Navigation Links
High Doses Of Common Pain killers Can Double The Chances Of Heart attack

A study by researchers at the Oxford have found that high doses of the common painkiller like ibuprofen, which is available without prescription, doubles the risk of a heart attack if taken in high doses for a long time//. But the British Medical Journal study also explains that there was no danger for occasional users, and its risks were moderate when compared to the benefits for patients who depend on it to lead normal lives. They claimed to have found that only an extra 3 people in every 1000 suffered from the adverse reaction.

In the past the long-term use of non-steroidal anti-inflammatory (NSAID) drugs like Ibuprofen, Diclofenac have often raised fears. These drugs are very widely used medications for relief from headaches, period pains and discomfort caused by inflammation. They are used daily by millions of arthritis sufferers. There are increasing concerns on the newer COX-2 drugs, being raised along with the NSAIDs. These COX-2 drugs are given to avoid side effects like gastric bleeding and ulcers that could sometimes occur with the painkillers.

Vioxx, one COX-2, drug was taken off the market after there were concerns about its risk of causing a heart attack. Studies had also shown that the risk of heart attacks and strokes were greatly increased with other NSAIDs but clear results have not yet emerged. The researchers from Oxford University found that, in patients taking COX-2s, the odds of a heart attack or stroke increased by 42% compared with placebo. They found that the odds were increased by 51% for high-dose ibuprofen (800mg three times a day) and 63% for high-dose diclofenac (75mg twice a day). They also found that Naproxen another NSAID, also had no association with any increased risk of cardiovascular events.

The researchers but also stressed that the overall risk was comparatively small. Dr Colin Baigent, lead researcher explained that with this data they now have a complete picture of the effects of COX-2s and NSAIDs. And that it was clear that the risks are small for people who don’t have a history of heart attack or stroke. They said that as these drugs are important for helping people in controlling their pain they should discuss the risks with their physicians and decide whether the risks was acceptable by them. He also added that these studies were still primary and more were needed before they could make any recommendations on their uses.

A spokesperson for Arthritis Care agreed that patients should be left to make the choice: Explaining that millions of people take NSAIDs, and those taking higher doses generally do so because they're in a significant amount of pain she said that by providing them with accurate information would help them in making an informed choice.

Related medicine news :

1. India To Procure 1 Million Doses Of Tamiflu
2. Small Doses Of Radiation Can Help Certain Lung Cancer Patients
3. Polyphenols in Green Tea Cause Liver Damage At High Doses
4. Pre-eclampsia Pronounced With Intake of Vitamins in Large Doses
5. Stronger Doses Fewer Administration for Breast Cancer
6. Even Normal Doses Of Tylenol Could Damage Liver
7. Allergic Individuals Should Carry Two Doses Of EpiPen Says Quebec Coroner
8. Reduced Doses of Medication Beneficial to Preschoolers with ADHD
9. Low Doses of Anti-Depressant May Help PMS
10. Low Doses Of Arsenic Have Broad Impact On Hormone Activity – Says A Researc
11. High Doses of Lithium-Like Drugs May Impair Neuronal Function
Post Your Comments:

(Date:11/27/2015)... ... November 27, 2015 , ... The print component of “Supporting ... Atlanta, Dallas, New York, Minneapolis, South Florida, with a circulation of approximately 250,000 ... through a vast social media strategy and across a network of top news ...
(Date:11/27/2015)... ... ... MPWH, the No.1 Herpes-only dating community in the world, revealed that over 50% of its ... 3.7 billion people under the age of 50 – or 67% of the population - ... estimates of HSV-1 infection . , "The data shocks us highly!" said Michelle Li, ...
(Date:11/27/2015)... Wilmington, DE (PRWEB) , ... November 27, 2015 ... ... a member of the well-respected Microsoft Dynamics SL User Group (MSDSLUG). Recognized as ... is an independent group of Microsoft Dynamics SL software users, partners, industry experts ...
(Date:11/27/2015)... MINNEAPOLIS, Minn. (PRWEB) , ... November 27, 2015 ... ... you start failing. Secura Consultants has prided itself for not only fulfilling the ... best income protection solutions at an affordable price and providing top-tier customer service. ...
(Date:11/27/2015)... Los Angeles, CA (PRWEB) , ... November 27, 2015 , ... ... the Commission on Accreditation of Allied Health Education Programs (CAAHEP) awarded accreditation to its ... exclusive list of CAAHEP accredited colleges, as only one of twelve colleges and universities ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... Research and Markets ( ) has announced ... Outlook to 2019 - Rise in Cardiac Disorders and Growing ... to their offering. Boston ... scientific and others. --> The market ... Boston scientific and others. ...
(Date:11/26/2015)... Nov. 26, 2015 Research and Markets ... the "2016 Future Horizons and Growth Strategies ... Supplier Shares, Country Segment Forecasts, Competitive Intelligence, Emerging ... --> --> This ... the Japanese therapeutic drug monitoring market, including emerging ...
(Date:11/26/2015)... 2015 ... the  "2016 Future Horizons and Growth ... Testing Market: Supplier Shares, Competitive Intelligence, ... --> ) has ... Future Horizons and Growth Strategies in ...
Breaking Medicine Technology: