Navigation Links
Genes Responsible for a Blinding Condition Identified

A US study says that two genes could determine the vulnerability of the elderly to an advanced form of age-related macular degeneration// (AMD), researchers report.

Age-related macular degeneration (AMD) is a disease associated with aging that gradually destroys sharp, central vision. Central vision is needed for seeing objects clearly and for common daily tasks such as reading and driving.

AMD affects the macula, the part of the eye that allows you to see fine detail. AMD causes no pain, though.

In some cases, AMD advances so slowly that people notice little change in their vision. In others, the disease progresses faster and may lead to a loss of vision in both eyes. AMD is a leading cause of vision loss in Americans 60 years of age and older.

Also people who smoked or were overweight faced an even greater risk of the potentially blinding eye condition, the new study found.

'The two genetic variants are related and predict to a certain extent which individuals who have earlier-intermediate forms of macular degeneration progress to the advanced form and visual loss,' explained the study's lead author, Dr. Johanna M. Seddon, director of the Ophthalmic, Epidemiology and Genetics Service in the department of ophthalmology at Tufts-New England Medical Center and New England Eye Center.

'Genetic variants are part of the way we can differentiate who gets worse, coupled with environmental factors like a high body mass index and smoking,' said Seddon, whose team published its results in the April 25 issue of the Journal of the American Medical Association.

The findings have implications for the prevention of AMD, one expert said.

'They've actually identified specific genes and specific abnormalities in specific genes that prove that macular degeneration has a strong genetic component,' said Dr. Robert Cykiert, clinical associate professor of ophthalmology at New York University School of Medic ine in New York City. 'What this says is if you have someone in your immediate family such as parents or siblings with AMD, then you need to see an ophthalmologist and be carefully followed, because there are things that can be done to prevent progression.'

Down the line, there may even be a blood test to detect these genes, further brightening the picture for prevention and early treatment, Cykiert said.

But it's too early to recommend widespread screening, the authors stated.

'Some individuals who progress do not have these genetic variants or have never smoked,' Seddon said. 'We need to refine this predictive measure, add more genetic variants and maybe even more environmental factors.'
GPL/B
'"/>




Related medicine news :

1. New Way to "See" Genes, Evaluate Effectiveness of Gene Therapies Discovered
2. Genes for lung disease
3. Genesis of SUPAC
4. Genes for Vision discovered
5. Genes Found To Help Leukemia Treatment
6. Cardiac Valve Disease Linked To Genes
7. Genes Linked To Cigarette Addiction
8. Genes from saliva may predict oral and breast cancer
9. Genes More Important Than Exercise for Bad Cholesterol
10. Genes responsible for social behavior of us
11. Genes to Extend Longevity Discovered
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/24/2017)... ... , ... Digital Scientists, a software innovation lab specializing in web design and ... South Carolina location. The lab has set up shop at the renowned NEXT ... South Carolina clients for years from our office here in Atlanta,” explains Digital Scientists’ ...
(Date:3/24/2017)... ... March 24, 2017 , ... The iaedp Foundation, the premier provider of educational ... those suffering from the full spectrum of disordered eating, announced today that the 2017 ... nearly all 50 states and several countries converged on the Green Valley Resort in ...
(Date:3/24/2017)... ... March 24, 2017 , ... As the standards bearer of ... platform that positions them as the go-to thought leader in all matters concerning ... as an always-on, always-fresh news, views and advocacy engine, called ONS Voice. , ...
(Date:3/24/2017)... (PRWEB) , ... March 24, 2017 , ... Viewers who ... variety of critical historical facts, cultural practices, goods, services, and societal issues tend to ... will look into the popular practice of utilizing running events for causes around the ...
(Date:3/24/2017)... ... , ... “Finding Christ Through Social Media: Year One #A365DayJourney ... writer’s path toward true communion with God. “Finding Christ Through Social Media: Year ... of published author Lea Michelle Johnson, a follower of Christ, wife and mother ...
Breaking Medicine News(10 mins):
(Date:3/23/2017)... , Mar 23, 2017 Research and Markets ... & Trends - Industry Forecast to 2025" report to their ... The ... around 6.9% over the next decade to reach approximately $3.5 billion ... and forecasts for all the given segments on global as well ...
(Date:3/23/2017)... , March 23, 2017  Transportation Insight, a ... an end-to-end supply chain management firm with expertise serving ... Product Solutions Rick Zaffarano was named a ... the Supply Chain by the only publication exclusively dedicated ... food supply chain. "Rick has brought to ...
(Date:3/23/2017)... SILVER SPRING, Md. , March 23, 2017 /PRNewswire-USNewswire/ ... approval to Bavencio (avelumab) for the treatment of adults ... Merkel cell carcinoma (MCC), including those who have not ... for metastatic MCC, a rare, aggressive form of skin ... the most common cancers, patients with a rare form ...
Breaking Medicine Technology: