Navigation Links
Genome of Botulism Bacterium Revealed

The Botulism bacterium, Clostridium botulinum, produces the world's most lethal toxin. Less than 2 kg is enough to wipe off humanity from the face of the earth! Botox , that contains miniscule amounts of the toxin, is used medically.

Now, the genome of the organism is exposed. The report in Genome Research reveals that the bacterium does not possess the means to escape human defences or resist antibiotics. C. botulinum exists as a dormant spore or a scavenger of decaying animal remains in the soil; its interaction with human or other large animal hosts does not involve long periods of time.

Occasionally it gets into a living animal, via contaminated food or open wounds, leading to infant botulism or wound botulism, both of which are serious human infections. The host can be quickly overpowered and, in some cases, killed by the toxin, and C. botulinum has a new food source.

"Although in the same group as Clostridium difficile - the Cdiff superbug - C. botulinum has a genome that is remarkable because it is so stable, "commented Dr Mohammed Sebaihia, lead author on the paper from the Wellcome Trust Sanger Institute. "Unlike Cdiff, in which more than 10% of genes have been acquired from other bacteria, there is almost no footprint of these in C. botulinum."

There are several types of C. botulinum: although described as variants of a single species, they are really very different organisms linked simply because they have the deadly toxin. For each type, there is also a near-identical but harmless relative that lacks the toxin. C. sporogenes is the non-malignant, near twin of the organism sequenced.

Professor Mike Peck, from the Institute of Food Research, commented that "It is astonishing that 43% of the predicted genes in the C. botulinum genome are absent from the other five sequenced clostridia, and only 16% of the C. botulinum genes are common to all five. Our findings emphasise just how different
'"/>




Page: 1 2 3

Related medicine news :

1. Human Genome Project Achieves Technological Triumph
2. Human Diseases May Have Clue In Human-Chimp Genome Difference
3. Race Based Genome Project Launched By Mexico
4. Dog (Mans best friend) Genome Sequenced
5. Decoding the Fungi Genome Will Save Millions of Lives.
6. Yeast Genome Unravels Genes Critical For Maintaining DNA Integrity
7. Unraveling the Secrets of MHC in Human Genome
8. NHGRI Aims To Sequence Primate Genomes
9. p53, the Guardian of Our Genome
10. Genome Code Cracked for Breast and Colon Cancers
11. Sea Urchin Genome Similar To Man And May Cure Diseases
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Genome Botulism Bacterium Revealed

(Date:4/19/2015)... Indiana (PRWEB) April 19, 2015 ... statewide Network Service Provider, announces a major bandwidth ... (AdamsWells) in Bluffton, IN. Craigville Telephone Company, ... has expanded service on IFN’s protected 10 Gigabit ... Zehner, IFN’s Vice President of Sales and Marketing, ...
(Date:4/18/2015)... CA (PRWEB) April 19, 2015 For some ... will proudly display for the rest of their lives, as ... obtaining them and put in a great amount of thought ... a whim, they have outgrown them or simply want them ... of people regret their tattoo, and in 2012-13 there was ...
(Date:4/18/2015)... Carinsurancequotesinfo.com has released a new blog post ... caused by a car accident. , Car ... vehicle. A policy can pay for car repairs and ... always carry appropriate coverage when they are driving. ... with several important riders that offer extra coverage options. ...
(Date:4/18/2015)... 18, 2015 "I recognized the need ... healthcare facilities," said an inventor from Cincinnati, Ohio. "This ... , He developed the Slyde Door to offer an ... healthcare facilities. It provides convenient storage space for an ... stretchers available for patients. , This offers added ...
(Date:4/18/2015)... Insuranceautoquote.info has released a new blog post explaining how ... , Clients can review important auto insurance quotes online, ... important advantages for clients who need affordable financial security ... have coverage for their vehicles can purchase a policy ... Many agencies offer important discounts and drivers can learn ...
Breaking Medicine News(10 mins):Health News:AdamsWells Internet Telecom TV Expands Bandwidth via Indiana Fiber Network, LLC 2Health News:Dennis Dass, M.D. is Shattering the Past While Revealing the Future 2Health News:Auto Insurance Plans Can Cover Physical Injuries Caused By An Accident! 2Health News:Clients Can Review Car Insurance Quotes Online To Find Low Cost Offers! 2
... to reduce transmission from mother to child, experts say ... HIV infection in infants are significantly higher among blacks ... to reduce the disparity, a new government report says. ... overall, among black babies, the rate of perinatal HIV ...
... , SACRAMENTO, Calif. , Feb. 4 ... CEO and Meg Heim, RN , Vice President of Marketing ... Force Committee on behalf of the Governor of California , ... California Department of Chronic Disease and Injury Prevention (CDPH).  The committee ...
... , ATLANTA , Feb. 4 ... Financial Management Association (HFMA) performed a rigorous assessment of ... by Surgical Information Systems, and determined that it meets ... the areas of effectiveness, quality and usability, price, value, ...
... , HAMILTON, Bermuda , ... ("XL" or the "Company") today announced that Chief Executive,Officer Michael S. ... 2010 at the Mandarin Oriental Hotel in Miami, Florida ,on ... A live webcast of Mr. McGavick,s presentation will ...
... , , EDF Testifies 20 Million+ Residents in South ... Calif. , Feb. 4 Environmental Defense Fund ... Standard (NAAQS) for ozone pollution from 75 to 60 parts ... reduce asthma cases 50-fold, according to analyses by the Environmental Protection ...
... (Feb. 4, 2010) Patients with mild gallstone pancreatitis usually ... symptoms to subside, before undergoing surgery to remedy the condition. ... Institute (LA BioMed) indicates patients may no longer have to ... sooner. The study, slated for publication in the ...
Cached Medicine News:Health News:Black and Hispanic Infants Much More Likely to Have HIV 2Health News:BioMedix Vascular Solutions, Inc. Invited to Participate in the California P.A.D. Task Force Committee 2Health News:SIS Rules-Based Charging Solution Successfully Peer Reviewed by HFMA for Third Consecutive Year 2Health News:SIS Rules-Based Charging Solution Successfully Peer Reviewed by HFMA for Third Consecutive Year 3Health News:XL Capital Ltd to Present at Credit Suisse Financial Services Forum on February 11, 2010 2Health News:Stronger Ozone Standard Could Dramatically Reduce Asthma, Premature Deaths 2Health News:Stronger Ozone Standard Could Dramatically Reduce Asthma, Premature Deaths 3Health News:Patients with mild gallstone pancreatitis can undergo surgery sooner, shortening hospital stays 2
(Date:4/17/2015)... April 17, 2015  Trovagene, Inc., (NASDAQ:  TROV) ... that clinical data presented at the 2015 European ... Precision Cancer Monitoring ℠ (PCM) platform outperformed ... EGFR T790M mutations in metastatic lung ... EGFR T790M Mutation in Urinary Circulating Tumor DNA ...
(Date:4/17/2015)... 17, 2015 Steven Rash , the CEO ... its operating subsidiary American Seed & Oil Company, presented ... investors yesterday in New York City.  Mr. Rash,s presentation ... American Seed & Oil Company has recently announced the ... Hemp Seed Foods , the EpiVape , and ...
(Date:4/17/2015)... , Apr. 16, 2015 Research and Markets ... of the "Corporate Reputation of Pharma in 2014 ... 1st Edition" report to their offering. ... compared opinions on the corporate reputation of the pharmaceutical ... mental health with the views of patient organisations representing ...
Breaking Medicine Technology:Trovagene's Urinary ctDNA Assay Outperforms Tissue Biopsy in Clinical Study for the Detection of EGFR T790M Mutations in Metastatic Lung Cancer Patients 2Trovagene's Urinary ctDNA Assay Outperforms Tissue Biopsy in Clinical Study for the Detection of EGFR T790M Mutations in Metastatic Lung Cancer Patients 3Trovagene's Urinary ctDNA Assay Outperforms Tissue Biopsy in Clinical Study for the Detection of EGFR T790M Mutations in Metastatic Lung Cancer Patients 4American Seed & Oil Company Benchmarks its Consumer Product Development Strategy Against Proctor & Gamble 2American Seed & Oil Company Benchmarks its Consumer Product Development Strategy Against Proctor & Gamble 3Corporate Reputation of Pharma in 2014 - The Perspective of Mental Health Patient Groups - 1st Edition 2Corporate Reputation of Pharma in 2014 - The Perspective of Mental Health Patient Groups - 1st Edition 3
... 23, 2011 Dr. Michael Hayden, a Xenon founder ... Wightman Award for leadership in medical science in Canada. ... for Dr. Hayden, having previously been awarded the Order ... Institutes of Health Research,s Health Researcher of the Year ...
... 22, 2011 Boston Scientific Corporation (NYSE: BSX ... on April 4, 2011 at the 60th Annual Scientific Session ... The Company will provide an update on its Cardiology, Rhythm ... heart technologies.  The event is scheduled to begin at 6 ...
Cached Medicine Technology:Xenon Chief Scientific Officer, Dr. Michael Hayden Receives Prestigious Award for Leadership in Medicine 2
Superior imaging through a 410,000 pixel CCD, unseen color replication from a digital signal processor in the scope, and the added benefit of four way tip deflection make the TF410 a superior choice ...
The ACMI™ Operative Laparoscopy System is designed for single- and dual-incision CO2 laser procedures and is used with 45cm laparoscopic instruments....
Stryker autoclavable pediatric laparoscopes provide equivalent brightness and resolution along with the unparalleled durability found in larger laparoscopes....
The Olympus full range of laparoscopes includes a range of diameters and directions of view -12 mm HDTV compatible model as well as a choice of 10 mm, 5 mm full screen and 3 mm....
Medicine Products: