Navigation Links
Genes Responsible for a Blinding Condition Identified

A US study says that two genes could determine the vulnerability of the elderly to an advanced form of age-related macular degeneration// (AMD), researchers report.

Age-related macular degeneration (AMD) is a disease associated with aging that gradually destroys sharp, central vision. Central vision is needed for seeing objects clearly and for common daily tasks such as reading and driving.

AMD affects the macula, the part of the eye that allows you to see fine detail. AMD causes no pain, though.

In some cases, AMD advances so slowly that people notice little change in their vision. In others, the disease progresses faster and may lead to a loss of vision in both eyes. AMD is a leading cause of vision loss in Americans 60 years of age and older.

Also people who smoked or were overweight faced an even greater risk of the potentially blinding eye condition, the new study found.

'The two genetic variants are related and predict to a certain extent which individuals who have earlier-intermediate forms of macular degeneration progress to the advanced form and visual loss,' explained the study's lead author, Dr. Johanna M. Seddon, director of the Ophthalmic, Epidemiology and Genetics Service in the department of ophthalmology at Tufts-New England Medical Center and New England Eye Center.

'Genetic variants are part of the way we can differentiate who gets worse, coupled with environmental factors like a high body mass index and smoking,' said Seddon, whose team published its results in the April 25 issue of the Journal of the American Medical Association.

The findings have implications for the prevention of AMD, one expert said.

'They've actually identified specific genes and specific abnormalities in specific genes that prove that macular degeneration has a strong genetic component,' said Dr. Robert Cykiert, clinical associate professor of ophthalmology at New York University School of Medic ine in New York City. 'What this says is if you have someone in your immediate family such as parents or siblings with AMD, then you need to see an ophthalmologist and be carefully followed, because there are things that can be done to prevent progression.'

Down the line, there may even be a blood test to detect these genes, further brightening the picture for prevention and early treatment, Cykiert said.

But it's too early to recommend widespread screening, the authors stated.

'Some individuals who progress do not have these genetic variants or have never smoked,' Seddon said. 'We need to refine this predictive measure, add more genetic variants and maybe even more environmental factors.'
GPL/B
'"/>




Related medicine news :

1. New Way to "See" Genes, Evaluate Effectiveness of Gene Therapies Discovered
2. Genes for lung disease
3. Genesis of SUPAC
4. Genes for Vision discovered
5. Genes Found To Help Leukemia Treatment
6. Cardiac Valve Disease Linked To Genes
7. Genes Linked To Cigarette Addiction
8. Genes from saliva may predict oral and breast cancer
9. Genes More Important Than Exercise for Bad Cholesterol
10. Genes responsible for social behavior of us
11. Genes to Extend Longevity Discovered
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/21/2017)... ... April 21, 2017 , ... Dudnyk has announced the launch of ... conviction that the full potential of specialty and orphan brands can only be achieved ... , “The Unifying Effect is at the heart of a true partnership between ...
(Date:4/21/2017)... (PRWEB) , ... April 21, 2017 , ... The Hong ... the first 3D printing facility among higher education institutions in Hong Kong to support ... in terms of the range and quantity of facilities in Hong Kong. , ...
(Date:4/21/2017)... ... April 21, 2017 , ... Airway Management, the medical ... the highly regarded and well renowned Asian distributor, Discovery Sleep. The ... Nasal Pillow Mask, and will stabilize and strengthen Airway’s presence with a dedicated, ...
(Date:4/21/2017)... CA (PRWEB) , ... April 21, 2017 , ... Providing ... not understand the estate planning process, or where to even begin. “Now more than ... if you are to properly protect yourself and your family,” said attorney Lisa Edgar ...
(Date:4/21/2017)... ... 21, 2017 , ... Each year, everyone is urged to give back to ... and look forward to a better future. However, supporting the environment should be an ... quality can be two to five times more polluted than outdoor air, reports the ...
Breaking Medicine News(10 mins):
(Date:4/19/2017)... /PRNewswire/ - CRH Medical Corporation (TSX: CRH) (NYSE MKT: CRHM) (the "Company"), announces ... Investor Conference 2017 at the Sheraton Hotel in Toronto, ... Officer of the Company is scheduled to present on Tuesday, May ... and the Chairman of the Board, Tony Holler will ... For ...
(Date:4/19/2017)... NEW YORK , April 19, 2017 The ... anticipated to showcase a healthy CAGR during the forecast period ... product type in the global digital mobile X-Ray devices market, ... 2,000 Mn in 2017, expanding at a CAGR of 7% ... create absolute $ opportunity of more than US$ 100 Mn ...
(Date:4/19/2017)... Global Surgical Drainage Device Market: Overview ... remove excess liquid and air. The fluid to be ... lymph. Surgical drains are used in a wide variety ... cardiovascular surgery, neurosurgery, plastic surgery etc. Common use of ... of fluid e.g. blood or pus. Surgical drains are ...
Breaking Medicine Technology: