Navigation Links
Genetic Secrets Behind the Dragline Silk

Biologists at the University of California, Riverside have identified the genes, and determined the DNA sequences, for two key proteins in the 'dragline silk' of the black widow spider an advance that may lead to a variety of new materials for industrial, medical and military uses.

The black widow spiders dragline silk is a standout compared to other spider silks because of its superior strength and extensibility, a combination which enables black widow dragline silk to absorb enormous amounts of energy. These properties suggest that synthetically-produced silk might find applications as diverse as lightweight super-strong body armor, components of medical devices and high-tech athletic attire.

The researchers Associate Professor of Biology Cheryl Hayashi, postdoctoral researchers Nadia Ayoub and Jessica Garb, and graduate students Robin Tinghitella and Matthew Collin report their findings in the June 13 online edition of the journal PLoS ONE, published by the Public Library of Science (PLoS).

In the article, they describe their work to identify the genes encoding the two key proteins, named MaSp1 and MaSp2, and determine the genes complete DNA sequences. The UCR Office of Technology Commercialization has filed a patent application on the gene sequences.

There are currently no products on the market based on the dragline silk of spiders. 'Theres nothing quite as good yet as natural dragline silk, but we should get a lot closer now that we have the full genetic recipe,' Hayashi said.

With the ingredients and their genetic blueprint now known, it may be possible to synthetically produce the proteins by inserting the genetic sequences into host organisms such as bacteria, plants or animals, she said. Once the pure proteins are harvested, a manufacturing challenge will be spinning them into silk fibers that have the same remarkable properties as spider spun silk. But several advances have recently be en made in artificial spinning methods.

When spiders manufacture dragline silk, their silk glands produce a 'gooey' slurry of the proteins needed, which are transported to the spinneret through a duct where the proteins interact and align to form the silk strands.

'The production of artificial silk is not quite there yet,' Hayashi said. 'Now, with the full length genes known and as we learn more about theses two proteins, hopefully we will have a better shot at mimicking nature.'

Spider silks have some of the best mechanical properties of any known natural fibers, thus they are being considered in the improvement of a variety of products including surgical microsutures and specialty ropes.

Dragline silk just one type of the seven different silks that an individual spider produces are used by spiders as the structural foundation of their webs and to support their body weight as they move about. The dragline silk of black widows is one of the strongest and toughest spider silks identified thus far.


'"/>




Related medicine news :

1. Genetic Dentistry: Your Dentist may be able to grow you a new set of Teeth.
2. Genetic influence in menopause
3. Genetics and cholesterol levels
4. Genetics helps in attacking cancer
5. Genetic disorder related with sleep patterns
6. Genetic innovation
7. Genetic tests for cancer
8. Genetic indicates memory
9. Genetic mutation to the fountain of youth discovered
10. Genetic differences found between Male and Female brains
11. Alcoholism Influenced By Both Genetics & Family Environment
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/24/2017)... MN (PRWEB) , ... March 24, 2017 , ... ... back to the military at the same time by providing Prehospital Trauma Life ... Guard. PHTLS is the world’s premier prehospital trauma education developed in cooperation with ...
(Date:3/24/2017)... , ... March 24, 2017 , ... According to a ... is invalid because it does not obey the rules Congress has directed the CBO ... jobs, which the GOP reform would restore. Yet, it estimates a reduction in employer-based ...
(Date:3/24/2017)... San Diego, Calif. (PRWEB) , ... March 24, ... ... (ADI) has raised over $100,000 for its innovative EcoQube Frame vertical micro-veggies garden ... demonstrates the instant demand for the product – with nearly 2,000 consumers (and ...
(Date:3/24/2017)... ... March 24, 2017 , ... Viewers who like to educate themselves on ... cultural practices, goods, services, and societal issues tend to appreciate and love the "Informed" ... practice of utilizing running events for causes around the world. , Running ...
(Date:3/24/2017)... , ... March 24, 2017 , ... “End Time GPS”: ... salient events will interrelate. “End Time GPS” is the creation of published author, ... expert while working on military munitions and space-vehicle projects. Now, at age ninety-one, he ...
Breaking Medicine News(10 mins):
(Date:3/24/2017)... Research and Markets has announced the addition of the "Deep ... to their offering. ... The Deep Learning: Drug Discovery and Diagnostics Market, 2017-2035 report examines ... deep learning solutions within the healthcare domain. Primarily driven by the ... solution to generate relevant insights from medical data. ...
(Date:3/24/2017)... YORK , March 24, 2017 ... and Equipment stocks, which are: Neovasc Inc. (NASDAQ: NVCN), Hologic ... Heart Inc. (NASDAQ: SSH ). These companies are ... its prior gains on Thursday, March 23 rd , 2017, ... afternoon, while shares of health care companies in the S&P ...
(Date:3/24/2017)...  Eli Lilly and Company (NYSE: ... million in its U.S. operations in 2017. The ... including research laboratories, manufacturing sites, and general and ... demand for Lilly products, as well as its ... cancer, pain, diabetes and other unmet medical needs.  ...
Breaking Medicine Technology: