Navigation Links
Genetically modified bacteria to combat HIV

In a breakthrough, which could eventually lead to a practical and cost effective new way to combat the HIV virus, scientists from the US National Cancer Institute have genetically modified bacteria living in the human body to produce chemicals that block HIV infection. //

Most HIV transmission occurs on the surfaces of the gut and reproductive areas, which are normally coated with a layer of bacteria.

The researchers have successfully modified one of these bacteria - a form of E. coli - so that it began to secrete proteins that block HIV from infecting its target cells. When the modified bacteria were introduced in mice, they successfully colonized parts of the lower gut, and were also found in lower concentrations in the vagina.

The research findings appear in the journal Proceedings of the National Academy of Sciences.

Writing in the journal, the researchers said there was an urgent need for new ways to prevent the spread of HIV, especially in the developing world.

The researchers believe their approach has the potential to offer more lasting protection. Also, bacteria are simple and practical to manufacture, store, distribute and administer, and they are far less expensive than protein-based microbicides.

They also believe the method could be adapted to deliver bacteria secreting different proteins to different parts of the body.

Although primarily designed to prevent new HIV infections, they believe it could also be used, in combination with drug therapy, to treat people already carrying the virus.

Commenting on the new research, Dr Tim Farley, of the World Health Organization, said: "In principle a technique such as this which enhances the body's defenses against HIV sounds like a great idea.

"Clearly there are many steps to be completed in the development and clinical testing of the product, and there may be special safety concerns over unexpe cted side effects due to deliberately colonizing the gastrointestinal tract with genetically engineered bacteria."

Although the research tested on mice is still in early stage, the researchers hope it could eventually lead to a practical and cost effective new way to combat the virus.


'"/>




Related medicine news :

1. Malaria To Be Tackled By Genetically Modified Mosquitoes
2. Genetically modified rice faces strong protests in Asia
3. Asthma And Obesity Are Genetically Linked
4. Women Are Genetically More Prone To Depression
5. Genetically modified Lactic acid bacteria offers HIV protection
6. Regulators Object Drug Produced from Genetically Engineered Farm Animals
7. Cocaine Acts As Suppressant Not Stimulant In Genetically Altered Mice
8. Multiple Sclerosis in Genetically Susceptible Twins is Augmented by Northern Environment
9. Humans Genetically More Suited To Being Vegetarians Than Meat-eaters
10. Indian American have Genetically Engineered Edible Cottonseed
11. USDA Gives Go-Ahead to Market Controversial Genetically Engineered Rice, LL601
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... Many families have long-term insurance that covers care ... have a waiver for care if the client has a cognitive impairment diagnosis. ... for care, is often waived, so the benefits from their insurance start immediately,” said ...
(Date:10/13/2017)... ... ... Global Healthcare Management’s 4th Annual Kids Fun Run brought out many kids this ... by Global Healthcare Management’s CEO, Jon Letko, is aimed at getting kids excited about ... ages; it is a non-competitive, non-timed event, which is all about having fun and ...
(Date:10/13/2017)... , ... October 13, 2017 , ... ... and Agile Software Development, has been awarded a contract by the Center for ... Agreement (BPA) aims to accelerate the enterprise use of Agile methodologies in a ...
(Date:10/12/2017)... WILMINGTON, Del. (PRWEB) , ... October 12, 2017 ... ... technology and advisory services for healthcare compliance program management, will showcase a range ... and National Association for Assisted Living (NCAL) Convention and Expo to be held ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... to meet the demand of today’s consumer and regulatory authorities worldwide. From Children’s ... experts and tested to meet the highest standard. , These products are ...
Breaking Medicine News(10 mins):
(Date:9/23/2017)... , Sept. 22, 2017 Janssen Biotech, ... complete response letter from the U.S. Food and Drug ... approval of sirukumab for the treatment of moderately to ... indicates additional clinical data are needed to further evaluate ... to severely active RA. ...
(Date:9/19/2017)... , Sept. 19, 2017   ZirMed Inc ., a ... today announced that it has been ranked #1 by its ... Book™ Rankings 2017 User Survey. ZirMed was recognized as ... large hospitals and medical centers over 200 beds and holds ... healthcare technology user survey history. ...
(Date:9/12/2017)... , Sept. 12, 2017   EcoVadis , the leading platform for ... the first annual edition of its Global CSR Risk and Performance Index. ... by EcoVadis, based on Scorecard Ratings that analyzed nearly 800,000 data points ... ... ...
Breaking Medicine Technology: