Navigation Links
Glucosamine-like Supplement Inhibits Multiple Sclerosis, Type 1 Diabetes

A glucosamine-like dietary supplement has been found to suppress the damaging autoimmune response seen in multiple sclerosis and type 1 diabetes mellitus, according to University of California, Irvine health sciences researchers.

In studies on mice, Dr. Michael Demetriou and colleagues with the UC Irvine Center for Immunology found that N-acetylglucosamine (GlcNAc), which is similar but more effective than the widely available glucosamine, inhibited the growth and function of abnormal T-cells that incorrectly direct the immune system to attack specific tissues in the body, such as brain myelin in MS and insulin-producing cells of the pancreas in diabetes. Study results appear on the online version of the Journal of Biological Chemistry.

This finding shows the potential of using a dietary supplement to help treat autoimmune diseases, said Demetriou, an assistant professor of neurology, and microbiology and molecular genetics. Most importantly, we understand how this sugar-based supplement inhibits the cells that attack the body, making metabolic therapy a rational approach to prevent or treat these debilitating diseases.

The UC Irvine study defines how metabolic therapy with the sugar GlcNAc and other related nutrients modifies the growth and autoimmune activitiy of T-cells. Virtually all proteins on the surface of cells, including T-cells, are modified with complex sugars of variable lengths and composition. Recent studies have shown that changes in these sugars are often associated with T-cell hyperactivity and autoimmune disease.

In mouse models of both MS and type 1 diabetes, Demetriou and colleages found that GlcNAc prevented this hyperactivity and autoimmune response by increasing sugar modifications to the T-cell proteins. This therapy normalized T-cell function and prevented development of paralysis in MS and high blood glucose levels in type 1 diabetes.

This study comes on the heels of
'"/>




Page: 1 2

Related medicine news :

1. B Vitamin Supplementatoin Saves Money and Lives
2. Supplement helps cardiac surgery
3. Mislabeled Body-building Steroid Supplements
4. Garlic Supplements Impede HIV Therapy
5. Lactobacillus Supplements shorten the duration of diarrhoea
6. Supplements for Ear Infections
7. Babies Should Get Vitamin D Supplement
8. Benefits of Vitamin Supplements Unclear
9. Vitamin- B Supplements Beneficial in Depression Treatment
10. Weight Loss Supplements Questioned
11. Vitamin B12 Supplements Found To Improve Memory
Post Your Comments:
(Date:10/1/2014)... Hills, California (PRWEB) October 01, 2014 ... expert, Dr. Kathleen Mojas is celebrating 20 years of ... has assisted hundreds of people to achieve greater joy ... an important list of warning signs and suggestions for ... , Dr. Mojas explains: “Believe it or not, ...
(Date:10/1/2014)... (PRWEB) October 01, 2014 Anti Aging ... and skin rejuvenating destination of choice, is announcing a ... October through to December. , “We’re doing this because ... possible to our top skin clinic in Toronto,” says ... do so much at Anti Aging Clinic, including laser ...
(Date:10/1/2014)... Deland, Florida (PRWEB) October 01, 2014 ... to promote awareness and early detection plans while raising ... to support Breast Cancer Awareness Month in ... Water also wants to promote the importance of having ... contaminated drinking water may be linked to certain forms ...
(Date:10/1/2014)... Generic drug prices are on the ... price in the last 12 months. For its Sept. ... News (DBN) interviewed a plan sponsor and a financial ... health plans. , “When MAC [maximum allowable cost] ... these cost increases squeeze pharmacies’ profits,” explains Adam Fein, ...
(Date:10/1/2014)... After a run of successful premiere ... filmmaker Jacqui Blue is continuing her mission to be ... about natural birth. The documentary has received a tremendous ... and has been an effective medium for starting the ... in the film provide a wealth of information that ...
Breaking Medicine News(10 mins):Health News:Prominent Beverly Hills Psychologist Dr. Kathleen Mojas Celebrating 20 Years in Private Practice Identifies Common Warning Signs That You May Be In a Toxic Relationship. 2Health News:Prominent Beverly Hills Psychologist Dr. Kathleen Mojas Celebrating 20 Years in Private Practice Identifies Common Warning Signs That You May Be In a Toxic Relationship. 3Health News:Anti Aging Clinic, the GTA’s Premier Provider of Anti Aging Treatments, Announces Deal on Units of Botox 2Health News:Pelican Water Supports Breast Cancer Awareness Month with Order Donations 2Health News:Rising Generic Drug Prices Affect Pharmacies, Insurers Alike, Reports AIS Newsletter 2Health News:Rising Generic Drug Prices Affect Pharmacies, Insurers Alike, Reports AIS Newsletter 3Health News:Filmmaker Jacqui Blue's Beautiful Births Documentary, "Really Touched My Heart" 2Health News:Filmmaker Jacqui Blue's Beautiful Births Documentary, "Really Touched My Heart" 3Health News:Filmmaker Jacqui Blue's Beautiful Births Documentary, "Really Touched My Heart" 4
... Western society are suffering from auto-immune diseases. Discovering the ... step in the search for targeted medicines. VIB researchers ... joined forces and have elucidated the function of MALT1, ... are the first to show that MALT1 is able ...
... rumi regulates Notch signaling by adding a glucose molecule ... outside a cell, said researchers from Baylor College of ... York in a report that appears today in the ... protein determines cell fate determination and differentiation. , ...
... Comment, ROLLING MEADOWS, Ill., Jan. 26 ... member specialty,organization of leaders in the field of ... the petition filed by Public Citizen with the,U.S. ... The ASDS supports the current labeling of all ...
... 25 The,American Society of Plastic Surgeons (ASPS) ... products and adverse events following,a recent petition from ... Citizen requested the U.S. Food and Drug,Administration (FDA) ... More than one million people have been ...
... Costs have climbed 32% since 2002, study finds ... and economic costs in the United States hit $174 ... a new study shows. , The research, commissioned by ... for people with diabetes were about $116 billion, and ...
... attempt to end own life, study finds , , FRIDAY, Jan. 25 ... likely to attempt suicide and more than twice as likely to ... study says. , Violent suicide includes hanging, the use of a ... of a vehicle, or drowning. , The increased risk of suicide ...
Cached Medicine News:Health News:A major step toward a more targeted treatment for auto-immune diseases? 2Health News:Notch-ing glucose into place 2Health News:American Society for Dermatologic Surgery Supports Current Labeling of Allergan's Botox(R) Products 2Health News:ASPS Addresses Concerns Regarding BOTOX Treatments 2Health News:Diabetes' Health Toll Hits $174 Billion Annually 2Health News:Short Birth Length Boosts Men's Suicide Risk 2
(Date:9/30/2014)... Sept. 30, 2014 Arbor Pharmaceuticals, LLC. ... Global Markets Direct,s, ,Arbor Pharmaceuticals, LLC. - ... of the Arbor Pharmaceuticals, LLC.,s pharmaceutical research and ... on the current therapeutic developmental pipeline of Arbor ... stages, therapeutics assessment by drug target, mechanism of ...
(Date:9/30/2014)... DENVER , Sept. 30, 2014  According ... "the world of cancer clinical trials is going ... clinical trials and the work of the current ... these types of ,next generation, clinical trials, which ... tomorrow."  The company has been ...
(Date:9/30/2014)... , Sept. 30, 2014 A study ... (OCT), offered a new look at the composition of ... how physicians understand and treat the disease, a leading ... at Baptist Health Lexington between September 2010 and May ... the Journal of the American College of Cardiology ...
Breaking Medicine Technology:Arbor Pharmaceuticals, LLC. - Product Pipeline Review - 2014 2Arbor Pharmaceuticals, LLC. - Product Pipeline Review - 2014 3Small Denver Company Pharmatech driving a large revolution in how cancer clinical trials are managed 2New Imaging Tool May Allow Tailoring of Stroke Prevention to Each Patient 2
... Combination with CRESTOR (rosuvastatin calcium) Demonstrates Similar Lipid Effects ... ... Population, SAN FRANCISCO, June 7 ... type 2 diabetes,that were enrolled in a Phase III study showed ...
... the ADA,s Annual Scientific Sessions, SAN FRANCISCO, ... of the dose-finding study for its new,injectable diabetes ... American Diabetes Association,s (ADA) 68th Annual Scientific Sessions,meeting ... that AVE0010 was well tolerated and significantly,improved glycemic ...
Cached Medicine Technology:Abbott's Phase III Sub-Group Analysis Shows Investigational TriLipix(TM) in Combination with CRESTOR(R) Improves Key Lipids in Patients with Mixed Dyslipidemia and Type 2 Diabetes 2Abbott's Phase III Sub-Group Analysis Shows Investigational TriLipix(TM) in Combination with CRESTOR(R) Improves Key Lipids in Patients with Mixed Dyslipidemia and Type 2 Diabetes 3Abbott's Phase III Sub-Group Analysis Shows Investigational TriLipix(TM) in Combination with CRESTOR(R) Improves Key Lipids in Patients with Mixed Dyslipidemia and Type 2 Diabetes 4New Diabetes Compound AVE0010 Showed Clear Dose Response Results With Once-A-Day Injection in Phase IIb Study 2New Diabetes Compound AVE0010 Showed Clear Dose Response Results With Once-A-Day Injection in Phase IIb Study 3New Diabetes Compound AVE0010 Showed Clear Dose Response Results With Once-A-Day Injection in Phase IIb Study 4
DNA/RNA preparation in 8-multi channels...
... units with hydrophobic PTFE membranes,Millex filter ... ideal for the sterilizing filtration of ... and for sterilizing or clarifying organic ... filter units are available with different ...
... Bottled Water, The Simplicity personal water system ... currently use bottled water. In addition to ... store bottled water, your laboratory applications may ... be absorbed from containers and cause water ...
... of Type I ultrapure water, , Ultrapure ... System is designed to provide the "final ... by reverse osmosis, distillation or deionization. Super-Q ... which exceeds Type I ASTM/CAP/NCCLS specifications.,The Super-Q ...
Medicine Products: