Navigation Links
Harmful Effects Of Glucocorticoids On Newborns Owing To Prenatal Exposure

It has been found by the scientists from the University of Edinburgh in UK that when nonhuman primate African vervet monkeys (Chloroceus aethiops) //in their prenatal stage were exposed to glucocorticoids it had a life long destabilizing effect on cardiovascular, metabolic, and neuroendocrine function.

Glucocorticoids are still widely used in obstetric practice. So, Jonathan Seckl and colleagues set out to determine the relevance to human pregnancy of rodent and nonprimate data indicating that prenatal exposure to glucocorticoids (through either the administration of dexamethasone or severe maternal stress) has long-lasting deleterious effects. In the study, which appears online on March 22 in advance of publication in the April print issue of the Journal of Clinical Investigation, they show that although the birth weight of offspring born to nonhuman primate African vervet monkeys treated with dexamethasone from mid-gestation onward did not differ from that of offspring born to untreated animals, the high levels of prenatal dexamethasone impaired postnatal growth, impaired glucose-insulin homeostasis, increased blood pressure 12 months after birth, and increased the production of cortisol in response to mild stress. These data suggest that both repeated glucocorticoid therapy and severe maternal stress late in gestation are likely to have long-term deleterious effects on developing human fetuses.

Source-Eurekalert
JYT
'"/>




Page: 1

Related medicine news :

1. More Elderly Take Inappropriate and Harmful Medications
2. Healthy Medicine Or Harmful Intoxicant?
3. Antidepressants Harmful for Kids
4. The Harmful Effects Of Cigarette Smoke
5. Antidepressants Late In Pregnancy Harmful to Unborn Baby
6. The Harmful Effects Of Stress in Young Adults
7. Yet Another Harmful Consequence Of Smoking
8. Understanding The Harmful Effects Of Radiation Exposure
9. The Harmful Effects Of Secondhand Smoke
10. Harmful chemicals change the genetic response to hormone estrogen
11. Intake of Vitamin E Supplements During Pregnancy May be Harmful
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/24/2017)... ... ... The weather is heating up and the days are getting longer, providing the ... the summer months provide more than warmer temperatures that are perfect for BBQ’s and ... from direct exposure to the sun. When it comes to the security of homes ...
(Date:6/23/2017)... ... June 23, 2017 , ... The ... launch of Care Management Alerts and Dashboards, an innovative new service enabling healthcare ... , RIQI’s Care Management Alerts and Dashboards provide near real-time data about patients ...
(Date:6/23/2017)... CA (PRWEB) , ... June 23, 2017 , ... By ... earned its ninth consecutive four-star rating from premier online charity evaluator, Charity Navigator, validating ... the top 1% of all charities reviewed by Charity Navigator and earns ANRF a ...
(Date:6/23/2017)... ... ... show evidence that carotenoids and antioxidants derived either from the diet or from supplements ... often do ophthalmologists and optometrists in Sweden recommend the use of nutritional supplements, changes ... of AMD? A study published recently in Dove Medical Press journal, ...
(Date:6/23/2017)... , ... June 23, 2017 , ... ... surgeon practicing in Newburgh, New York, has recently begun offering three new minimally ... offering the best cutting-edge procedures and reducing downtime, Dr. Rubinstein is excited to ...
Breaking Medicine News(10 mins):
(Date:6/14/2017)... June 14, 2017  ivWatch LLC, a medical device ... intravenous (IV) therapy, is pleased to announce it was ... Nonsurgical Hospital Supplies and Equipment at the 2017 Medical ... the medtech industry. The award was presented by Medical ... Javits Center in New York ...
(Date:6/11/2017)...  Eli Lilly and Company (NYSE: LLY ) ... of galcanezumab, an investigational treatment for the prevention of ... key secondary endpoints for galcanezumab compared to placebo at ... EVOLVE-2 and REGAIN) will be presented today at the ... Boston . "The detailed ...
(Date:6/8/2017)...   Responding to Heath Ledger,s father,s recent ... singer Chris Cornell in May, the mental health ... free online psychiatric drug side effects search ... psychotropic drug risks. The father of the ... accidental overdose, has called for tighter rules on prescription drugs. ...
Breaking Medicine Technology: