Navigation Links
Heart Drug has grave side effects

According to researchers, a drug commonly used for short-term treatment of worsening heart failure in hospitalized patients may cause dangerously low blood pressure and abnormal heart rhythms. //The findings suggest that the drug, milrinone, should be reserved for patients who do not respond to other medication, said Dr. Mihai Gheorghiade of Northwestern University.

According to Gheorghiade, the study is one of the few to compare a placebo with a drug for worsening heart failure, a condition that sends about 1 million Americans to the hospital each year. Despite the poor results, it shows that such studies can and should be done on similar drugs.

An accompanying editorial says the use of other drugs commonly used in worsening heart failure, dopamine and dobutamine, should be reconsidered given the milrinone findings, since all three drugs work similarly to strengthen the heartbeat.

Heart failure, in which the heart gradually loses its ability to pump blood efficiently, affects nearly 5 million Americans. The condition may be chronic, but patients can develop severe attacks of breathing difficulty that require hospitalization.

Dr. Ann Bolger, an American Heart Association spokeswoman, said patients studied were generally less sick than those who typically would be given milrinone. The study shows ``there really isn't any advantage'' to giving milrinone to patients who are not acutely ill, Bolger said.

Sanofi-Synthelabo Inc., which markets milrinone in the United States, funded the study. The company's Web site warns that the drug may cause irregular heartbeats, and says milrinone should be stopped if blood pressure falls too low. It also says that the drug may not be safe or effective when given for longer than 48 hours, and that long-term oral treatment has been linked with an increased risk of hospitalization and death.

Another JAMA study shows favorable results for a newer drug called Natrecor, app roved last year for worsening heart failure. Known chemically as nesiritide, the drug improved breathing and blood flow, and appeared to work more quickly than intravenous nitroglycerin.

Dr. Michael Cuffe, a Duke University cardiologist who helped lead the milrinone study, said the research looked at how patients fared over the longer term, unlike the research that led to government approval of the drug. The study involved 949 patients given either a dummy drug or a 48-hour milrinone infusion.


'"/>




Related medicine news :

1. One in Three Heart Attack Patients Have No Chest Pains
2. Epileptic Seizures Can Be Due to Heart Problem
3. Bypass Heart Surgery Performed Without General Anesthesia
4. New CPR Guidelines issued by Heart Association
5. White Cells Count Can Predict Heart Attack Death Risk
6. Vitamins-The answer to Heart Disease?
7. Fight Heart disease and Pain with Meditation
8. Heart disease in the newborn is related to maternal malnutrition
9. New drug to treat Heart Attack and damaged tissue
10. Heart disease threat starts early in life for Diabetics
11. Mechanical Heart
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/26/2017)... ... 26, 2017 , ... Amir Qureshi, MD is the first physician in Arkansas ... stimulation system. The Nuvectra™ Algovita SCS System has been FDA approved as a treatment ... in Arkansas to introduce the most powerful SCS system and the only stretchable lead ...
(Date:5/26/2017)... MA (PRWEB) , ... May 26, 2017 , ... On ... Act (AHCA), which narrowly passed the U.S. House on May 4, would result in ... be expected under continued implementation of the 2010 Patient Protection and Affordable Care Act ...
(Date:5/26/2017)... ... May 26, 2017 , ... Dr. Alex Rabinovich, a highly-skilled ... a new, informational blog post on insurance options. If a Bay Area patient has ... help save time and money. Visiting an in-network provider for a second opinion can ...
(Date:5/26/2017)... ... 2017 , ... “Cactus Jack: Against All Odds”: the story of Coach Cactus ... Against All Odds” is the creation of published author, Walter Hubbard, a retired wildlife ... Carlisle’s third child Jane. Walter. Walter and Jane have three adult children and ...
(Date:5/24/2017)... , ... May 24, 2017 , ... Altec ... participation in nVerge 2017 – a one-day technology conference in San Diego, CA. ... solution, which allows users to fully utilize and enhance their Sage ERP solutions by ...
Breaking Medicine News(10 mins):
(Date:5/10/2017)... -- Global Health Intelligence (GHI), the leading healthcare ... published its 2017 ranking of the Best-Equipped Hospitals in ... analysis from GHI,s hospitals database for Latin America , ... The GHI database covers 86% of the hospitals in ... points for each institution in key areas such as beds, ...
(Date:5/9/2017)... Zimmer Biomet Holdings, Inc. (NYSE and SIX: ... it has earned a spot on Forbes, ... was ranked among 500 U.S. employers as well as ... and Services. The annual Forbes ... survey of over 30,000 employees across 25 industries. The ...
(Date:5/8/2017)... NEW YORK , May 8, 2017 ... in the transition from fee for service reimbursement. Black ... April 2017. 1.       The Market for ... 77% of physician practices with 3 or ... Compliance Technology Solutions by Q4. "Given the magnitude of ...
Breaking Medicine Technology: