Navigation Links
Hemangioblasts Aiding Eye Damage Repair

Massachusetts-based company Advanced Cell Technology, is obviously thrilled with their landmark discovery of hemangioblasts or stem cells that repair arteries and regenerate blood.

According to the company,the stem cells made from human embryos can proceed on to hearts and arteries of mice and rats, and appear to start repairs. ACT claims to have devised a straightforward way to make blood vessel precursor cells out of the stem cells. The company plans to test them in humans.

Says Dr. Robert Lanza, vice president of research and scientific development at ACT :"We figured out how to produce literally billions of so-called 'hemangioblasts' -- the mythical cell in the embryo that gives rise to our entire blood and immune system as well as to the blood vessels in our body. "We've also tested these cells in animals for the first time, and it turns out that they have incredible reparative potential, he added.

Embryonic stem cells are the ultimate master cell of the body, giving rise to all of the tissues and organs. The use of human embryonic stem cells is controversial because many people oppose destroying the embryo or in effect, an unborn child. The U.S. Congress has passed several bills that would expand federal funding of human embryonic stem cell research but President George Bush vetoed one and has said he will veto any more. Yet, companies working with private funding, such as the over-the-counter listed ACT, may do as they please.

Working with embryonic stem cells is not easy. For medical uses, researchers would like to partly differentiate them -start them down the road toward becoming a specific cell or tissue type. Another roadblock is that many of the current batches, or lines, of stem cells must be grown in a serum culture taken from animal blood. This can contaminate them with viruses.

Writing in the journal Nature Methods, Lanza's team said they found a way to grow and differentiate human embryonic stem cells without using culture. They directed the stem cells into becoming what they believe are hemangioblasts, the blood vessel precursor cells, although other teams will have to replicate this for it to be accepted.

Says Lanza: "When injected into the bloodstream, they homed to the other side of the body and repaired damaged vasculature within 24 to 48 hours. "For example, we injected the cells into mice with damaged retinas due to diabetes or other eye injury. The cells migrated to the injured eye, and incorporated and lit-up the entire damaged vasculature. The cells are really smart, and amazingly, knew not to do anything in uninjured eyes. "The cells also showed remarkable reparative capacity in animals with heart attacks and ischemic (blocked by a blood clot) limbs. The cells reduce the mortality rate by 50 percent after a massive heart attack. "If the same thing works in humans (these would be the same human cells we would probably use), you might be able to prevent patients from having legs and other limbs amputated by simply injecting some cells, Lanza stresses.

William Caldwell, chairman and chief executive officer of Advanced Cell Technology, announcing that the company wants to test the cells in people has asked the Food and Drug Administration for permission to do so by the end of next year.

"We also have studies underway indicating that the cells can also considerably accelerate wound healing, repair lung damage, and can even generate unlimited amounts of red blood cells for transfusion," Lanza states.


'"/>




Related medicine news :

1. Hemangioblasts New Tool Of Stem Cell Technology
2. Evidence Links Protein Damage to Neurodegenerative diseases like Parkinsons and Alzheimers
3. Paracetamol May Cause Live Damage Warns Consumer Education and Research Centre
4. Arthritis Drug May Cause Liver Damage
5. Damage to arteries from injury can be avoided with carbon monoxide
6. Epilepsy Drug Helps Diabetic Nerve Damage
7. Different Sun Rays, Different Damage
8. Drug That Is Found To Reduce Heart Damage from Chemo
9. Cooling Can Reduce The Risk Of Brain Damage In Oxygen Deprived Newborns
10. Damaged Heart Rejuvenated By Stem Cells
11. Traffic Smoke May Damage DNA
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/19/2017)... ... February 19, 2017 , ... Braun Industries will be participating as an ... event will take place February 23-25, 2017 at the Calvin L. Rampton Salt Palace ... with three new ambulances on display. , “JEMS is a leader ...
(Date:2/19/2017)... ... 2017 , ... Orbita, Inc., a leading provider ... Healthwise ® at HIMSS 2017 to showcase a breakthrough in remote ... technology and services, will demonstrate a voice-powered knowedge assistant based on Orbita ...
(Date:2/18/2017)... ... ... Butler Mobility invited Ken Matthews to visit its manufacturing facility and showroom to ... with the safety and reliability of the Stannah Stairlift as well as with the ... by Ken Matthews can be heard on News Radio WHP 580 weekdays from 3:00 ...
(Date:2/18/2017)... ... February 18, 2017 , ... ProParagraph ... Pixel Film Studios ’ ProParagraph Fashion Volume 2 for all multi-line FCPX project ... Users can pick and choose from hand-crafted trend-setting designs with smooth animations ...
(Date:2/17/2017)... Murfreesboro, TN (PRWEB) , ... February 17, 2017 ... ... EHR mobility has not kept pace. Enovate Medical has introduced an innovative workstation ... 20 years of supporting nurses, the Encore Mobile EHR Workstation offers a lightweight, ...
Breaking Medicine News(10 mins):
(Date:2/17/2017)... AMSTERDAM , Feb. 17, ... connected health offerings at the  ...  (NYSE: PHG,AEX: PHIA), a global ... a broad range of population ... personal health solutions, fully integrated in a ...
(Date:2/16/2017)... 2017 Absorption Systems, a global leader in ... pleased to announce that its Chief Operating Officer, ... winner of the 2017 Executive Management Award. The award ... driven executives for their creative management vision, leadership philosophy, ... and celebration is on March 8, 2017 at the ...
(Date:2/16/2017)... , Feb. 16, 2017 The global preparative ... 7.88 billion by 2021 from USD 5.49 billion in ... On the basis of type, the preparative and process ... chromatography. In 2016, the process chromatography segment is expected ... preparative and process chromatography. Growth in this segment can ...
Breaking Medicine Technology: