Navigation Links
Harmful Effects Of Glucocorticoids On Newborns Owing To Prenatal Exposure

It has been found by the scientists from the University of Edinburgh in UK that when nonhuman primate African vervet monkeys (Chloroceus aethiops) //in their prenatal stage were exposed to glucocorticoids it had a life long destabilizing effect on cardiovascular, metabolic, and neuroendocrine function.

Glucocorticoids are still widely used in obstetric practice. So, Jonathan Seckl and colleagues set out to determine the relevance to human pregnancy of rodent and nonprimate data indicating that prenatal exposure to glucocorticoids (through either the administration of dexamethasone or severe maternal stress) has long-lasting deleterious effects. In the study, which appears online on March 22 in advance of publication in the April print issue of the Journal of Clinical Investigation, they show that although the birth weight of offspring born to nonhuman primate African vervet monkeys treated with dexamethasone from mid-gestation onward did not differ from that of offspring born to untreated animals, the high levels of prenatal dexamethasone impaired postnatal growth, impaired glucose-insulin homeostasis, increased blood pressure 12 months after birth, and increased the production of cortisol in response to mild stress. These data suggest that both repeated glucocorticoid therapy and severe maternal stress late in gestation are likely to have long-term deleterious effects on developing human fetuses.

Source-Eurekalert
JYT
'"/>




Page: 1

Related medicine news :

1. More Elderly Take Inappropriate and Harmful Medications
2. Healthy Medicine Or Harmful Intoxicant?
3. Antidepressants Harmful for Kids
4. The Harmful Effects Of Cigarette Smoke
5. Antidepressants Late In Pregnancy Harmful to Unborn Baby
6. The Harmful Effects Of Stress in Young Adults
7. Yet Another Harmful Consequence Of Smoking
8. Understanding The Harmful Effects Of Radiation Exposure
9. The Harmful Effects Of Secondhand Smoke
10. Harmful chemicals change the genetic response to hormone estrogen
11. Intake of Vitamin E Supplements During Pregnancy May be Harmful
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/5/2016)... (PRWEB) , ... February 05, 2016 , ... ... ranked #3 in the 2015 Best in KLAS: Software & Services for HIT ... annual Best in KLAS report independently ranks vendor performance by healthcare executives, managers ...
(Date:2/5/2016)... ... ... Stuart Bentkover, MD, FACS is thrilled to announce the arrival ... tattoo removal today, Dr. Bentkover is the only doctor in Central Massachusetts to offer ... been approved by the Food and Drug Administration (FDA) as a safe and efficient ...
(Date:2/5/2016)... ... February 05, 2016 , ... In sleep, when the defenses of ... A hallmark feature of patients with eating disorders is significant self-criticism, and consequently these ... and obsessions are regarded as maladaptive means for coping with this unease, but also ...
(Date:2/5/2016)... ... February 05, 2016 , ... On ... Rare Diseases, a continuing medical education (CME) event presented by the Association for ... kind—and a first for ACCORD, whose mission is to provide education, tools, and ...
(Date:2/5/2016)... ... February 05, 2016 , ... –This week, Atascadero water heater company ... tankless water heater. To view the report, click here or see below. ... each has their pros and cons, the type chosen is almost entirely up to ...
Breaking Medicine News(10 mins):
(Date:2/5/2016)... Feb. 5, 2016 Aethlon Medical, Inc. (Nasdaq: ... and CEO, will be presenting at Source Capital Group,s 2016 ... NY at 2:15 p.m. ET on Wednesday, February ... Panel discussion taking place at 3:15 p.m. ET. ... one hour after the conclusion of the live event. The ...
(Date:2/5/2016)... -- Dehaier Medical Systems Ltd. (Nasdaq: DHRM ... markets and sells medical devices and wearable sleep ... and international markets, today announced its corporate and ... Company,s resources to develop its mobile health business, ... more on its major businesses. As of this ...
(Date:2/5/2016)...  Henry Schein, Inc. (NASDAQ: HSIC ), the world,s ... office-based dental, animal health and medical practitioners, announced today ... a majority ownership interest in Dental Cremer S.A., a ... Brazil . --> ... the dental distribution business of Cremer S.A. With 2015 ...
Breaking Medicine Technology: