Navigation Links
Grant Encourages Drug Testing Sans Animals

In order to restrict the use animals for the purpose of drug testing which is currently in vogue//, new techniques are being developed by researchers at the University of Manchester, well supported with a whopping 130,000£ as a financial grant.

Gauging the carcinogenic effects of new drugs are often fruitless using current parameters which further necessitates the use of live animals to establish their safety.

Gentronix , a research company founded by Dr Richard Walmsley and colleagues at the University, have developed techniques using cultured human cells to more effectively weed out cancer-causing compounds.

"The current pre-animal tests that are used are highly sensitive and so most carcinogens are identified," said Dr Walmsley, who is based in the Faculty of Life Sciences. "Unfortunately, such tests have poor specificity and a lot of safe compounds are also wrongly identified as potential carcinogens. This means that animal testing is still carried out, in case such compounds turn out to be safe. "The testing process developed at Gentronix has proven very reliable at telling us whether a drug will cause cancer but some chemicals, called promutagens, only become carcinogenic once they have passed through the body's liver.

"This grant will help us develop new non-animal experiments to identify these other toxic compounds and so reduce the need for animal testing."

The funding – awarded by the National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs) – will help the scientists establish new genotoxicity tests using cultured human liver cells. It is hoped the new test will not only reduce the number of compounds that are tested on animals but also ensure harmless chemicals that could prove to be useful new drugs are not falsely labeled as carcinogens.

"I don't believe that animal testing will disappear from drug safety assessment in the short term as you can't ask human volunteers to take novel drugs straight from testing done in tube tests," said Dr Walmsley.

"But if we can refine the pre-animal tests and increase people's confidence in them, then we will be able to reduce the number of chemicals that are tested on live animals."

Source-Eurekalert
MS
'"/>




Related medicine news :

1. Grant of $7 million for Orissa Medical College from Japan
2. Woodruff Foundation Grant To Support Doctorate Of Nursing Practice Program
3. $2.4 Million Grant To Unravel The Mystery Of Language Recognition.
4. Bail Granted To The Doctor Despite Her Patients Death
5. AIDS Funding Grants Dependant on Tracking Patients Names Efficiently
6. NGO Files Pre-Grant Opposition Against Anti-HIV Drug, Combivir
7. Azerbaijan Granted 5 million dollars in Fight Against Bird Flu
8. Rice University wins Prestigious Grants from HHMI
9. Developer Of Vaccine For Cancer Granted A Prestigious Fellowship
10. Indian, Chinese Students In France To Receive Grant From Thales
11. Lenalidomide, Granted Approval by FDA to Join Multiple Myeloma Drugs
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/12/2017)... ... October 12, 2017 , ... The company ... of today’s consumer and regulatory authorities worldwide. From Children’s to Adults 50+, every ... meet the highest standard. , These products are also: Gluten Free, Non-GMO, ...
(Date:10/12/2017)... ... October 12, 2017 , ... The American College of Medical Informatics ... PhD, FACMI, during the Opening Session of AMIA’s Annual Symposium in Washington, D.C. AMIA’s ... of Morris F. Collen, a pioneer in the field of medical informatics, this prestigious ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... that we intend to develop to enable prevention of a major side effect ... hearing loss, especially in pediatric patients. For cisplatin, hearing loss is FDA listed ...
(Date:10/12/2017)... ... October 12, 2017 , ... HMP , a leader in healthcare events ... Magazine Eddie Digital Award for ‘Best B-to-B Healthcare Website.’ Winners were announced during the ... The annual award competition recognizes editorial and design excellence across a range of sectors. ...
(Date:10/12/2017)... ... October 12, 2017 , ... On Saturday, October 21, ... relay – Miles by Moonlight to raise money for the American Heart Association Heart ... , Teams will work together to keep their treadmills moving for 5 hours. ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... INDIANAPOLIS , Oct. 2, 2017  Eli Lilly ... its financial results for the third quarter of 2017 ... a conference call on that day with the investment ... performance. The conference call will begin at ... public can access a live webcast of the conference ...
(Date:10/2/2017)... 2017 The Rebound mobile app is poised to ... the tide of prescription drug addiction. The app empowers users ... and stepping down their dosage in a safe, controlled manner ... 2017; the first 100,000 people to sign up will enjoy ... ...
(Date:9/27/2017)...  Commended for their devotion to personalized service, SMP Pharmacy ... one in the South Florida Business Journal,s 50 Fastest-Growing Companies, ... list, the national specialty pharmacy has found its niche.  To ... soon be honored by SFBJ as the 2017 Power Leader ... to receive his award in October, Bardisa said of the ...
Breaking Medicine Technology: