Navigation Links
Hh Signaling May Play Role In Fat Formation

Mammals and insects might have a lot in common while gaining fat. The hedgehog (Hh) signaling pathway may also have a prominent role when it comes to fat formation in the case of mice and flies, according to a new research. // The research also reveals the effect that genes have on fat storage. The Hh pathway in mammals also decides as to whether adult stem cells are meant for the bone or fat.

The Hh pathway drugs may also be useful for treating conditions like diabetes, obesity, osteoporosis, and lipodystrophy, according to the research. Common traits which are connected with aging may also be explained through the research. As a person ages, he gains weight while his bones become thinner, and this trend may be prevented or reversed with new drugs which stimulate the pathway, contributing towards stronger bones.

The Hh treatment of mouse cells produced lesser fat, in addition to showing signs which are connected to cells which are meant for the bone. The mice that are genetically obese have lower levels of the Hh pathway. The role of the Hh signaling varies from vertebrates and invertebrates. The Hh proteins’ activity can be modulated by small molecules, according to the study, which gives rise to the possibility that drugs aimed at the fat pathway may be in existence already, while more could be made.

The drugs which are capable of manipulating Hh signaling may also serve to treat obesity, disease of altered adiposity, and lipodystrophy. It is also possible that when fat formation is blocked, then other parts of the body like the liver or muscle may experience higher lipid deposits. Even without taking the therapeutic implications of the study into consideration, it has been proved that the Hh plays an important role where fat formation is concerned.


'"/>




Page: 1

Related medicine news :

1. Chemical Signaling Helps Regulate Sensory Map Formation In The Brain
2. Birth Defects Caused By Deficiencies In Cell Signaling Pathway
3. Key Signaling Switch Identified in Allergic Disease
4. Lake Superior in US Losing Ice Cover Fast, Signaling Global Warming
5. The Role Of Calcium In The Formation Of Kidney Stones
6. The Role Of Calcium In The Formation Of Kidney Stones
7. The Role Of Calcium In The Formation Of Kidney Stones
8. Being Obese Could Lead To Kidney Stone Formation
9. Passive Cigarette Smoking Increases Isoprostane Formation
10. Chemical Signaling Helps Regulate Sensory Map Formation In The Brain
11. Mystery behind the Formation of Vertebral Precursors Unraveled
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/24/2017)... ... April 24, 2017 , ... Pitavastatin, a relatively ... it is not known to have significant interactions with antiretroviral therapy (ART). ... cholesterol levels and dampen inflammation in the bloodstream. , While lowering cholesterol and ...
(Date:4/24/2017)... ... 24, 2017 , ... Labs often perform the same operations ... operators and management to assess these processes with a critical eye—particularly in the ... , Created with the help of both internal and external process experts, ...
(Date:4/24/2017)... ... ... “Reflections of God’s Work”: an enlightening collection of life lessons leading each person ... author, Jerri Broglin, a survivor of great loss who gained insight on how to ... those searching for answers, as we are finding the answers that are so deep ...
(Date:4/24/2017)... ... April 24, 2017 , ... ... PA will be attending the 2017 Oral Reconstruction Foundation’s 2017 Symposium on Tissue ... Oral Reconstruction Foundation will present its annual Global Symposium at the Fontainebleau Hotel ...
(Date:4/24/2017)... ... 24, 2017 , ... Anaconda BioMed, a pre-clinical stage medical ... treatment of Acute Ischemic Stroke (AIS), today announced it has appointed Creganna Medical ... towards regulatory and clinical phases. , "This is another important step for Anaconda ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)... R.I. , April 20, 2017  CVS ... CVS), today unveiled a new store design to ... assortment of healthier food, health-focused products and expanded ... store to help customers discover new offerings. Together ... the next evolution of the customer experience at ...
(Date:4/20/2017)... , April 20, 2017  AbbVie (NYSE: ABBV), ... percent (n=145/146) of chronic hepatitis C virus (HCV) ... or 6 and compensated cirrhosis (Child-Pugh A) achieved ... 12 ) with its investigational, pan-genotypic regimen of ... were seen following 12 weeks of G/P treatment ...
(Date:4/20/2017)... Eyevensys, a private biotechnology company ... expression technology that enables the safe, local, sustained production ... wide range of ophthalmic diseases, announces it has received ... Agency (MHRA) to advance its technology into clinical development. ... The EyeCET ...
Breaking Medicine Technology: