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Genetic Map Reveals How Drugs Fight Diseases: Study

disease, and made entirely new ones too."

One of the surprising results emerging from the connectivity map involves gedunin, a plant derivative that, despite a long history of medicinal use, is not well understood molecularly.

Another key finding suggests a new way to overcome drug resistance in cancer, according to the researchers.

Using the connectivity map, another team led by Scott Armstrong, an assistant professor at Harvard Medical School, identified the FDA-approved immunosuppressant drug sirolimus, as a therapeutic candidate for overcoming drug resistance in a form of human leukemia.

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