Navigation Links
Genetically modified bacteria to combat HIV

In a breakthrough, which could eventually lead to a practical and cost effective new way to combat the HIV virus, scientists from the US National Cancer Institute have genetically modified bacteria living in the human body to produce chemicals that block HIV infection. //

Most HIV transmission occurs on the surfaces of the gut and reproductive areas, which are normally coated with a layer of bacteria.

The researchers have successfully modified one of these bacteria - a form of E. coli - so that it began to secrete proteins that block HIV from infecting its target cells. When the modified bacteria were introduced in mice, they successfully colonized parts of the lower gut, and were also found in lower concentrations in the vagina.

The research findings appear in the journal Proceedings of the National Academy of Sciences.

Writing in the journal, the researchers said there was an urgent need for new ways to prevent the spread of HIV, especially in the developing world.

The researchers believe their approach has the potential to offer more lasting protection. Also, bacteria are simple and practical to manufacture, store, distribute and administer, and they are far less expensive than protein-based microbicides.

They also believe the method could be adapted to deliver bacteria secreting different proteins to different parts of the body.

Although primarily designed to prevent new HIV infections, they believe it could also be used, in combination with drug therapy, to treat people already carrying the virus.

Commenting on the new research, Dr Tim Farley, of the World Health Organization, said: "In principle a technique such as this which enhances the body's defenses against HIV sounds like a great idea.

"Clearly there are many steps to be completed in the development and clinical testing of the product, and there may be special safety concerns over unexpe cted side effects due to deliberately colonizing the gastrointestinal tract with genetically engineered bacteria."

Although the research tested on mice is still in early stage, the researchers hope it could eventually lead to a practical and cost effective new way to combat the virus.


'"/>




Related medicine news :

1. Malaria To Be Tackled By Genetically Modified Mosquitoes
2. Genetically modified rice faces strong protests in Asia
3. Asthma And Obesity Are Genetically Linked
4. Women Are Genetically More Prone To Depression
5. Genetically modified Lactic acid bacteria offers HIV protection
6. Regulators Object Drug Produced from Genetically Engineered Farm Animals
7. Cocaine Acts As Suppressant Not Stimulant In Genetically Altered Mice
8. Multiple Sclerosis in Genetically Susceptible Twins is Augmented by Northern Environment
9. Humans Genetically More Suited To Being Vegetarians Than Meat-eaters
10. Indian American have Genetically Engineered Edible Cottonseed
11. USDA Gives Go-Ahead to Market Controversial Genetically Engineered Rice, LL601
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/12/2017)... Rockville, Maryland (PRWEB) , ... October 12, 2017 ... ... a magnetic drug delivery system that we intend to develop to enable prevention ... regimens can lead to severe hearing loss, especially in pediatric patients. For cisplatin, ...
(Date:10/12/2017)... PA (PRWEB) , ... October 12, 2017 , ... ... is the recipient of a 2017 Folio Magazine Eddie Digital Award for ‘Best B-to-B ... York City on October 11, 2017. , The annual award competition recognizes editorial and ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... On Saturday, ... a treadmill relay – Miles by Moonlight to raise money for the American Heart ... or more. , Teams will work together to keep their treadmills moving for ...
(Date:10/12/2017)... ... October 12, 2017 , ... Health Literacy Innovations (HLI), creator ... tool, and the Cancer Patient Education Network (CPEN), an independent professional organization that ... new strategic alliance. , As CPEN’s strategic partner, HLI will help support ...
(Date:10/12/2017)... FL (PRWEB) , ... October 12, 2017 , ... ... presenting the latest in wound care advancements to physician colleagues, skilled nursing facility ... is titled, "Navigating the Treacherous Waters of Wound Care." , "At many of ...
Breaking Medicine News(10 mins):
(Date:9/22/2017)... Sept. 22, 2017 AVACEN Medical (AVACEN) announced ... now successfully helping those with the widespread pain associated ... diagnosed Amanda in Essex, England ... my hair, experiencing no sleep at all, tremendous pain, ... I cannot recommend [the AVACEN 100] enough, how this ...
(Date:9/18/2017)... , Pa. and KALAMAZOO, Mich. , ... Allentown, Penn. , and OptiMed Specialty Pharmacy of ... business partnership to offer a strategic hub service that ... Healthcare,s highly sought-after personal spirometer, Spiro PD 2.0, and ... A spirometer is a medical device used to ...
(Date:9/12/2017)... PARIS and NEW YORK , Sept. 12, ... ethical performance ratings for global supply chains, has published the first annual ... the CSR performance of more than 20,400 companies evaluated by EcoVadis, based ... years 2015 and 2016. ... EcoVadis Global CSR Risk & Performance Index ...
Breaking Medicine Technology: