Navigation Links
HIV Becomes More Infectious Due To Human Immune-system Protein

Scientists have found that the human form of immune-system protein, cyclophilin A, changes the shape of HIV particles to make them more infectious//.

Cyclophilin A is found in HIV-1 when the virus attacks human and monkey cells, researchers at University College of London said.

The researchers, who infected cells from Old World monkeys with HIV-1, found that cyclophilin A changed the shape of the virus particles, reports the latest issue of New Scientist.

This trick made the virus vulnerable to attack by TRIM5-alpha, part of the monkeys' innate immune system, which stops it in its tracks, but it was a different story when they infected human cells with HIV-1.

They found that the human form of cyclophilin A still changed the shape of the virus particles, but only to make them more infectious.

HIV-1 has the ability to tolerate cyclophilin A activity when it gets into human cells and the virus is using cyclophilin A to help it replicate, leading researcher Greg Towers was quoted as saying.

The changes to HIV-1 that allowed it to infect human cells might have occurred long before it actually crossed over to humans, according to Towers.

He said the researchers were a step closer to understanding how the innate immune system and HIV work together, and to discovering the interactions that allow the virus to cross the species barrier.

"The more we understand, the more likely we are going to be able to design improved therapeutics," Towers said.

--Edited IANS
'"/>




Page: 1

Related medicine news :

1. Inhuman Error: Medicine Becomes Poison, Causing Death
2. Nature’s Bounty ,Seaweed, Becomes A Blessing For Diabetes Patient
3. Medical Education Becomes Dearer In Scotland
4. British Psychiatrist At 62 Becomes The Countries Oldest Mother
5. ‘Braveheart’- Woman Becomes First to Climb Mountains After Heart Transplat
6. Patents: Appellate Board Becomes Functional
7. Transmission Of Infectious Disease On Planes Analyzed
8. Sex Played A Vital Role For Evolution Of Infectious Diseases
9. Systemic Corticosteroid Therapy can be used for treating all types of Infectious Mononucleosis
10. Infectious Diseases of the Wild to grow
11. Infectious Diseases Reduced in China
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... 2017 , ... The International Association of Eating Disorders Professionals ... the field of eating disorders, announces the opening of early registration for the ... at the Omni Resort at ChampionsGate. , The annual iaedp™ Symposium ...
(Date:10/13/2017)... ... October 13, 2017 , ... Lori R. Somekh, founder ... of ElderCounsel, a national organization of elder law and special needs planning attorneys. “Membership ... rules. It also provides a forum to network with elder law attorneys nationwide,” said ...
(Date:10/13/2017)... , ... October 13, 2017 , ... The Visiting Nurse ... Market. Featuring a collection of specialty vendors and unique items from across the nation, ... quality-focused health and wellness services offered by the VNA. The boutique will be ...
(Date:10/13/2017)... , ... October 13, 2017 , ... Yisrayl Hawkins, Pastor ... that explains one of the most popular and least understood books in the Holy ... and puzzling descriptions that have baffled scholars for centuries. Many have tossed it off ...
(Date:10/13/2017)... ... ... “The Journey: From the Mountains to the Mission Field”: the story of ... Philippines. “The Journey: From the Mountains to the Mission Field” is the creation of ... taught all ages and currently teaches a class of ladies at her church, which ...
Breaking Medicine News(10 mins):
(Date:9/28/2017)... , Sept. 28, 2017 Cohen Veterans Bioscience ... the use of wearable and home sensors for real-time ... Early Signal Foundation, a nonprofit organization focused on disruptive ... provide an affordable analytical system to record and integrate ... ...
(Date:9/23/2017)... HORSHAM, Pa. , Sept. 22, 2017 ... received a complete response letter from the U.S. Food ... (BLA) seeking approval of sirukumab for the treatment of ... response letter indicates additional clinical data are needed to ... of moderately to severely active RA. ...
(Date:9/18/2017)... Mich. , Sept. 18, 2017  PMD Healthcare ... Specialty Pharmacy of Kalamazoo, Mich. , ... hub service that expedites and streamlines patient and provider ... PD 2.0, and wellness management services.  ... device used to measure lung function for a variety ...
Breaking Medicine Technology: