Navigation Links
Glucose may support in Cardiac Arrest

According to a reasonably new research, it was observed that giving most heart attack patients an infusion of glucose soon after they come to the hospital could dramatically improve their chances of survival. The Dutch study found that supplementing regular treatment of heart attacks with the extra fuel reduced the risk of dying //within a month from 4% to 1.5%, but only for patients whose hearts had not suffered substantial damage in the attack.

Researchers suggested that the study's findings were preliminary. Dr. Lars reasonably, a professor of cardiology at the Karolinska Institute in Stockholm, ``The time of follow-up is probably too short to draw firm conclusions,'' who was not involved with the research.

When heart muscle is damaged, the metabolism in the heart increases and the cells need a lot more glucose, their main fuel, to stay alive. The infusion includes insulin, which is needed to transport the glucose into the cell. However, insulin also causes a flux of potassium into cells, which depletes the levels in the blood. Potassium is therefore added to the infusion to compensate for that effect.

In the 1950s and 1960s, several studies investigated the prospect of boosting fuel to the heart with infusions of glucose, insulin and potassium. However, the evidence was inconclusive and doctors were left confused. Also, it has never been tested in combination with today's standard therapies. Those involve trying to get rid of the clot that caused the heart attack either by widening the arteries with instruments or dissolving the clot with drugs.

The latest study involved 900 patients treated at the De Weezenlanden Hospital in Zwolle in the Netherlands. Half the patients also got an infusion of the high-dose glucose mixture. They got about 4.1 pints of the fluid intravenously over 8 hours.

Overall, the death rate over the next 30 days was about the same in the two groups - about 10 percent. However, the res ults significantly improved when restricted to the 90 percent of patients who had not suffered severe damage or heart failure. Only 10 people who got the infusion were dead 30 days later, compared with 18 in the group who didn't get the tonic.

Dr. Felix Zijlstra, a cardiology professor who led the research said that these data show that at least we should take it seriously. ``Metabolic intervention seems to have a future - on top of other therapy and provided they don't have heart failure.''

About three quarters of people who have a heart attack have no signs of heart failure. While experts were encouraged by the glucose findings, they appeared to give up on another infusion for heart patients that had once shown promise - magnesium.

A number of small studies conducted on humans in the 1980s suggested magnesium reduced deaths. But a large study in 1993 failed to find a benefit. However the larger study left open the possibility magnesium could be helpful if given sooner after an attack and to people with a worse prognosis - such as the elderly or people who couldn't have their arteries widened or receive clot-busting drugs. The U.S. National Heart, Lung and Blood Institute funded a Harvard Medical School study of more than 2,000 patients in 12 countries to answer that question.

The findings, presented at the Berlin meeting, showed that magnesium infusions were useless for such patients. Fifteen percent of the patients died in the month after their heart attacks, regardless of whether they had had the magnesium infusion. ``I think magnesium is now dead in the water,'' said Rory Collins, an Oxford University epidemiologist who was not connected with the study.


'"/>




Related medicine news :

1. Treatment For Sleep Apnea Found To Lower Blood Glucose Levels
2. Critically Ill Patients More At Risk Of Infection If Glucose Is Present In Their Lung Secretions
3. Glucose Boosts Memory Retention
4. Glucose Enables Speedy Recovery From Malaria
5. Watch Out For the Erroneous Readings in the Glucose Meters
6. Abnormal Glucose Metabolism May Contribute to Chronic Nerve Disorder
7. Exercise in Itself Improves Blood Glucose Control in Type 2 Diabetes
8. Exercise in Itself Improves Blood Glucose Control in Type 2 Diabetes
9. Study Finds No Benefits On Self Monitoring Blood Glucose levels
10. Two Chemical Compounds Restore Healthy Glucose Levels In Obese Mice
11. Insufficient Sleep Associated with Poorer Blood Glucose Control
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/26/2016)... , ... June 26, 2016 , ... ... once they have been diagnosed with endometriosis. These women need a treatment plan ... require a comprehensive approach that can help for preservation of fertility and ultimately ...
(Date:6/25/2016)... ... 2016 , ... First Choice Emergency Room , the largest network of ... Medical Director of its new Mesquite-Samuell Farm facility. , “We are pleased to ... said Dr. James M. Muzzarelli, Executive Medical Director of First Choice Emergency Room. ...
(Date:6/24/2016)... Los Angeles, CA (PRWEB) , ... June 24, 2016 , ... ... plastic surgery procedures that most people are unfamiliar with. The article goes on to ... known procedures, but also many of these less common operations such as calf and ...
(Date:6/24/2016)... MIAMI, Fla. (PRWEB) , ... June 24, 2016 , ... ... Florida Trend magazine’s 2016 Legal Elite. The attorneys chosen by their peers for this ... of Florida. , Seven Greenberg Traurig Shareholders received special honors as members of this ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... the Clinical Decision Making in Emergency Medicine conference in Ponte Vedra Beach, FL. ... articles published in Emergency Medicine Practice and Pediatric Emergency Medicine Practice. ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 Research and ... Global Market - Forecast to 2022" report to their ... treatment method for the patients with kidney failure, it replaces ... fluid from the patient,s blood and thus the treatment helps ... and chloride in balance. Increasing number of ...
(Date:6/23/2016)... , June 23, 2016 Roche (SIX: ... 510(k) clearance for its Elecsys BRAHMS PCT (procalcitonin) assay ... sepsis or septic shock. With this clearance, Roche is ... a fully integrated solution for sepsis risk assessment and ... with bacterial infection and PCT levels in blood can ...
(Date:6/23/2016)... -- Bracket , a leading clinical trial technology and ... platform, Bracket eCOA (SM) 6.0, at the 52 nd ... 2016 in Philadelphia , Pennsylvania.  A demonstration ... of its kind to fully integrate with RTSM, will be ... is a flexible platform for electronic clinical outcomes assessments that ...
Breaking Medicine Technology: