Navigation Links
HIV Becomes More Infectious Due To Human Immune-system Protein

Scientists have found that the human form of immune-system protein, cyclophilin A, changes the shape of HIV particles to make them more infectious//.

Cyclophilin A is found in HIV-1 when the virus attacks human and monkey cells, researchers at University College of London said.

The researchers, who infected cells from Old World monkeys with HIV-1, found that cyclophilin A changed the shape of the virus particles, reports the latest issue of New Scientist.

This trick made the virus vulnerable to attack by TRIM5-alpha, part of the monkeys' innate immune system, which stops it in its tracks, but it was a different story when they infected human cells with HIV-1.

They found that the human form of cyclophilin A still changed the shape of the virus particles, but only to make them more infectious.

HIV-1 has the ability to tolerate cyclophilin A activity when it gets into human cells and the virus is using cyclophilin A to help it replicate, leading researcher Greg Towers was quoted as saying.

The changes to HIV-1 that allowed it to infect human cells might have occurred long before it actually crossed over to humans, according to Towers.

He said the researchers were a step closer to understanding how the innate immune system and HIV work together, and to discovering the interactions that allow the virus to cross the species barrier.

"The more we understand, the more likely we are going to be able to design improved therapeutics," Towers said.

--Edited IANS
'"/>




Page: 1

Related medicine news :

1. Inhuman Error: Medicine Becomes Poison, Causing Death
2. Nature’s Bounty ,Seaweed, Becomes A Blessing For Diabetes Patient
3. Medical Education Becomes Dearer In Scotland
4. British Psychiatrist At 62 Becomes The Countries Oldest Mother
5. ‘Braveheart’- Woman Becomes First to Climb Mountains After Heart Transplat
6. Patents: Appellate Board Becomes Functional
7. Transmission Of Infectious Disease On Planes Analyzed
8. Sex Played A Vital Role For Evolution Of Infectious Diseases
9. Systemic Corticosteroid Therapy can be used for treating all types of Infectious Mononucleosis
10. Infectious Diseases of the Wild to grow
11. Infectious Diseases Reduced in China
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/8/2016)... ... December 08, 2016 , ... The Florida Hospital ... and Hyperbaric Medical Society (UHMS), the leading authority in hyperbaric medicine. This accreditation ... a few hospitals and facilities have earned this distinction. This is the second ...
(Date:12/8/2016)... ... 2016 , ... Mirixa Corporation , a leading healthcare ... patient care services, has announced the promotions of Karen Litsinger to senior vice ... sales. , Litsinger joined Mirixa in 2008 after serving as a partner ...
(Date:12/8/2016)... (PRWEB) , ... December 08, 2016 , ... ... modes of access for customers and employees that are both engaging and easy ... with Service Smart Technology, the software company revealed today its plans to roll ...
(Date:12/8/2016)... ... , ... California Senate Bill (SB) 863, signed into law in 2012, may ... 2014, according to CompScope™ Medical Benchmarks for California, 17th Edition , a study ... medical payments per claim in California decreased 4 percent in 2013 and then 3 ...
(Date:12/8/2016)... ... December 08, 2016 , ... ... planning services from offices headquartered in Hamilton County, is embarking on a charity ... LuvFurMutts specializes in finding new homes for orphaned or neglected senior dogs in ...
Breaking Medicine News(10 mins):
(Date:12/8/2016)... LAVAL, Quebec , Dec. 8, 2016 /PRNewswire/ ... and TSX: VRX) ("Valeant") today announced positive ... vehicle-controlled clinical study to assess the safety and ... in the treatment of plaque psoriasis. ... adult subjects with moderate to severe psoriasis, IDP-118 ...
(Date:12/8/2016)... -- Mederi Therapeutics Inc . hat die behördliche Zulassung durch die ... Refluxerkrankung (GERD) – in China angekündigt. ... ... Live Stretta procedure performed and broadcast during the ... at Wuhan Union Hospital ...
(Date:12/8/2016)... , Dec. 8, 2016  Boehringer Ingelheim announced today ... Equality Index (CEI). This is the ninth time that ... designated as a Best Place to Work for LGBT ... CEI is a national benchmarking report on corporate policies ... bisexual and transgender (LGBT) employees. "We ...
Breaking Medicine Technology: