Navigation Links
Genetic Expressions Can Influence The Process Of Aging

Researchers of Cold Spring Harbor laboratory have discovered that the loss of a gene called p63 accelerates the process of aging. Similar versions of the gene are present in many organisms, including humans // . Drawing parallels from mice, the researchers had concluded that the p63 gene is likely to play a fundamental biological role in aging-related processes.

To study how the p63 gene works, the researchers had devised a system for eliminating it from adult mouse tissues. The result was seen in the p63 deficient mice, which were aging prematurely.

Mice that are born without the p63 gene do not survive. Therefore, Mills had previously conducted extensive studies of mice that are born with only one copy of the gene. Still, these animals die at a young age. So to study p63 function in adults, Mills and her colleagues devised a sophisticated molecular genetic technique that enabled them to eliminate both copies of the gene from particular tissues including skin and other multi-layered epithelial tissues after the animals reached maturity.

The effects of premature aging observed in these p63 deficient mice (image available on request) were hair loss, reduced fitness and body weight, progressive curvature of the spine, and a shortened lifespan.

The researchers had opined that aging and cancer are two sides of the same coin. In one case, cells stop dividing and in the other, they can't stop dividing. They said that it might be possible that having the right amount of the p63 protein in the right cells at the right time creates a balance that enables organisms to live relatively cancer-free for a reasonably long time. This is the first time the p63 gene has been implicated in aging.

The study is published in the September issue of the journal Genes & Development.

Source: Newswise
'"/>




Page: 1

Related medicine news :

1. Genetic Dentistry: Your Dentist may be able to grow you a new set of Teeth.
2. Genetic influence in menopause
3. Genetics and cholesterol levels
4. Genetics helps in attacking cancer
5. Genetic disorder related with sleep patterns
6. Genetic innovation
7. Genetic tests for cancer
8. Genetic indicates memory
9. Genetic mutation to the fountain of youth discovered
10. Genetic differences found between Male and Female brains
11. Alcoholism Influenced By Both Genetics & Family Environment
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/21/2017)... (PRWEB) , ... July 21, 2017 , ... ... management assistance and financial planning services to families and business owners in northern ... event that promises to provide support to area adults with developmental challenges. , ...
(Date:7/21/2017)... ... July 21, 2017 , ... Adolfson & ... and improve the Ramsey County Medical Examiners Facility located in Saint Paul, Minn. ... million project is scheduled to start in late 2017/early 2018. , Staffed ...
(Date:7/21/2017)... ... July 21, 2017 , ... ... Theater of Witness , was awarded a $300,000 grant from The Pew ... fosters empathy, comfort with ambiguity and the recognition of one’s own limits among ...
(Date:7/21/2017)... , ... July 21, 2017 , ... Bernard R. Bach, ... President of the American Orthopaedic Society of Sports Medicine (AOSSM) , received the ... the AOSSM Annual Meeting in Toronto, Canada. This prestigious award is given annually to ...
(Date:7/21/2017)... , ... July 21, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The House ... use of violence and aggression to solve problems and pleads with world leaders to be ... armed forces do not bring peace. He says there is a peaceful and positive way ...
Breaking Medicine News(10 mins):
(Date:7/21/2017)... SPRING, Md. and RESEARCH TRIANGLE ... United Therapeutics Corporation (NASDAQ: UTHR ) announced ... financial results before the market opens on Thursday, July ... Therapeutics will host a teleconference on Thursday, July 27, ... accessible by dialing 1-877-351-5881, with international callers dialing 1-970-315-0533.  ...
(Date:7/19/2017)... , July 19, 2017  Mako Medical Laboratories partnered ... the Military Family Assistance Fund (MFA) to bring 140 ... to visit with their families one last time before ... coordinate the travel and logistics needed for these soldiers. ... soldiers and their families. We just wish we could ...
(Date:7/14/2017)... , July 13, 2017 It should come ... States is in the midst of a crippling ... , since 1999, the number of overdose deaths from opiate-based ... in over half a million dead from 2001 to 2015". ... oxycodone, and hydrocodone has similarly quadrupled, drawing a compelling link ...
Breaking Medicine Technology: