Navigation Links
Genes That Were Responsible For The Cause Of Blindness Identified

Scientists have identified those two genes that were responsible for the cause of blindness that affects millions of older people // throughout the world and they added that the new development could pave way for new treatments.

Nearly three-quarters of people in the world suffer from age-related macular degeneration (AMD) a most common cause of blindness. AMD is marked by a progressive loss of central vision due to degeneration of the macula - a region of the retina responsible for fine, central vision.

Researchers at New York's Columbia University studied 1,300 people and found that this common cause of blindness was linked to just two genes - Factor H and Factor B. While Factor H is an inhibitor of the immune response to infection, Factor B is an activator, the online edition of BBC News reported.

"I am not aware of any other complex disorder where nearly 75 percent of genetic causality has been identified," lead researcher Rando Allikmets said.

Factor H controls the production of a protein that helps shut down the body's immune response to infection once it has been successfully fought off.

People with these inherited variants of Factor H are less able to control inflammation caused by infectious triggers, which may spark AMD in later life, they said.

The researchers found 74 percent of the people with AMD had either the Factor H or Factor B risk factor or both - but no protective variants of either gene.

"These findings are significant because they absolutely confirm the roles of these two genes and, consequently, the central role of a specific immune response pathway, in the development of AMD," Allikmets said.

"In just a few short years, we've gone from knowing very little about what causes AMD to knowing quite a lot. We now have clear targets for early therapeutic intervention," Allikmets said.

The researchers are now searching for the specific t riggers that set off the immune response, and subsequent inflammation.

--Edited IANS
'"/>




Related medicine news :

1. New Way to "See" Genes, Evaluate Effectiveness of Gene Therapies Discovered
2. Genes for lung disease
3. Genesis of SUPAC
4. Genes for Vision discovered
5. Genes Found To Help Leukemia Treatment
6. Cardiac Valve Disease Linked To Genes
7. Genes Linked To Cigarette Addiction
8. Genes from saliva may predict oral and breast cancer
9. Genes More Important Than Exercise for Bad Cholesterol
10. Genes responsible for social behavior of us
11. Genes to Extend Longevity Discovered
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/27/2016)... (PRWEB) , ... May 27, 2016 , ... ... this installment is bolstered by inspiring human interest stories, courtesy of leaders in ... trends and tech within the industry, from leading advocates and associations—namely Jones & ...
(Date:5/26/2016)... ... May 26, 2016 , ... There are many ways to ... Sausage Council (NHDSC) suggests that Americans prefer their dogs straight off the grill. Of ... grilling is their favorite way to cook a hot dog, far outpacing other cooking ...
(Date:5/26/2016)... , ... May 26, 2016 , ... Connor Sports, ... basketball as a partner for the Tamika Catchings Legacy Tour that will ... industry leader in hardwood basketball surfaces in all forms and levels of the game, ...
(Date:5/26/2016)... ... ... MadgeTech will be showcasing its line of data logging products , ... MadgeTech headquarters. With products sold in more than 100 countries around the world, MadgeTech ... , In 2012, NASA strategically set up 17 RHTemp101A MadgeTech data loggers around ...
(Date:5/26/2016)... (PRWEB) , ... May 26, 2016 , ... Memorial Day ... why Amica Insurance is sharing tips to make sure your family and ... from the National Safety Council, there may be 439 deaths and an additional 50,500 ...
Breaking Medicine News(10 mins):
(Date:5/27/2016)... the necessity of health literacy within the technology advancement of diagnostic imaging. According to a ... majority of oncology patients undergo imaging screenings without understanding the nuanced risks associated with ... ... ... Diagnostic Imaging Ampronix ...
(Date:5/27/2016)... Israel , May 27, 2016 ... of the Dario™ Diabetes Management Tool, today announced that the ... at the Marcum MicroCap Conference being held June 1-2 in ... Micro Invitational, being held June 7-9 in Los ... Ben-David will discuss recent corporate and operational milestones, including the ...
(Date:5/27/2016)... According to the 2016 report, ... ambulatory blood pressure monitoring system market growth. With aging, ... to respond to different pressure rates, leading to hypertension ... various cardiovascular disorders such as heart failure, stroke, coronary ... growing in prevalence each year. WHO estimates that 17 ...
Breaking Medicine Technology: