Navigation Links
Gold Nanoparticles: Agents For Noninvasive Cancer Therapy

Gold nanoparticles are potential and very practical agents in therapeutic applications. Researchers from the University of California, San Francisco and Georgia Institute of Technology, writing Cancer Letters // (Available online 28 September) demonstrate the efficiency of gold nanospheres as photothermal agent by selectively delivering gold nanoparticles to oral carcinoma cells that overexpress EGFR, a clinically related cancer biomarker, and discuss the potential of using this selective technique in molecularly targeted photothermal therapy.

In the study, two oral squamous carcinoma cell lines and one benign epithelial cell line were incubated with anti-epithelial growth factor receptor (EGFR) antibody conjugated gold nanoparticles and then exposed to continuous visible argon ion laser at 514 nm. It was found that the malignant cells required less than half the laser energy to be killed than the benign cells after incubation with anti-EGFR antibody conjugated Gold nanoparticles. No photothermal destruction was observed for all types of cells in the absence of nanoparticles at four times energy required to kill the malignant cells with anti-EGFR/Au conjugates bonded. Gold nanoparticles thus offer a novel class of selective photothermal agents using a CW laser at low powers.

Photodynamic therapy for the management of malignant tumors is gaining acceptance in Europe and United States for various malignancies as new generation of photosensitizers becomes available and technological improvement in the delivery of light occurs. It is an attractive alternative to surgery or radiation with less morbidity and can preserve the anatomic and functional integrity of many organs such as the tongue or larynx.

The study shows that gold nanoparticles could be bound to malignant cells, making cancer detection easier, and the ability of these particles to absorb light helps kill those cancer cells. In conclusion, Gold nanoparticles are a novel class of photothermal agents causing cell injury and death through conversion of the strongly absorbed light to thermal energy. Gold nanoparticles are easily bio-conjugated and are potentially useful with a range of delivery vectors.
'"/>




Related medicine news :

1. New Multi-Modal Contrast Agents, A Boon For Medical Imaging
2. Gamma Knife Offers Noninvasive Treatment for Vascular Disorders, Brain Tumors
3. Hope for Noninvasive Prenatal Test
4. Fibroids unlikely to Turn Cancerous
5. Virus Level could Predict Cervical Cancer Risk
6. Cancer Doctors Okays Controversial Prostate Therapy
7. Potential New Cancer Gene Identified
8. Consensus on "Combination Therapy" for Breast Cancer
9. Cancers of Colon & Rectum linked to Cigarette Smoking
10. Life Saving Cancer Drugs – From Chicken! Possible Says Dolly’ Creatos
11. The Cancer Rumour mill working over time
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/23/2017)... ... June 23, 2017 , ... 21 Middle East and South Asia ... 21 leaders from government, business and civil society in 11 countries across the Middle ... fall, engaging in a transformative exchange of knowledge and ideas with the leading minds ...
(Date:6/23/2017)... ... June 23, 2017 , ... ... Insurance offerings. With the Federal Emergency Management Agency’s (FEMA) recent update of flood ... States. In 2012, the Biggert-Waters Act was enacted to reflect the actual risk ...
(Date:6/23/2017)... ... 2017 , ... The Katyl Agency, a locally owned firm ... owners in and around Lackawanna County, is joining Meals On Wheels of Northeastern ... Meals on Wheels of NEPA provides hand-delivered and nutritious meals to seniors throughout ...
(Date:6/23/2017)... ... June 23, 2017 , ... Radabaugh & Associates, ... families and business owners in North Central West Virginia, is embarking on a ... differently abled residents in the region. , The Stepping Stones organization offers a ...
(Date:6/22/2017)... ... 22, 2017 , ... Plastic Surgery Associates is proud to report that founding ... year, research and information firm, Castle Connolly, releases their list of the most notable ... the 3rd time that Dr. Canales has been recognized by Castle Connolly. ...
Breaking Medicine News(10 mins):
(Date:6/14/2017)... -- ivWatch LLC, a medical device company focused on improving ... pleased to announce it was the Bronze Winner last ... Equipment at the 2017 Medical Design Excellence Awards (MDEAs), ... award was presented by Medical Device and Diagnostics Industry ... New York during MD&M East, the ...
(Date:6/14/2017)... , June 14, 2017  In 2016, Embodied ... Startups pitch competition and came away with $25,000 ... is described by Forbes as "entering the life of ... Association as teaching "empathy to medical professionals in an ... was recently named a finalist for the Department of ...
(Date:6/12/2017)... 12, 2017 Kineta, Inc., a biotechnology company focused ... Vice President of R&D and Head of Virology Kristin ... Preparedness for the Northwest and Beyond meeting sponsored by ... 14, 2017 from 8:30-10:30 AM PDT at the Agora Conference ... Dr. Bedard will be joined by other leaders in ...
Breaking Medicine Technology: