( to middle age growth hormone productio...)Growth Hormone Stimulants help to Combat Aging Symptoms,Health

to middle age, growth hormone production begins to taper off. Many of the effects of aging – increased abdominal fat, reduced muscle mass, and decreased physical function – look very similar to the symptoms of growth hormone deficiency in younger people. As those aging effects set in, many older adults find it difficult to care for themselves, and they lose quality of life and often turn to long-term care.

‘If we had something that could reduce that drop-off in physical function, we could improve the quality of life for older adults, and help cut the cost burden of long-term care,’ explained Merriam. ‘What we'd like to do is take the steep curve of physical function decreasing with age, and make that a much shallower decline or even a plateau, so people will retain more physical mobility and strength as they age instead of deteriorating.’

Researchers studying the aging process believe that growth hormone and IGF-1 may be two of the key compounds that regulate the effects of aging, and that stimulating production of the hormones could help stave off those effects. Other studies have shown that treatments can increase the levels of growth hormone and IGF-1, and can help improve a patient's body composition. However, this study is the first to show not just a stabilization of physical function, but an improvement.

‘This is a proof of concept that GHS can help with body composition and physical function,’ Merriam said. ‘These are very encouraging results, and we should examine further whether GHS can help in the long term to mitigate some of the negative effects of aging.’ He added, however, that many steps remain to determine whether this concept could be turned into an effective and safe treatment. The GHS used in the study was discovered and developed by Pfizer Global Research and Development, and is only available for research purposes, not as a prescription or over-the-counter drug.

In addition to the University of Washington
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