Navigation Links
HIV Becomes More Infectious Due To Human Immune-system Protein

Scientists have found that the human form of immune-system protein, cyclophilin A, changes the shape of HIV particles to make them more infectious//.

Cyclophilin A is found in HIV-1 when the virus attacks human and monkey cells, researchers at University College of London said.

The researchers, who infected cells from Old World monkeys with HIV-1, found that cyclophilin A changed the shape of the virus particles, reports the latest issue of New Scientist.

This trick made the virus vulnerable to attack by TRIM5-alpha, part of the monkeys' innate immune system, which stops it in its tracks, but it was a different story when they infected human cells with HIV-1.

They found that the human form of cyclophilin A still changed the shape of the virus particles, but only to make them more infectious.

HIV-1 has the ability to tolerate cyclophilin A activity when it gets into human cells and the virus is using cyclophilin A to help it replicate, leading researcher Greg Towers was quoted as saying.

The changes to HIV-1 that allowed it to infect human cells might have occurred long before it actually crossed over to humans, according to Towers.

He said the researchers were a step closer to understanding how the innate immune system and HIV work together, and to discovering the interactions that allow the virus to cross the species barrier.

"The more we understand, the more likely we are going to be able to design improved therapeutics," Towers said.

--Edited IANS
'"/>




Page: 1

Related medicine news :

1. Inhuman Error: Medicine Becomes Poison, Causing Death
2. Nature’s Bounty ,Seaweed, Becomes A Blessing For Diabetes Patient
3. Medical Education Becomes Dearer In Scotland
4. British Psychiatrist At 62 Becomes The Countries Oldest Mother
5. ‘Braveheart’- Woman Becomes First to Climb Mountains After Heart Transplat
6. Patents: Appellate Board Becomes Functional
7. Transmission Of Infectious Disease On Planes Analyzed
8. Sex Played A Vital Role For Evolution Of Infectious Diseases
9. Systemic Corticosteroid Therapy can be used for treating all types of Infectious Mononucleosis
10. Infectious Diseases of the Wild to grow
11. Infectious Diseases Reduced in China
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/5/2016)... , ... May 05, 2016 ... ... Director 703.462.0658, ctellez(at)msnva.org , The Medical Society of Northern Virginia, Announces ... patients , The Medical Society of Northern Virginia (MSNVA) launches DoctorsTelemed?, a ...
(Date:5/5/2016)... (PRWEB) , ... May 05, 2016 , ... Nepenthe Laboratory ... Riverbend Elementary School last week to raise non-perishable food item donations for Food for ... Nose Day” hosted on NBC. , “The goal of the assembly was to create ...
(Date:5/5/2016)... ... May 05, 2016 , ... Is the part in your ... just a few days away, it’s a good opportunity to raise awareness about a ... American Academy of Dermatology, 40% of women experience hair loss or ‘thinning’ by the ...
(Date:5/5/2016)... Levittown, NY (PRWEB) , ... May 05, 2016 , ... ... the community with their unique approach to dentistry. Dental365 was established with the ... King Kullen Shopping Center, Dental365 gives patients high-quality, affordable dentistry while offering routine and ...
(Date:5/4/2016)... MD (PRWEB) , ... May 05, 2016 , ... The ... directions. High impact injuries like falls, or traffic accidents can cause the talus bone ... (AVN)—the death of the bone. In a first-of-its-kind procedure using 3D printing technology, internationally ...
Breaking Medicine News(10 mins):
(Date:5/3/2016)... CITY, Mo. , May 3, 2016 /PRNewswire/ ... Kansas Medical Center,s Institute for Advancing Medical Innovation ... and commercialize new drugs, diagnostics and medical devices. ... provides BioNovus Innovations with rights to license, develop ... "This partnership represents ...
(Date:5/3/2016)... , May 3, 2016  As a teenager, an ... rheumatic fever, which damaged his heart. He continued enjoying ... by June 2013, Shepherd,s heart was giving out and ... On June 20, 2013, the Mesa, Arizona ... Heart (TAH-t). Like a heart transplant, the SynCardia TAH-t ...
(Date:5/3/2016)...  While you may be familiar with watching a film or TV show in high definition, ... 8MP in the Medical Industry.  Ampronix  is a renowned authorized reseller of the medical industry,s ... - http://photos.prnewswire.com/prnh/20160502/362730 ... ... ...
Breaking Medicine Technology: