Navigation Links
GlaxoSmithKline's Zofran Helps In Treatment Of Dehydration In Children

The drug Zofran, commonly given in children to limit vomiting can help in the recovery of children dehydrated by viral gastroenteritis //. A latest study released on Wednesday further highlights that emergency room doctors are overusing the drug.

Childhood gastroenteritis accounts for over 1.5 million of the emergency room visits annually. Dehydrated children are being encouraged to drink an electrolyte solution for restoration of fluid electrolyte balance. However vomiting prevents most children from reaping any clinical benefit.

Administration of intravenous fluids is one alternative to enable recovery of children. Another alternative to stop the vomiting is to administer ondansetron, manufactured by GlaxoSmithKline and marketed under the brand name, Zofran, reveals a study published in the New England Journal of Medicine.

The study was conducted on children who had to be hospitalized (Children's Memorial Hospital in Chicago) for their dehydration. The study participants were divided into two groups, one group received Zofran while the other was provided a placebo. Care was taken to ensure that same number of children were included in both the groups. Severely dehydrated children were excluded from the study.

Administration of Zofran was found to reduce the need for intravenous intervention or IV therapy. As little as 14% of the 107 children treated with Zofran needed intravenous fluid administration for treatment of dehydration, while 31% of those who received a placebo needed fluid replacement in the form of IV therapy.

'Children who received ondansetron had fewer episodes of vomiting, greater oral intake of fluids and a shorter stay in the emergency department. We were seeing physicians in private hospital emergency departments that were doing this for everybody,' said Stephen Freedman who led the research team.

The distinct advantage of administering Zofran is that it is more cost-effectiv e than an IV treatment and prevents pain associated with needle picks, which is very valuable in children. For example, IV treatment of a child costs $125 at Children's Memorial Hospital, where the study was done. On the other hand, Zofran tablet, which is a quick dissolve formulation, costs $36 per tablet, substantially reducing the treatment cost.


'"/>




Related medicine news :

1. Antibiotics Helps Autism
2. Serum Progesterone Helps Stratify Ectopic Pregnancy Risk
3. Prescription Drug - Helps People Stop Smoking
4. New Drug PP188 Helps Sickle Cell Disease
5. Red Wine Helps Fight Heart disease
6. Creatine Helps Strengthen Older Men
7. Cholesterol Drug Helps After Angioplasty
8. Virus Helps Remove Brain Cancer
9. Eating Fish Helps the Heart
10. Antidepressant Helps Relieve Hot Flashes
11. Epilepsy Drug Helps Diabetic Nerve Damage
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/26/2016)... ... ... There are many ways to cook a hot dog, but new research commissioned ... dogs straight off the grill. Of the 90 percent of Americans who say they ... hot dog, far outpacing other cooking methods such as steaming (12 percent), microwaving (9 ...
(Date:5/26/2016)... ... May 26, 2016 , ... Connor Sports, through its ... partner for the Tamika Catchings Legacy Tour that will commemorate the Indiana ... hardwood basketball surfaces in all forms and levels of the game, Connor Sports has ...
(Date:5/26/2016)... ... May 26, 2016 , ... MadgeTech will be showcasing its line ... in Warner, New Hampshire at the MadgeTech headquarters. With products sold in more than ... by government agencies, including NASA. , In 2012, NASA strategically set up 17 ...
(Date:5/26/2016)... ... May 26, 2016 , ... Memorial Day Weekend marks ... Amica Insurance is sharing tips to make sure your family and vehicle are ... National Safety Council, there may be 439 deaths and an additional 50,500 serious injuries ...
(Date:5/26/2016)... ... May 26, 2016 , ... ... a multitude of activities from daily practices, arts & crafts, discussions, and games ... Amber East-D’Anna and Christy Evans have combined backgrounds in kids’ yoga, collegiate sport ...
Breaking Medicine News(10 mins):
(Date:5/24/2016)... May 24, 2016 Celsion Corporation (NASDAQ: ... company, today provided an update on its ongoing ... trial combining GEN-1, the Company,s DNA-based immunotherapy, with ... newly-diagnosed patients with advanced ovarian cancer who will ... GEN-1 is an IL-12 DNA plasmid vector formulated ...
(Date:5/24/2016)... HONG KONG , May 24, 2016 /PRNewswire/ ... primer stent de doble terapia del mundo, introduce ... fístula arteriovenosa. OrbusNeich, una compañía global ... cambian las vidas, ha expandido su cartera incluyendo ... catéteres balón JADE™ y Scoreflex™ PTA son los ...
(Date:5/24/2016)... Dutch surgeons have launched a ground-breaking medical app to help doctors ... a global scale. Medical professionals from Europe , ... the US have already signed up for the app, which combines ... environment. Education  "Imagine a doctor for Medicines ... at Harvard to treat a bomb victim via live streaming - ...
Breaking Medicine Technology: