Navigation Links
Genes Play Major Role in Determining Individual's Sour Taste Perception

Scientists at the Monell Chemical Senses Center have revealed that genes play a large role in determining individual differences in sour taste perception.

The findings may help researchers identify the still-elusive taste receptor that detects sourness in foods and beverages, just as recent gene studies helped uncover receptors for sweet and bitter taste.

Scientists have long known that sour taste is stimulated by acids in foods and beverages. In fact, the word acid is derived from the Latin 'acidus,' meaning sour. However, we still do not completely understand how the taste system is able to detect and translate acidic molecules on the tongue into a neural signal that the brain perceives as 'sour.'

"Demonstrating a genetic component to individual differences in sour taste is the first step in pinpointing the genes that determine sensitivity. The products of those genes, in turn, are likely to be involved in sour taste perception," said study lead author Paul M. Wise, PhD, a Monell sensory psychologist.

In the study, published online in advance of print in the journal Chemical Senses, researchers tested 74 pairs of monozygotic (MZ, identical) twins and 35 pairs of dizygotic (DZ, fraternal) twins to determine the lowest concentration needed for each twin to correctly identify a citric acid solution as 'sour.'

Because MZ twins have nearly identical genes while DZ twins share only about 50 pct of their genes, more similar responses in MZ than DZ pairs suggests that genes help determine sensitivity to the taste in question.

Responses were compared within the twin pairs, and then entered into a computer model to determine the relative contributions of genetic and environmental influences on sour taste sensitivity.

The models estimated that genes played a more important role than environment in determining individual differences in sour taste sensitivity, accounting for 53 percent of the variation.

The finding that genes influence sour taste perception suggest that genetic analyses could potentially help identify sour receptors. Future studies will evaluate possible receptors by determining whether individual differences in genes for these structures - such as the recently-discovered PKD ion channel - are correlated with individual differences in sensitivity to sourness.

For any given candidate receptor, a strong association of genetic with perceptual variation would support the likelihood that the receptor detects sour taste.

The findings, in conjunction with previous work on sweet, bitter, and umami (savoury) taste, suggest that people differ in how they perceive the taste of foods, and that these differences are determined in part by their taste genes. So someone who inherited a high sensitivity to sour taste may find foods containing lemons or vinegar off-putting, whereas the same foods may be better accepted by a person whose genes make them less sensitive.

"These taste perceptions presumably evolved because they have a significant impact on food choice and therefore nutrition. If we can understand how and why people differ in their taste perception, we might eventually be able to manipulate the taste of individual diets to help encourage healthy eating," Wise said.


'"/>




Related medicine news :

1. New Way to "See" Genes, Evaluate Effectiveness of Gene Therapies Discovered
2. Genes for lung disease
3. Genesis of SUPAC
4. Genes for Vision discovered
5. Genes Found To Help Leukemia Treatment
6. Cardiac Valve Disease Linked To Genes
7. Genes Linked To Cigarette Addiction
8. Genes from saliva may predict oral and breast cancer
9. Genes More Important Than Exercise for Bad Cholesterol
10. Genes responsible for social behavior of us
11. Genes to Extend Longevity Discovered
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/12/2017)... ... 2017 , ... The company has developed a suite of ... authorities worldwide. From Children’s to Adults 50+, every formula has been developed by ... , These products are also: Gluten Free, Non-GMO, Vegan, Soy Free, Non-Dairy*, Preservative ...
(Date:10/12/2017)... ... October 12, 2017 , ... Asante, a nationally ... care, have expanded their existing home health joint venture through an agreement, effective ... operating a joint venture home health company with Asante, delivering clinically integrated care, ...
(Date:10/12/2017)... , ... October 12, 2017 , ... HMP , ... recipient of a 2017 Folio Magazine Eddie Digital Award for ‘Best B-to-B Healthcare Website.’ ... on October 11, 2017. , The annual award competition recognizes editorial and design excellence ...
(Date:10/12/2017)... ... October 12, 2017 , ... Women-owned and Grand Rapids-based workplace ... Brightest in Wellness® by Best and Brightest. OnSite Wellness will be honored at ... from 7:30 a.m. to 2 p.m. at the Henry Autograph Collection Hotel, located ...
(Date:10/12/2017)... ... October 12, 2017 , ... Vohra Chief Medical ... to physician colleagues, skilled nursing facility medical directors and other clinicians at various ... Wound Care." , "At many of these conferences we get to educate other ...
Breaking Medicine News(10 mins):
(Date:9/25/2017)... , Sept. 25, 2017  EpiVax, Inc., ... vaccine design, and immune-engineering today announced the launch ... the development of personalized therapeutic cancer vaccines. EpiVax ... provided exclusive access to enabling technologies to the ... MBA will lead EpiVax Oncology as Chief Executive ...
(Date:9/19/2017)...   ZirMed Inc ., a recognized leader in cloud-based ... has been ranked #1 by its users for the seventh ... User Survey. ZirMed was recognized as the top-ranked end-to-end revenue ... centers over 200 beds and holds one of the longest ... history. ...
(Date:9/12/2017)... reviews on the independent review site Consumer Affairs have ... hearing aids, ranking it higher than Miracle Ear ™, Beltone™, ... ... Aids ... that provides high performance, state-of-the-art, German-engineered hearing aids directly to consumers ...
Breaking Medicine Technology: