Navigation Links
Green Tea and COX-2 Inhibitors Combine to Slow Growth of Prostate Cancer

lementary agents,” Mukhtar said. “Our studies showed that the additive effect of green tea enables us to utilize the cancer-fighting abilities of COX-2 inhibitors, but at lower, safer doses.”

In this latest research, Mukhtar and his colleagues looked at the effects of the two substances on cultured human prostate cancer cells. Alone, both EGCG and NS-398, a COX-2 inhibitor similar to celecoxib, demonstrated the ability to slow cancer cell growth and limit the presence of known cancer-promoting proteins within the cell samples. Together, EGCG and NS-398 suppressed cell growth by an additional 15 to 28 percent.

The researchers repeated the experiment in mouse models of prostate cancer, using celecoxib and an oral suspension of the decaffeinated green tea polyphenol. By using pharmacy-grade celecoxib and actual tea, they had hoped to replicate real-life conditions. “The idea is that it would be easier to get people to drink green tea than it would be to take an additional dietary supplement,” Mukhtar said.

In mice that were not treated with either substance, the tumor volume averaged 1,300 cubic millimeters, whereas mice given either the tea or celecoxib had tumors averaging 835 cubic millimeters and 650 cubic millimeters, respectively. Tumors taken from mice given both agents, however, measured on average a volume of 350 cubic millimeters.

In parallel to tumor growth inhibition, mice that received a combination of green tea and celecoxib registered a greater decrease in prostate specific antigen (PSA) levels compared to that in celecoxib alone or green tea alone treated animals. PSA is a protein produced by the cells of the prostate and is used as a marker for detection and progression of prostate cancer. These results, combined with a marked decrease in the presence of cancer-promoting proteins, offered clear indications that green tea and celecoxib, combined, could be useful in slowing prostate cancer growth, Mukhtar
'"/>




Page: 1 2 3

Related medicine news :

1. Green tea beneficial in preventing osteoarthritis
2. Eating Greens fights cancer
3. Green Onions Blamed in Outbreak
4. Green Tea Might Help Patients With Prostate Cancer
5. Yet Another Use For Green Tea Extract
6. Exposure To Greenery And Graffiti May Affect Obesity
7. Green Beans for Cancer Prevention and Treatment.
8. Can Green Tea Prevent Alzheimers?
9. Green Tea Consumption Found To Improve Clinical Outcome In Cancer Patients
10. Polyphenols in Green Tea Cause Liver Damage At High Doses
11. FDA Gives Green Signal To Sanofi-Aventis SAs Cancer Drug Taxotere
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Green Tea and COX Inhibitors Combine Slow Growth Prostate Cancer

(Date:10/2/2014)... October 02, 2014 USARAD Holdings ... and telemedicine solutions provider including its SecondOpinions.com® division, ... have joined its Executive Team as President & ... Brent Backhaus, USARAD’s new President and COO, is ... of progressively responsible experience in commercial-, medical- and ...
(Date:10/2/2014)... (PRWEB) October 02, 2014 Robins ... from the Associated Builders and Contractors (ABC) of ... at tonight’s banquet held at Sheraton Birmingham Hotel., ... Massachusetts, Healthcare $10 Million to $25 Million, Obelisk ... Dental Clinic, Federal Government $10 Million to $25 ...
(Date:10/2/2014)... Maureen Salamon HealthDay Reporter ... women with a neurotic personality style and prolonged stress ... new research suggests. Tracking 800 women over nearly ... most anxious, jealous and moody -- which they defined ... the risk of developing Alzheimer,s compared to women scoring ...
(Date:10/2/2014)... HealthDay Reporter WEDNESDAY, Oct. 1, 2014 (HealthDay ... reduced by breast-feeding. Nor will delaying the introduction of a ... help prevent celiac disease. Those are the conclusions ... New England Journal of Medicine . The new ... celiac disease if mothers breast-feed their babies and introduce gluten ...
(Date:10/1/2014)... researchers from the University of Adelaide have developed a ... of a good outcome from treatment - from their ... on a range of factors, including clinical symptoms, cognitive ... in the patient,s blood. , Speaking in the lead ... University,s Head of Psychiatry , Professor Bernhard ...
Breaking Medicine News(10 mins):Health News:Teleradiology and Telemedicine Pioneers Brent Backhaus and Lorna Backhaus Join USARAD Holdings, INC. & SecondOpinions.com® 2Health News:Teleradiology and Telemedicine Pioneers Brent Backhaus and Lorna Backhaus Join USARAD Holdings, INC. & SecondOpinions.com® 3Health News:Robins & Morton wins nine awards from Associated Builders and Contractors 2Health News:Jealous, Moody Women May Face Higher Alzheimer's Risk, Study Says 2Health News:Jealous, Moody Women May Face Higher Alzheimer's Risk, Study Says 3Health News:Infant's Early Diet Doesn't Change Celiac Disease Risk, Study Finds 2Health News:Infant's Early Diet Doesn't Change Celiac Disease Risk, Study Finds 3Health News:Predicting the future course of psychotic illness 2
... , TUESDAY, Jan. 4 (HealthDay News) -- Nearly 60 ... victims of violence, abuse or crime in the past year. ... happened. Researchers led by David Finkelhor of the University ... parents of children up to 9 years old in 2008. More ...
... Reporter , TUESDAY, Jan. 4 (HealthDay News) -- Common ... stem cell defect, a finding that could potentially lead ... study reveals. Researchers say they discovered that a ... stem cells turn into hair-producing progenitor cells. That defect, ...
... , TUESDAY, Jan. 4 (HealthDay News) -- The ... (arrhythmias) that can cause sudden death may be underestimated, ... healthy people without heart disease found detectable changes in ... to polluted air. The findings suggest that air ...
... Jan. 4 (HealthDay News) -- Levels of schooling may affect ... heart attack called acute ST-segment elevation myocardial infarction (STEMI), a ... of heart attack, STEMI occurs when the coronary artery is ... heart. In the new study, Dr. Rajendra H. ...
... Reporter , TUESDAY, Jan. 4 (HealthDay News) -- Simply measuring ... how many years they have left. In fact, a ... older people,s future life span about as well as taking ... disease. Walking speed may not be a perfect window ...
... YORK (Jan. 4, 2011) Researchers have produced a lasting anti-cocaine ... bits of the common cold virus with a particle that mimics ... published Jan. 4 in the online edition of Molecular Therapy ... researchers say this novel strategy might be the first to offer ...
Cached Medicine News:Health News:Survey Finds Much Victimization of Children Goes Unreported 2Health News:Stem Cell Defect Might Help Spur Common Baldness 2Health News:Stem Cell Defect Might Help Spur Common Baldness 3Health News:Higher Education May Benefit Some Heart Attack Patients 2Health News:Fast Walkers May Have More Years Ahead of Them 2Health News:Fast Walkers May Have More Years Ahead of Them 3Health News:Vaccine blocks cocaine high in mice 2Health News:Vaccine blocks cocaine high in mice 3
(Date:10/2/2014)... Oct. 1, 2014 The global high content ... by the ,Threat of Obsolescence, wherein technologies as well ... Pharmaceutical and biotechnology companies as well as academic and ... screening as a powerful research tool in drug discovery. ... segment in the high content screening market. In high ...
(Date:10/1/2014)...  Dyadic International, Inc. ("Dyadic") (OTCQX: DYAI), a ... used to develop and produce enzymes and other ... industrial enzymes industries, today announced the receipt of ... commercial scale production of Abengoa,s proprietary cellulase enzymes, ... Abengoa,s license agreement with Dyadic. ...
(Date:10/1/2014)... 2014 Trovagene, Inc., (NASDAQ:  TROV) a ... Eli Diamond , MD, Assistant Attending Neurologist ... clinical data from an ongoing study demonstrating the ... the determination of oncogene mutational status in cell-free ... were presented to both treating physicians and patients ...
Breaking Medicine Technology:High Content Screening Market by Instruments (Cell Imaging and Analysis System), by Applications (Primary and Secondary Screening, Target Identification and Validation, Toxicity Studies, Compound Profiling), Software & Services - Global Forecasts to 2High Content Screening Market by Instruments (Cell Imaging and Analysis System), by Applications (Primary and Secondary Screening, Target Identification and Validation, Toxicity Studies, Compound Profiling), Software & Services - Global Forecasts to 3Dyadic International Reports Licensing Payment For Commercial-Scale Production Of C1-Based Cellulase Enzymes 2Dyadic International Reports Licensing Payment For Commercial-Scale Production Of C1-Based Cellulase Enzymes 3Clinical Performance of Trovagene's Precision Cancer Monitoring Platform Presented at Second Annual International ECD Medical Symposium 2Clinical Performance of Trovagene's Precision Cancer Monitoring Platform Presented at Second Annual International ECD Medical Symposium 3Clinical Performance of Trovagene's Precision Cancer Monitoring Platform Presented at Second Annual International ECD Medical Symposium 4
... 19, 2011 /PRNewswire-Asia/ -- Winner Medical Group Inc. (Nasdaq: ... leading manufacturer of medical dressings, medical disposables and non-woven ... announced today that the Company will participate in Arab ... 27th, at the International Convention Exhibition Centre in Dubai, ...
... LAKE CITY, Jan. 18, 2011 TechniScan ... device company engaged in the development and commercialization of ... that it has signed a Product Development Agreement with ... $1.5 million. TechniScan and Womens3D will ...
Cached Medicine Technology:Winner Medical to Participate in Arab Health 2011, International Healthcare Exhibition, in Dubai 2Winner Medical to Participate in Arab Health 2011, International Healthcare Exhibition, in Dubai 3TechniScan Signs Agreement With Texas-Based Company to Co-Develop A New Version of Its Breast Imaging Device 2TechniScan Signs Agreement With Texas-Based Company to Co-Develop A New Version of Its Breast Imaging Device 3
... a broad selection of tip ... wide variety of ophthalmic procedures. ... packaged sterile, complete with a ... in the "off " position ...
... Accu-Temp Cauteries provide a broad ... cauterization in a wide variety ... use cautery is packaged sterile, ... to lock switch in the ...
... Cauteries provide a broad selection of ... wide variety of ophthalmic procedures. Each ... complete with a safety cap to ... position when not in use, and ...
... Cauteries provide a broad selection of ... wide variety of ophthalmic procedures. Each ... complete with a safety cap to ... position when not in use, and ...
Medicine Products: