Navigation Links
Genetic Risk Factor for Coeliac Disease Identified.

An international research consortium investigating the genetic causes of intestinal inflammatory conditions has identified a new genetic risk factor for coeliac disease.
The study revealed that those suffering from coeliac disease lack a protective DNA sequence in a specific gene region, otherwise found in healthy individuals.

Behind the success of the study are the Human Genome Project and the Hap Map Project, international research efforts to reveal the entire sequence of all the human chromosomes - and the functional units embedded within - and to correlate that information to common sequence variation in the human population.

Dr Panos Deloukas, Senior Investigator in Human Genetics at the Wellcome Trust Sanger Institute, and part of the research consortium, said: These resources coupled with technological advances have enabled us to scan variation across the human genome in large numbers of people for association to disease.

The Sanger Institute made available to the study the genome data on 1500 British individuals used as controls (i.e without coeliac disease). The consortium studied over four thousand individuals with and without coeliac disease, amongst British, Irish and Dutch populations.

What they found is that healthy individuals more often have a protective DNA sequence in the interleukin-2 and interleukin-21 gene region than individuals with coeliac disease. Interleukin-2 and interleukin-21 are cytokine proteins secreted by white blood cells that control inflammation. It is likely that the protective DNA sequence leads to different amounts of these cytokines being produced than in someone with coeliac disease providing defence against intestinal inflammation.

Coeliac disease is found in around 1 in 100 of the British population. It is caused by intolerance to gluten - a protein found in wheat, barley and rye - which results in damage to the gut, preventing normal digestion and absorption
'"/>




Page: 1 2

Related medicine news :

1. Genetic Dentistry: Your Dentist may be able to grow you a new set of Teeth.
2. Genetic influence in menopause
3. Genetics and cholesterol levels
4. Genetics helps in attacking cancer
5. Genetic disorder related with sleep patterns
6. Genetic innovation
7. Genetic tests for cancer
8. Genetic indicates memory
9. Genetic mutation to the fountain of youth discovered
10. Genetic differences found between Male and Female brains
11. Alcoholism Influenced By Both Genetics & Family Environment
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Genetic Risk Factor for Coeliac Disease Identified

(Date:4/18/2015)... 2015 French physician and gastronome Anthelme ... when he uttered, “Tell me what you eat, and ... to cope with stress or sadness has often been ... indicates otherwise. Data collected from their Emotional Eating ... emotional eating, but for different reasons. , Collecting data ...
(Date:4/17/2015)... John Evans, a Gardant affordable assisted living community, ... p.m. to 3 p.m. on April 24. , The ... Pekin, Illinois, serves older adults of all incomes, including ... their independence. , Becky Baker will entertain guests on ... during the luau. , For more information, call 309-477-8800. ...
(Date:4/17/2015)... April 17, 2015 ERGO-Pedic Products, LLC, ... introducing two new products to help a broader range ... pain relief are the second most common visitors to ... product, designed specifically to help relieve sitting pain. Then, ... and thousands of happy customers later, we began getting ...
(Date:4/17/2015)... Canadian, Oklahoma (PRWEB) April 17, 2015 ... and Drug Dependence (NCADD) notes that drinking and driving ... attention. At the same time, the link between ... such as domestic abuse and violence and sexual assault, ... , According to the NCADD, 5.3 million adults in ...
(Date:4/17/2015)... “We have seen healing, a lot of healing, ... said Chaplain Shawn Kafader of Friendship Village. “People have ... anything to contribute have created beautiful pieces of art.” For ... therapy program that was launched to benefit residents of the ... of the Art Institute in Chicago, worked as an intern ...
Breaking Medicine News(10 mins):Health News:It’s Not Just A Girl Thing: Queendom Study Reveals That Men Struggle With Emotional Eating Too 2Health News:It’s Not Just A Girl Thing: Queendom Study Reveals That Men Struggle With Emotional Eating Too 3Health News:It’s Not Just A Girl Thing: Queendom Study Reveals That Men Struggle With Emotional Eating Too 4Health News:It’s Not Just A Girl Thing: Queendom Study Reveals That Men Struggle With Emotional Eating Too 5Health News:It’s Not Just A Girl Thing: Queendom Study Reveals That Men Struggle With Emotional Eating Too 6Health News:John Evans Supportive Living Community Prepares for Party on the Patio 2Health News:Seat Cushion Company Credits Customer Driven Design For Two New Products 2Health News:Narconon Arrowhead Raises Awareness on Alcohol Related Prevention 2Health News:Narconon Arrowhead Raises Awareness on Alcohol Related Prevention 3Health News:Healing At Friendship Village Due To Art Therapy 2
... lock horns over the declaration to be issued after today's ... will fail to effectively contain the epidemic that has claimed ... declaration is to be issued, UN Secretary General Kofi Annan ... earlier declaration in 2001., ,The UNGA's session hoped to ...
... Cross (Indonesia), Mark Snelling, explains about relief operations in earthquake ... ,Over 5,700 were died and more than a thousand were ... that even 24 hours here is an eternity – said ... totally collapsed and 200,000 lost their homes. ,The ...
... says that many were convicted since 1990’s, and in 2004 ... //but the Journal of the Royal Society of Medicine, found ... retribution, Birmingham City Hospital researchers found 85 doctors had been ... vaginal wound and the doctor was drunken, a woman died ...
... on Accident and Emergency Medicine is being held in ... of Indian-American and US doctors.// The objective of this ... institutions the need for specialty faculties for emergency medicine ... the Indian Consulate here Wednesday to launch preparation for ...
... to suspend a ban on smoking in public places, which ... The court ordered that the ban be suspended for 30 ... order such a ban. ,The companies, notably British ... seven days ago before it came into effect and thus ...
... long way to go' before fully understanding how bird ... a concern 'for years to come'//. ,Speaking on ... the Food and Agriculture Organisation (FAO) and the World ... and the illegal trade in infected animals play a ...
Cached Medicine News:Health News:New Delhi to Host Conference on Accident & Emergency Medical Treatment 2Health News:Brid Flu Threat May be a Cause of Concern for Years to Come: Experts 2
(Date:4/17/2015)... Nonin Medical, a global leader in noninvasive ... Officer Steve Bucholz will retire May 1. ... role as Chief Executive Officer. In addition, Mr. Isaacson ... Operations will transition to David Noel , Chief ... been instrumental to Nonin Medical,s growth," Mr. Isaacson said. ...
(Date:4/17/2015)... Apr. 17, 2015 Research and Markets ... "Medical Equipment Rental and Leasing - Global Strategic ... This report analyzes the worldwide markets for Medical Equipment ... separate comprehensive analytics for the US, Japan ... of World. Annual estimates and forecasts are ...
(Date:4/17/2015)... DETROIT , April 17, 2015  In Detroit, ... the infant mortality rate is two and one half times ... births. Nearly 6 of 10 infants that die in ... These are sobering statistics that Covenant Community Care, a faith-based, ... Detroit, is poised to change thanks to a charitable donation ...
Breaking Medicine Technology:Nonin Medical's Philip Isaacson Expands CEO Role; President and COO Steve Bucholz to Retire May 1 2Medical Equipment Rental and Leasing Market 2015-2020 - Global Strategic Business Report - Healthcare Spending Slowdown Bodes Well for Medical Equipment Leasing 2Covenant Community Care to Receive Donated SONIMAGE P3 Handheld Ultrasound from Konica Minolta Medical Imaging 2Covenant Community Care to Receive Donated SONIMAGE P3 Handheld Ultrasound from Konica Minolta Medical Imaging 3Covenant Community Care to Receive Donated SONIMAGE P3 Handheld Ultrasound from Konica Minolta Medical Imaging 4
... Nov. 19 Delcath Systems, Inc. (Nasdaq: DCTH ), ... (PHP(TM)) System, a minimally invasive drug delivery platform for the ... on the Company,s recent progress. , "Since we last communicated ... many significant milestones as we move into the first regulatory ...
... , NEW YORK, Nov. 18 Reportlinker.com ... available in its catalogue. , Medical ... , http://www.reportlinker.com/p0164343/Medical-Ultrasound-Equipment---A-Global-Market-Perspective.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=prnewswire , ... ultrasound has engulfed a major share of the ...
Cached Medicine Technology:Delcath Systems Reports Substantial Progress 2Delcath Systems Reports Substantial Progress 3Delcath Systems Reports Substantial Progress 4Reportlinker Adds Medical Ultrasound Equipment - A Global Market Perspective 2Reportlinker Adds Medical Ultrasound Equipment - A Global Market Perspective 3Reportlinker Adds Medical Ultrasound Equipment - A Global Market Perspective 4Reportlinker Adds Medical Ultrasound Equipment - A Global Market Perspective 5Reportlinker Adds Medical Ultrasound Equipment - A Global Market Perspective 6Reportlinker Adds Medical Ultrasound Equipment - A Global Market Perspective 7Reportlinker Adds Medical Ultrasound Equipment - A Global Market Perspective 8
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: