According to a reasonably new research, it was observed that giving most heart attack patients an infusion of glucose soon after they come to the hospital could dramatically improve their chances of survival. The Dutch study found that supplementing regular treatment of heart attacks with the extra fuel reduced the risk of dying //within a month from 4% to 1.5%, but only for patients whose hearts had not suffered substantial damage in the attack.
Researchers suggested that the study's findings were preliminary. Dr. Lars reasonably, a professor of cardiology at the Karolinska Institute in Stockholm, ``The time of follow-up is probably too short to draw firm conclusions,'' who was not involved with the research.
When heart muscle is damaged, the metabolism in the heart increases and the cells need a lot more glucose, their main fuel, to stay alive. The infusion includes insulin, which is needed to transport the glucose into the cell. However, insulin also causes a flux of potassium into cells, which depletes the levels in the blood. Potassium is therefore added to the infusion to compensate for that effect.
In the 1950s and 1960s, several studies investigated the prospect of boosting fuel to the heart with infusions of glucose, insulin and potassium. However, the evidence was inconclusive and doctors were left confused. Also, it has never been tested in combination with today's standard therapies. Those involve trying to get rid of the clot that caused the heart attack either by widening the arteries with instruments or dissolving the clot with drugs.
The latest study involved 900 patients treated at the De Weezenlanden Hospital in Zwolle in the Netherlands. Half the patients also got an infusion of the high-dose glucose mixture. They got about 4.1 pints of the fluid intravenously over 8 hours.
Overall, the death rate over the next 30 days was about the same in the two groups - about 10 percent. However, the resPage: 1 2 Related medicine news :1
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