Navigation Links
Harmful Effects Of Glucocorticoids On Newborns Owing To Prenatal Exposure

It has been found by the scientists from the University of Edinburgh in UK that when nonhuman primate African vervet monkeys (Chloroceus aethiops) //in their prenatal stage were exposed to glucocorticoids it had a life long destabilizing effect on cardiovascular, metabolic, and neuroendocrine function.

Glucocorticoids are still widely used in obstetric practice. So, Jonathan Seckl and colleagues set out to determine the relevance to human pregnancy of rodent and nonprimate data indicating that prenatal exposure to glucocorticoids (through either the administration of dexamethasone or severe maternal stress) has long-lasting deleterious effects. In the study, which appears online on March 22 in advance of publication in the April print issue of the Journal of Clinical Investigation, they show that although the birth weight of offspring born to nonhuman primate African vervet monkeys treated with dexamethasone from mid-gestation onward did not differ from that of offspring born to untreated animals, the high levels of prenatal dexamethasone impaired postnatal growth, impaired glucose-insulin homeostasis, increased blood pressure 12 months after birth, and increased the production of cortisol in response to mild stress. These data suggest that both repeated glucocorticoid therapy and severe maternal stress late in gestation are likely to have long-term deleterious effects on developing human fetuses.

Source-Eurekalert
JYT
'"/>




Page: 1

Related medicine news :

1. More Elderly Take Inappropriate and Harmful Medications
2. Healthy Medicine Or Harmful Intoxicant?
3. Antidepressants Harmful for Kids
4. The Harmful Effects Of Cigarette Smoke
5. Antidepressants Late In Pregnancy Harmful to Unborn Baby
6. The Harmful Effects Of Stress in Young Adults
7. Yet Another Harmful Consequence Of Smoking
8. Understanding The Harmful Effects Of Radiation Exposure
9. The Harmful Effects Of Secondhand Smoke
10. Harmful chemicals change the genetic response to hormone estrogen
11. Intake of Vitamin E Supplements During Pregnancy May be Harmful
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/8/2016)... ... 2016 , ... ZyDoc , a New York-based medical ... Capture Methods for Input to Electronic Health Records: A Comparative Usability Study” has ... usability study demonstrate that a dictation-based method (“NLP Entry”) using ZyDoc’s MediSapien™ natural ...
(Date:12/8/2016)... ... 08, 2016 , ... David J. Dykeman , Ginger Pigott , ... will speak at DeviceTalks West, Dec. 12, 2016, at the Fairmont Newport Beach in ... the firm’s global Life Sciences & Medical Technology Group have been featured speakers at ...
(Date:12/8/2016)... ... 08, 2016 , ... STATEN ISLAND, N.Y., Nov. 24, 2016 ... the highest standards of trauma, maternity, cancer and chronic obstructive pulmonary disease (COPD) ... Dr. Daniel Messina. , Among the recognitions, the American College of Surgeons' (ACS) ...
(Date:12/8/2016)... California (PRWEB) , ... December 08, 2016 , ... ... has raised an $18M Series B led by Canvas Ventures . Other investors ... capital to scale its mobile platform to serve more consumers who are managing ...
(Date:12/8/2016)... ... December 08, 2016 , ... Coppin Insurance Agency, an insurance and financial ... around the Cape Coral area, is embarking on a charity drive with the goal ... , The Harry Chapin Food Bank of Southwest Florida works to provide fresh and ...
Breaking Medicine News(10 mins):
(Date:12/8/2016)... 2016  Hanson Research, an innovative leader in ... diffusion testing instruments for the pharmaceutical industry, announced ... Inc. ("Teledyne"). The move is designed to deepen ... instruments, as well as expand resources for further ... and services. Logo - http://photos.prnewswire.com/prnh/20161208/446988LOGO ...
(Date:12/8/2016)... FRANCISCO , Dec. 8, 2016 ... today announced that it has closed a $23 ... McKesson Ventures and OrbiMed. The company seeks to ... time physicians spend on mandated EHR documentation. The ... scribe service that frees doctors from 3 hours ...
(Date:12/8/2016)... LITTLE FALLS, N.J., Dec. 8, 2016 CANTEL MEDICAL ... net income of $18,800,000, or $0.45 per diluted share, on ... the first quarter ended October 31, 2016. This compares with ... sales of $153,779,000 for the first quarter ended October 31, ... the first quarter ended October 31, 2016 to $21,323,000, or ...
Breaking Medicine Technology: