Navigation Links
Genetically modified bacteria to combat HIV

In a breakthrough, which could eventually lead to a practical and cost effective new way to combat the HIV virus, scientists from the US National Cancer Institute have genetically modified bacteria living in the human body to produce chemicals that block HIV infection. //

Most HIV transmission occurs on the surfaces of the gut and reproductive areas, which are normally coated with a layer of bacteria.

The researchers have successfully modified one of these bacteria - a form of E. coli - so that it began to secrete proteins that block HIV from infecting its target cells. When the modified bacteria were introduced in mice, they successfully colonized parts of the lower gut, and were also found in lower concentrations in the vagina.

The research findings appear in the journal Proceedings of the National Academy of Sciences.

Writing in the journal, the researchers said there was an urgent need for new ways to prevent the spread of HIV, especially in the developing world.

The researchers believe their approach has the potential to offer more lasting protection. Also, bacteria are simple and practical to manufacture, store, distribute and administer, and they are far less expensive than protein-based microbicides.

They also believe the method could be adapted to deliver bacteria secreting different proteins to different parts of the body.

Although primarily designed to prevent new HIV infections, they believe it could also be used, in combination with drug therapy, to treat people already carrying the virus.

Commenting on the new research, Dr Tim Farley, of the World Health Organization, said: "In principle a technique such as this which enhances the body's defenses against HIV sounds like a great idea.

"Clearly there are many steps to be completed in the development and clinical testing of the product, and there may be special safety concerns over unexpe cted side effects due to deliberately colonizing the gastrointestinal tract with genetically engineered bacteria."

Although the research tested on mice is still in early stage, the researchers hope it could eventually lead to a practical and cost effective new way to combat the virus.


'"/>




Related medicine news :

1. Malaria To Be Tackled By Genetically Modified Mosquitoes
2. Genetically modified rice faces strong protests in Asia
3. Asthma And Obesity Are Genetically Linked
4. Women Are Genetically More Prone To Depression
5. Genetically modified Lactic acid bacteria offers HIV protection
6. Regulators Object Drug Produced from Genetically Engineered Farm Animals
7. Cocaine Acts As Suppressant Not Stimulant In Genetically Altered Mice
8. Multiple Sclerosis in Genetically Susceptible Twins is Augmented by Northern Environment
9. Humans Genetically More Suited To Being Vegetarians Than Meat-eaters
10. Indian American have Genetically Engineered Edible Cottonseed
11. USDA Gives Go-Ahead to Market Controversial Genetically Engineered Rice, LL601
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/27/2016)... , ... May 27, 2016 , ... More than a ... it is not surprising that bariatric surgery has received increased attention in recent years, ... Of course, when it comes to weight loss, most people are familiar with the ...
(Date:5/27/2016)... ... 2016 , ... With over 60 percent of acute stroke survivors being left ... to aid in the rehabilitation process has steadily increased. Ekso Bionics had been working ... due to stroke. , Ekso Bionics has now received clearance from the U.S. Food ...
(Date:5/27/2016)... , ... May 27, 2016 , ... ... installment is bolstered by inspiring human interest stories, courtesy of leaders in the ... and tech within the industry, from leading advocates and associations—namely Jones & Bartlett ...
(Date:5/26/2016)... ... May 26, 2016 , ... There are many ways to cook a ... (NHDSC) suggests that Americans prefer their dogs straight off the grill. Of the 90 ... their favorite way to cook a hot dog, far outpacing other cooking methods such ...
(Date:5/26/2016)... ... 26, 2016 , ... Connor Sports, through its Connor Cares initiative, ... Tamika Catchings Legacy Tour that will commemorate the Indiana Fever legend’s hall-of-fame ... in all forms and levels of the game, Connor Sports has committed to a ...
Breaking Medicine News(10 mins):
(Date:5/24/2016)... 2016 The innovator of ... , s first dual therapy stent, introduces catheters ... OrbusNeich, a global company specializing in the provision ... include products to treat peripheral artery disease. The JADE™ ... devices for lower limb and arteriovenous (AV) fistula intervention. ...
(Date:5/24/2016)... , May 24, 2016 ... ™ , la première endoprothèse à ... destinés à l,intervention portant sur les membres ... OrbusNeich, entreprise mondiale spécialisée dans ... changer la vie, a élargi son portefeuille ...
(Date:5/24/2016)... Dutch surgeons have launched a ground-breaking medical app to help doctors ... a global scale. Medical professionals from Europe , ... the US have already signed up for the app, which combines ... environment. Education  "Imagine a doctor for Medicines ... at Harvard to treat a bomb victim via live streaming - ...
Breaking Medicine Technology: