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Hope for Marburg treatment: vaccine successful in primates

The deadly Marburg virus that had affected a total of 423 cases in Angola,// which had left 357 dead, may finally have a treatment in the form of a vaccine.

A virus causes Marburg hemorrhagic fever from the same family of virus that cause Ebola hemorrhagic fever. The disease is a rare condition but have the potential of causing an outbreak very fast. The symptoms begin with severe headaches and feeling of severe unwell. Patients develop severe hemorrhagic manifestations and often turn fatal with bleedings from various locations. There is no specific treatment currently available.

In another trial a few years ago, researchers from National Institutes of Health, US, had developed a vaccine from dead virus called adenovirus. This vaccine had protected macaques from the Ebola virus.

In a new research, scientists from Public Health Agency of Canada have developed the vaccine from live deactivated virus that is said to be more effective as it is required in small doses and is easier to produce. The vaccine is med from the virus that causes the disease vesicular stomatitis in the farm animals. After genetically modifying the virus to make it harmless, inoculations of the live virus makes the human bodies to identify the protein coverings of the virus and makes them fight the virus of Ebola and Marburg. The scientists had been able to successfully test the vaccine in macaques
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