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HIV Drug Combo can Boost Immune Marker in Long-term Patients: Study

rs, though, if patients continue to respond well to the drugs and can keep their HIV count to below 50 copies per microlitre, the authors warn.

CD4 cells are frontline guardians of the immune system and their levels are closely watched barometers of a patient's ability to fight off opportunistic disease and death.

Previous research in this field has been more pessimistic, suggesting that CD4 counts tend to plateau after several years of treatment.

But those studies used less strict criteria for determining whether the drugs were working.

Their benchmark was a viral load -- the number of AIDS viruses in the blood -- of 1,000 and 400 copies per microlitre, whereas the new study sets a far tougher standard of 50 copies or less.

The paper is published by The Lancet ahead of a meeting in Sydney from Sunday to July 25 of the International AIDS Society, which will focus especially on HIV treatment.


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