The drug Zofran, commonly given in children to limit vomiting can help in the recovery of children dehydrated by viral gastroenteritis //. A latest study released on Wednesday further highlights that emergency room doctors are overusing the drug.
Childhood gastroenteritis accounts for over 1.5 million of the emergency room visits annually. Dehydrated children are being encouraged to drink an electrolyte solution for restoration of fluid electrolyte balance. However vomiting prevents most children from reaping any clinical benefit.
Administration of intravenous fluids is one alternative to enable recovery of children. Another alternative to stop the vomiting is to administer ondansetron, manufactured by GlaxoSmithKline and marketed under the brand name, Zofran, reveals a study published in the New England Journal of Medicine.
The study was conducted on children who had to be hospitalized (Children's Memorial Hospital in Chicago) for their dehydration. The study participants were divided into two groups, one group received Zofran while the other was provided a placebo. Care was taken to ensure that same number of children were included in both the groups. Severely dehydrated children were excluded from the study.
Administration of Zofran was found to reduce the need for intravenous intervention or IV therapy. As little as 14% of the 107 children treated with Zofran needed intravenous fluid administration for treatment of dehydration, while 31% of those who received a placebo needed fluid replacement in the form of IV therapy.
'Children who received ondansetron had fewer episodes of vomiting, greater oral intake of fluids and a shorter stay in the emergency department. We were seeing physicians in private hospital emergency departments that were doing this for everybody,' said Stephen Freedman who led the research team.
The distinct advantage of administering Zofran is that it is more cost-effectivPage: 1 2 Related medicine news :1
. Antibiotics Helps Autism2
. Serum Progesterone Helps Stratify Ectopic Pregnancy Risk
. Prescription Drug - Helps People Stop Smoking4
. New Drug PP188 Helps Sickle Cell Disease 5
. Red Wine Helps Fight Heart disease 6
. Creatine Helps Strengthen Older Men7
. Cholesterol Drug Helps After Angioplasty8
. Virus Helps Remove Brain Cancer9
. Eating Fish Helps the Heart10
. Antidepressant Helps Relieve Hot Flashes11
. Epilepsy Drug Helps Diabetic Nerve Damage