Navigation Links
Genetically modified bacteria to combat HIV

In a breakthrough, which could eventually lead to a practical and cost effective new way to combat the HIV virus, scientists from the US National Cancer Institute have genetically modified bacteria living in the human body to produce chemicals that block HIV infection. //

Most HIV transmission occurs on the surfaces of the gut and reproductive areas, which are normally coated with a layer of bacteria.

The researchers have successfully modified one of these bacteria - a form of E. coli - so that it began to secrete proteins that block HIV from infecting its target cells. When the modified bacteria were introduced in mice, they successfully colonized parts of the lower gut, and were also found in lower concentrations in the vagina.

The research findings appear in the journal Proceedings of the National Academy of Sciences.

Writing in the journal, the researchers said there was an urgent need for new ways to prevent the spread of HIV, especially in the developing world.

The researchers believe their approach has the potential to offer more lasting protection. Also, bacteria are simple and practical to manufacture, store, distribute and administer, and they are far less expensive than protein-based microbicides.

They also believe the method could be adapted to deliver bacteria secreting different proteins to different parts of the body.

Although primarily designed to prevent new HIV infections, they believe it could also be used, in combination with drug therapy, to treat people already carrying the virus.

Commenting on the new research, Dr Tim Farley, of the World Health Organization, said: "In principle a technique such as this which enhances the body's defenses against HIV sounds like a great idea.

"Clearly there are many steps to be completed in the development and clinical testing of the product, and there may be special safety concerns over unexpe cted side effects due to deliberately colonizing the gastrointestinal tract with genetically engineered bacteria."

Although the research tested on mice is still in early stage, the researchers hope it could eventually lead to a practical and cost effective new way to combat the virus.


'"/>




Related medicine news :

1. Malaria To Be Tackled By Genetically Modified Mosquitoes
2. Genetically modified rice faces strong protests in Asia
3. Asthma And Obesity Are Genetically Linked
4. Women Are Genetically More Prone To Depression
5. Genetically modified Lactic acid bacteria offers HIV protection
6. Regulators Object Drug Produced from Genetically Engineered Farm Animals
7. Cocaine Acts As Suppressant Not Stimulant In Genetically Altered Mice
8. Multiple Sclerosis in Genetically Susceptible Twins is Augmented by Northern Environment
9. Humans Genetically More Suited To Being Vegetarians Than Meat-eaters
10. Indian American have Genetically Engineered Edible Cottonseed
11. USDA Gives Go-Ahead to Market Controversial Genetically Engineered Rice, LL601
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/12/2016)... ... February 12, 2016 , ... ... exclusively to funding innovative lymphoma research and serving the lymphoma community through a ... 250 members of South Florida’s philanthropic community at its 10th anniversary Fashion Luncheon ...
(Date:2/12/2016)... Middletown, PA (PRWEB) , ... February 12, 2016 , ... ... year’s event will be held in Anaheim, CA at the Anaheim Convention Center. Almost ... they can see new therapy products in action, learn more about their chosen field ...
(Date:2/12/2016)... ... February 12, 2016 , ... T.E.N., a technology and ... the ISE Southeast Awards 2016. Finalists and winners of the ISE® Awards for ... Forum and Awards Gala on March 15, 2016 at the Westin Peachtree Plaza, ...
(Date:2/12/2016)... ... 2016 , ... Every winter, someone is killed, injured or loses a home ... Center, part of the Allegheny Health Network, has partnered with Etna Volunteer Fire ... Need Space” campaign. , “Space Heaters Need Space” aims to bring awareness ...
(Date:2/12/2016)... ... February 12, 2016 , ... The Jones Agency, a family owned insurance ... is launching a cooperative charity drive with the Tarrant Area Food Bank in the ... individuals and families in need, the Tarrant County Food Bank offers hope and security ...
Breaking Medicine News(10 mins):
(Date:2/12/2016)... Affairs leaders at pharmaceutical organizations are looking to either start or ... some companies have conducted a significant number of clinical trials in ... as India and China ... India are now requiring local clinical trials to win ... China and India are ...
(Date:2/12/2016)... , Feb. 12, 2016  Innophos Holdings, Inc. (NASDAQ: ... specialty ingredients, today announced that it will host a live ... ET to discuss its fourth quarter and full year 2015 ... The press release detailing fourth quarter and full year results ... close. --> --> ...
(Date:2/12/2016)... VIEJO , Kalifornien, 12. Februar 2016 /PRNewswire/ ... mit der Aufnahme von Patienten für eine Studie ... von Aneurysmen („WEB") speziell für die Behandlung von ... Spelle , MD, Leiter der Neuroradiologie an der ... Frankreich, und Hauptprüfarzt der CLARYS-Studie hat den ersten ...
Breaking Medicine Technology: