This may reduce heart attacks in younger women without heart disease but increase the risks for older women who already have cardiovascular disease.

Salpeter explained that the most recent study shows that HRT reduces coronary heart disease events in women who start treatment shortly after menopause. Yet, other studies suggest that HRT increases the risk of breast cancer but reduces risk of colorectal cancer. Thus, younger postmenopausal women need to consult their physicians and weigh their medical histories to decide whether HRT is right for them.


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