Navigation Links
Gold Nanoparticles: Agents For Noninvasive Cancer Therapy

Gold nanoparticles are potential and very practical agents in therapeutic applications. Researchers from the University of California, San Francisco and Georgia Institute of Technology, writing Cancer Letters // (Available online 28 September) demonstrate the efficiency of gold nanospheres as photothermal agent by selectively delivering gold nanoparticles to oral carcinoma cells that overexpress EGFR, a clinically related cancer biomarker, and discuss the potential of using this selective technique in molecularly targeted photothermal therapy.

In the study, two oral squamous carcinoma cell lines and one benign epithelial cell line were incubated with anti-epithelial growth factor receptor (EGFR) antibody conjugated gold nanoparticles and then exposed to continuous visible argon ion laser at 514 nm. It was found that the malignant cells required less than half the laser energy to be killed than the benign cells after incubation with anti-EGFR antibody conjugated Gold nanoparticles. No photothermal destruction was observed for all types of cells in the absence of nanoparticles at four times energy required to kill the malignant cells with anti-EGFR/Au conjugates bonded. Gold nanoparticles thus offer a novel class of selective photothermal agents using a CW laser at low powers.

Photodynamic therapy for the management of malignant tumors is gaining acceptance in Europe and United States for various malignancies as new generation of photosensitizers becomes available and technological improvement in the delivery of light occurs. It is an attractive alternative to surgery or radiation with less morbidity and can preserve the anatomic and functional integrity of many organs such as the tongue or larynx.

The study shows that gold nanoparticles could be bound to malignant cells, making cancer detection easier, and the ability of these particles to absorb light helps kill those cancer cells. In conclusion, Gold nanoparticles are a novel class of photothermal agents causing cell injury and death through conversion of the strongly absorbed light to thermal energy. Gold nanoparticles are easily bio-conjugated and are potentially useful with a range of delivery vectors.
'"/>




Related medicine news :

1. New Multi-Modal Contrast Agents, A Boon For Medical Imaging
2. Gamma Knife Offers Noninvasive Treatment for Vascular Disorders, Brain Tumors
3. Hope for Noninvasive Prenatal Test
4. Fibroids unlikely to Turn Cancerous
5. Virus Level could Predict Cervical Cancer Risk
6. Cancer Doctors Okays Controversial Prostate Therapy
7. Potential New Cancer Gene Identified
8. Consensus on "Combination Therapy" for Breast Cancer
9. Cancers of Colon & Rectum linked to Cigarette Smoking
10. Life Saving Cancer Drugs – From Chicken! Possible Says Dolly’ Creatos
11. The Cancer Rumour mill working over time
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/18/2017)... ... August 18, 2017 , ... 800response, the leading provider of ... today the launch of a redesigned corporate website, 800response.com . , ... design, and an enhanced search directory for businesses and advertising agencies to use ...
(Date:8/18/2017)... ... August 18, 2017 , ... “Depressed: Super Heroes of the Bible”: ... reflect upon the stories and the relevance these tales may have on the reader’s ... Linhart, a former special education teacher, Jessica spends much of her time enjoying nature ...
(Date:8/18/2017)... ... ... “Case #10-5411 Veterans Administration”: a personal account of corruption ... Administration” is the creation of published author, Carol Mulhern, single mother of two ... work at the Coatesville VAMC as a file clerk then later became the ...
(Date:8/17/2017)... ... August 17, 2017 , ... ... on September 19, 2017 for Anti-Infectives Rx. This off-the-record networking forum of the ... Center at Harvard Medical School. , Industry leaders and decision makers will discuss ...
(Date:8/17/2017)... ... August 17, 2017 , ... Elemental LED, a leading U.S. ... Diode LED products were honored with Architectural SSL Product Innovation Awards ... its manufacturing and wholesale division, Diode LED, provides a wide variety of superior quality ...
Breaking Medicine News(10 mins):
(Date:8/14/2017)... HACKENSACK, N.J. and PETACH TIKVAH, ... Therapeutics Inc. (NASDAQ: BCLI), a leading developer of adult ... for the second quarter ending June 30, 2017. ... advanced stages of preparing for our pivotal Phase 3 ... Chaim Lebovits , President and Chief Executive Officer ...
(Date:8/10/2017)... , Aug. 10, 2017  Physical Rehabilitation Network (PRN), acquired ... Lakewood, Colorado . The reputable clinic will ... , PT, DPT with his staff of four clinicians. Lipkin ... Pittsburgh and brings over 10 years of experience with a ... Belmar PT marks the 10th PRN clinic in and around ...
(Date:8/8/2017)...   Second-quarter 2017 revenues of ... share from continuing operations ... to $110 million Second-quarter ... million Second-quarter 2017 adjusted ... 8 percent to $0.93 ...
Breaking Medicine Technology: